SCML2

 

Full name: Scm polycomb group protein like 2 Alias Symbol: 
Type: protein-coding gene Cytoband: Xp22.13
Entrez ID: 10389 HGNC ID: HGNC:10581 Ensembl Gene: ENSG00000102098 OMIM ID: 300208
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of SCML2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SCML2 10389 206147_x_at -0.0749 0.8829
GSE20347 SCML2 10389 206147_x_at 0.0763 0.4682
GSE23400 SCML2 10389 206147_x_at 0.0175 0.6010
GSE26886 SCML2 10389 206147_x_at 0.2408 0.2153
GSE29001 SCML2 10389 206147_x_at -0.0248 0.9545
GSE38129 SCML2 10389 206147_x_at -0.0081 0.9348
GSE45670 SCML2 10389 206147_x_at -0.0692 0.7581
GSE53622 SCML2 10389 87222 -0.1777 0.4489
GSE53624 SCML2 10389 87222 0.3661 0.0475
GSE63941 SCML2 10389 206147_x_at 0.5447 0.1425
GSE77861 SCML2 10389 206147_x_at -0.0225 0.8641
SRP007169 SCML2 10389 RNAseq 0.4922 0.5115
SRP008496 SCML2 10389 RNAseq 0.3769 0.4086
SRP064894 SCML2 10389 RNAseq -0.2618 0.2927
SRP133303 SCML2 10389 RNAseq 0.4897 0.1568
SRP159526 SCML2 10389 RNAseq 1.0826 0.0428
SRP193095 SCML2 10389 RNAseq 0.2920 0.2139
TCGA SCML2 10389 RNAseq 0.4744 0.0865

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by SCML2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SCML2:

 

No record found for this gene.


 

Somatic mutations of SCML2:

 

Generating mutation plots.

 

Highly correlated genes for SCML2:

 

Showing top 20/23 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SCML2PRKAG2-AS10.68196303
SCML2ZNF5990.628186303
SCML2BCL20.611871303
SCML2NEK40.596372504
SCML2OR5P30.593187403
SCML2PDE9A0.570185303
SCML2CACNA2D40.568579403
SCML2PRKAR2B0.561647403
SCML2SCML10.5581711005
SCML2FOCAD0.556721303
SCML2NNT0.549952303
SCML2BEX20.549529403
SCML2F80.542376503
SCML2ABHD100.542298403
SCML2ZNF2390.535607403
SCML2SNAPC30.529677303
SCML2ZNF4190.527158403
SCML2MCF2L-AS10.525975503
SCML2PHKA20.523608603
SCML2CEP440.512641403

For details and further investigation, click here