N4BP2L1

 

Full name: NEDD4 binding protein 2 like 1 Alias Symbol: CG018
Type: protein-coding gene Cytoband: 13q13.1
Entrez ID: 90634 HGNC ID: HGNC:25037 Ensembl Gene: ENSG00000139597 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of N4BP2L1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 N4BP2L1 90634 213375_s_at -0.7646 0.3117
GSE20347 N4BP2L1 90634 213375_s_at -0.8268 0.0080
GSE23400 N4BP2L1 90634 214906_x_at -0.1200 0.0145
GSE26886 N4BP2L1 90634 213375_s_at -0.3089 0.6481
GSE29001 N4BP2L1 90634 213375_s_at -0.7248 0.0736
GSE38129 N4BP2L1 90634 213375_s_at -0.8468 0.0015
GSE45670 N4BP2L1 90634 213375_s_at -1.6739 0.0002
GSE53622 N4BP2L1 90634 111080 -0.5702 0.0000
GSE53624 N4BP2L1 90634 111080 -0.9852 0.0000
GSE63941 N4BP2L1 90634 214906_x_at 0.2755 0.5409
GSE77861 N4BP2L1 90634 214906_x_at -0.1415 0.2370
GSE97050 N4BP2L1 90634 A_33_P3245415 -0.2242 0.3565
SRP007169 N4BP2L1 90634 RNAseq -0.8457 0.1357
SRP008496 N4BP2L1 90634 RNAseq -0.8524 0.0153
SRP064894 N4BP2L1 90634 RNAseq -0.3339 0.1401
SRP133303 N4BP2L1 90634 RNAseq -0.7913 0.0003
SRP159526 N4BP2L1 90634 RNAseq -0.3780 0.4774
SRP193095 N4BP2L1 90634 RNAseq -0.6359 0.0000
SRP219564 N4BP2L1 90634 RNAseq -0.2449 0.2963
TCGA N4BP2L1 90634 RNAseq -0.1910 0.2366

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by N4BP2L1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of N4BP2L1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 N4BP2L1 90634 1 15 14
GSE20123 N4BP2L1 90634 1 14 15
GSE43470 N4BP2L1 90634 2 13 28
GSE46452 N4BP2L1 90634 0 33 26
GSE47630 N4BP2L1 90634 2 27 11
GSE54993 N4BP2L1 90634 12 2 56
GSE54994 N4BP2L1 90634 2 15 36
GSE60625 N4BP2L1 90634 0 3 8
GSE74703 N4BP2L1 90634 2 10 24
GSE74704 N4BP2L1 90634 0 12 8
TCGA N4BP2L1 90634 8 37 51

Total number of gains: 30; Total number of losses: 181; Total Number of normals: 277.  


 

Somatic mutations of N4BP2L1:

 

Generating mutation plots.

 

Highly correlated genes for N4BP2L1:

 

Showing top 20/881 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
N4BP2L1AFF30.755881303
N4BP2L1UBXN10.741663303
N4BP2L1THUMPD10.73933404
N4BP2L1ZYG11B0.734846303
N4BP2L1EIF1AY0.733877303
N4BP2L1ATF60.731244404
N4BP2L1AZIN10.71414303
N4BP2L1KCNT20.712998505
N4BP2L1ZMAT10.712955706
N4BP2L1RAB9B0.709527505
N4BP2L1ZNF2250.709084303
N4BP2L1SMTNL20.707197505
N4BP2L1PPM1K0.70643504
N4BP2L1IFITM100.704604303
N4BP2L1RNF1250.703694605
N4BP2L1KIAA11430.701411303
N4BP2L1NR3C20.700885808
N4BP2L1RECK0.698057403
N4BP2L1PCGF50.69749606
N4BP2L1CNOT6L0.695741606

For details and further investigation, click here