| Full name: ribosomal protein L18a | Alias Symbol: L18A | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 6142 | HGNC ID: HGNC:10311 | Ensembl Gene: ENSG00000105640 | OMIM ID: 604178 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPL18A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | RPL18A | 6142 | 33453 | -0.3154 | 0.0000 | |
| GSE53624 | RPL18A | 6142 | 33453 | -0.1723 | 0.0054 | |
| GSE97050 | RPL18A | 6142 | A_32_P193288 | -0.2994 | 0.4376 | |
| SRP007169 | RPL18A | 6142 | RNAseq | -1.1994 | 0.0023 | |
| SRP008496 | RPL18A | 6142 | RNAseq | -1.1512 | 0.0000 | |
| SRP064894 | RPL18A | 6142 | RNAseq | -0.0417 | 0.9148 | |
| SRP133303 | RPL18A | 6142 | RNAseq | -0.5425 | 0.0002 | |
| SRP159526 | RPL18A | 6142 | RNAseq | -0.7813 | 0.0003 | |
| SRP193095 | RPL18A | 6142 | RNAseq | -0.8286 | 0.0000 | |
| SRP219564 | RPL18A | 6142 | RNAseq | 0.1953 | 0.6878 | |
| TCGA | RPL18A | 6142 | RNAseq | 0.0997 | 0.2880 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RPL18A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL18A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL18A | 6142 | 4 | 4 | 22 | |
| GSE20123 | RPL18A | 6142 | 3 | 2 | 25 | |
| GSE43470 | RPL18A | 6142 | 2 | 6 | 35 | |
| GSE46452 | RPL18A | 6142 | 47 | 1 | 11 | |
| GSE47630 | RPL18A | 6142 | 4 | 8 | 28 | |
| GSE54993 | RPL18A | 6142 | 15 | 4 | 51 | |
| GSE54994 | RPL18A | 6142 | 6 | 14 | 33 | |
| GSE60625 | RPL18A | 6142 | 9 | 0 | 2 | |
| GSE74703 | RPL18A | 6142 | 2 | 4 | 30 | |
| GSE74704 | RPL18A | 6142 | 0 | 2 | 18 | |
| TCGA | RPL18A | 6142 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of RPL18A:
Generating mutation plots.
Highly correlated genes for RPL18A:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL18A | RPL29 | 0.779317 | 3 | 0 | 3 |
| RPL18A | RPS9 | 0.749917 | 3 | 0 | 3 |
| RPL18A | RPLP0 | 0.740232 | 3 | 0 | 3 |
| RPL18A | RPS5 | 0.71107 | 3 | 0 | 3 |
| RPL18A | RPS16 | 0.70851 | 3 | 0 | 3 |
| RPL18A | RPS19 | 0.691884 | 3 | 0 | 3 |
| RPL18A | RPL23A | 0.683103 | 3 | 0 | 3 |
| RPL18A | RPS11 | 0.680103 | 3 | 0 | 3 |
| RPL18A | RPL36 | 0.67447 | 3 | 0 | 3 |
| RPL18A | RPS14 | 0.666613 | 4 | 0 | 3 |
| RPL18A | UBA52 | 0.665271 | 4 | 0 | 3 |
| RPL18A | RPL18 | 0.640898 | 4 | 0 | 3 |
| RPL18A | RPL37A | 0.635127 | 4 | 0 | 3 |
| RPL18A | RPS8 | 0.624976 | 4 | 0 | 3 |
| RPL18A | RPL3 | 0.621847 | 3 | 0 | 3 |
| RPL18A | RPL10A | 0.617465 | 4 | 0 | 4 |
| RPL18A | RPS18 | 0.612278 | 4 | 0 | 3 |
| RPL18A | EEF2 | 0.608489 | 4 | 0 | 3 |
| RPL18A | RPS13 | 0.601964 | 4 | 0 | 3 |
| RPL18A | RPL15 | 0.600166 | 4 | 0 | 3 |
For details and further investigation, click here
