| Full name: focadhesin | Alias Symbol: FLJ20375 | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 54914 | HGNC ID: HGNC:23377 | Ensembl Gene: ENSG00000188352 | OMIM ID: 614606 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FOCAD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOCAD | 54914 | 218503_at | -0.3721 | 0.7396 | |
| GSE20347 | FOCAD | 54914 | 218503_at | -0.4027 | 0.0107 | |
| GSE23400 | FOCAD | 54914 | 218503_at | -0.0458 | 0.6103 | |
| GSE26886 | FOCAD | 54914 | 218503_at | -0.1326 | 0.5446 | |
| GSE29001 | FOCAD | 54914 | 218503_at | -0.4449 | 0.2011 | |
| GSE38129 | FOCAD | 54914 | 218503_at | -0.2869 | 0.0145 | |
| GSE45670 | FOCAD | 54914 | 218503_at | -0.0417 | 0.8441 | |
| GSE53622 | FOCAD | 54914 | 116676 | -0.3905 | 0.0000 | |
| GSE53624 | FOCAD | 54914 | 116676 | -0.2484 | 0.0105 | |
| GSE63941 | FOCAD | 54914 | 218503_at | -0.5454 | 0.5813 | |
| GSE77861 | FOCAD | 54914 | 218503_at | -0.6561 | 0.1333 | |
| SRP007169 | FOCAD | 54914 | RNAseq | -0.1338 | 0.7685 | |
| SRP008496 | FOCAD | 54914 | RNAseq | -0.0884 | 0.7259 | |
| SRP064894 | FOCAD | 54914 | RNAseq | -0.0012 | 0.9930 | |
| SRP133303 | FOCAD | 54914 | RNAseq | -0.0810 | 0.6148 | |
| SRP159526 | FOCAD | 54914 | RNAseq | -0.2276 | 0.4299 | |
| SRP193095 | FOCAD | 54914 | RNAseq | -0.2383 | 0.2020 | |
| SRP219564 | FOCAD | 54914 | RNAseq | -0.2538 | 0.4530 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FOCAD expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of FOCAD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOCAD | 54914 | 2 | 16 | 12 | |
| GSE20123 | FOCAD | 54914 | 2 | 16 | 12 | |
| GSE43470 | FOCAD | 54914 | 4 | 13 | 26 | |
| GSE46452 | FOCAD | 54914 | 2 | 23 | 34 | |
| GSE47630 | FOCAD | 54914 | 3 | 27 | 10 | |
| GSE54993 | FOCAD | 54914 | 7 | 2 | 61 | |
| GSE54994 | FOCAD | 54914 | 8 | 16 | 29 | |
| GSE60625 | FOCAD | 54914 | 3 | 0 | 8 | |
| GSE74703 | FOCAD | 54914 | 4 | 10 | 22 | |
| GSE74704 | FOCAD | 54914 | 0 | 13 | 7 | |
| TCGA | FOCAD | 54914 | 10 | 54 | 32 |
Total number of gains: 45; Total number of losses: 190; Total Number of normals: 253.
Somatic mutations of FOCAD:
Generating mutation plots.
Highly correlated genes for FOCAD:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOCAD | PARP16 | 0.656355 | 4 | 0 | 4 |
| FOCAD | DCAF10 | 0.649379 | 5 | 0 | 4 |
| FOCAD | BRCC3 | 0.643909 | 3 | 0 | 3 |
| FOCAD | HDHD2 | 0.641247 | 3 | 0 | 3 |
| FOCAD | ZNF407 | 0.633405 | 3 | 0 | 3 |
| FOCAD | RPS6 | 0.631643 | 7 | 0 | 5 |
| FOCAD | ZNF441 | 0.628631 | 3 | 0 | 3 |
| FOCAD | RBL2 | 0.610457 | 4 | 0 | 3 |
| FOCAD | CGNL1 | 0.605651 | 3 | 0 | 3 |
| FOCAD | SUSD4 | 0.601659 | 4 | 0 | 4 |
| FOCAD | DCTN3 | 0.59195 | 5 | 0 | 4 |
| FOCAD | KLHL9 | 0.591711 | 11 | 0 | 7 |
| FOCAD | ATMIN | 0.584992 | 5 | 0 | 4 |
| FOCAD | KDM4C | 0.582519 | 10 | 0 | 5 |
| FOCAD | SVIP | 0.581207 | 4 | 0 | 3 |
| FOCAD | CAAP1 | 0.576487 | 8 | 0 | 6 |
| FOCAD | SRR | 0.57542 | 3 | 0 | 3 |
| FOCAD | ALDH6A1 | 0.571296 | 6 | 0 | 4 |
| FOCAD | MED7 | 0.571289 | 5 | 0 | 3 |
| FOCAD | C1GALT1 | 0.569375 | 4 | 0 | 3 |
For details and further investigation, click here
