| Full name: sodium channel epithelial 1 delta subunit | Alias Symbol: ENaCdelta|dNaCh | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 6339 | HGNC ID: HGNC:10601 | Ensembl Gene: ENSG00000162572 | OMIM ID: 601328 |
| Drug and gene relationship at DGIdb | |||
Expression of SCNN1D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCNN1D | 6339 | 208458_at | -0.1395 | 0.5641 | |
| GSE20347 | SCNN1D | 6339 | 208458_at | 0.0581 | 0.5311 | |
| GSE23400 | SCNN1D | 6339 | 208458_at | -0.1182 | 0.0083 | |
| GSE26886 | SCNN1D | 6339 | 208458_at | 0.0586 | 0.7132 | |
| GSE29001 | SCNN1D | 6339 | 208458_at | -0.0971 | 0.4931 | |
| GSE38129 | SCNN1D | 6339 | 208458_at | -0.0397 | 0.6533 | |
| GSE45670 | SCNN1D | 6339 | 208458_at | 0.3870 | 0.0169 | |
| GSE53622 | SCNN1D | 6339 | 77273 | -0.4507 | 0.0000 | |
| GSE53624 | SCNN1D | 6339 | 77273 | -1.2847 | 0.0000 | |
| GSE63941 | SCNN1D | 6339 | 208458_at | 0.0428 | 0.8243 | |
| GSE77861 | SCNN1D | 6339 | 208458_at | -0.0244 | 0.9022 | |
| GSE97050 | SCNN1D | A_21_P0000941 | -0.1387 | 0.5480 | ||
| SRP064894 | SCNN1D | 6339 | RNAseq | 0.2014 | 0.5453 | |
| SRP133303 | SCNN1D | 6339 | RNAseq | -0.2393 | 0.2833 | |
| SRP159526 | SCNN1D | 6339 | RNAseq | 0.5881 | 0.3560 | |
| SRP193095 | SCNN1D | 6339 | RNAseq | 0.8046 | 0.0080 | |
| SRP219564 | SCNN1D | 6339 | RNAseq | 0.0397 | 0.9489 | |
| TCGA | SCNN1D | 6339 | RNAseq | 0.1971 | 0.3921 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SCNN1D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCNN1D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCNN1D | 6339 | 3 | 7 | 20 | |
| GSE20123 | SCNN1D | 6339 | 3 | 6 | 21 | |
| GSE43470 | SCNN1D | 6339 | 3 | 5 | 35 | |
| GSE46452 | SCNN1D | 6339 | 7 | 1 | 51 | |
| GSE47630 | SCNN1D | 6339 | 8 | 4 | 28 | |
| GSE54993 | SCNN1D | 6339 | 2 | 2 | 66 | |
| GSE54994 | SCNN1D | 6339 | 15 | 2 | 36 | |
| GSE60625 | SCNN1D | 6339 | 0 | 0 | 11 | |
| GSE74703 | SCNN1D | 6339 | 3 | 3 | 30 | |
| GSE74704 | SCNN1D | 6339 | 3 | 0 | 17 | |
| TCGA | SCNN1D | 6339 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of SCNN1D:
Generating mutation plots.
Highly correlated genes for SCNN1D:
Showing top 20/462 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCNN1D | BARHL2 | 0.846396 | 3 | 0 | 3 |
| SCNN1D | KRTAP19-1 | 0.817138 | 3 | 0 | 3 |
| SCNN1D | CCDC81 | 0.796458 | 3 | 0 | 3 |
| SCNN1D | TDGF1 | 0.771698 | 3 | 0 | 3 |
| SCNN1D | KIRREL2 | 0.765632 | 4 | 0 | 4 |
| SCNN1D | CDH23 | 0.763213 | 3 | 0 | 3 |
| SCNN1D | KRTAP6-1 | 0.761661 | 3 | 0 | 3 |
| SCNN1D | OR13G1 | 0.758387 | 3 | 0 | 3 |
| SCNN1D | OR2Z1 | 0.752253 | 3 | 0 | 3 |
| SCNN1D | CCDC114 | 0.751443 | 3 | 0 | 3 |
| SCNN1D | KRTAP20-1 | 0.744298 | 3 | 0 | 3 |
| SCNN1D | CLDN24 | 0.740816 | 3 | 0 | 3 |
| SCNN1D | CLRN2 | 0.738514 | 3 | 0 | 3 |
| SCNN1D | TEN1 | 0.736895 | 3 | 0 | 3 |
| SCNN1D | CLEC18C | 0.731225 | 3 | 0 | 3 |
| SCNN1D | ABCC6 | 0.729742 | 3 | 0 | 3 |
| SCNN1D | ZBTB45 | 0.7296 | 3 | 0 | 3 |
| SCNN1D | MRGPRE | 0.727422 | 3 | 0 | 3 |
| SCNN1D | KRTAP5-4 | 0.726328 | 3 | 0 | 3 |
| SCNN1D | KRTAP6-3 | 0.720464 | 3 | 0 | 3 |
For details and further investigation, click here
