| Full name: cadherin related 23 | Alias Symbol: CDHR23 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 64072 | HGNC ID: HGNC:13733 | Ensembl Gene: ENSG00000107736 | OMIM ID: 605516 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH23 | 64072 | 232845_at | -0.0810 | 0.8078 | |
| GSE26886 | CDH23 | 64072 | 232845_at | 0.3314 | 0.0274 | |
| GSE45670 | CDH23 | 64072 | 232845_at | 0.0104 | 0.9166 | |
| GSE53622 | CDH23 | 64072 | 8565 | 0.0151 | 0.9464 | |
| GSE53624 | CDH23 | 64072 | 62912 | -0.2544 | 0.0035 | |
| GSE63941 | CDH23 | 64072 | 232845_at | 0.0708 | 0.7733 | |
| GSE77861 | CDH23 | 64072 | 232845_at | -0.1271 | 0.4295 | |
| GSE97050 | CDH23 | 64072 | A_23_P364437 | -0.7635 | 0.2372 | |
| SRP064894 | CDH23 | 64072 | RNAseq | 0.2154 | 0.5798 | |
| SRP133303 | CDH23 | 64072 | RNAseq | -0.2090 | 0.5053 | |
| SRP159526 | CDH23 | 64072 | RNAseq | -0.2888 | 0.5134 | |
| SRP193095 | CDH23 | 64072 | RNAseq | 0.6606 | 0.0201 | |
| SRP219564 | CDH23 | 64072 | RNAseq | -0.4516 | 0.2877 | |
| TCGA | CDH23 | 64072 | RNAseq | -0.6681 | 0.0153 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDH23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH23 | 64072 | 2 | 5 | 23 | |
| GSE20123 | CDH23 | 64072 | 2 | 4 | 24 | |
| GSE43470 | CDH23 | 64072 | 1 | 8 | 34 | |
| GSE46452 | CDH23 | 64072 | 0 | 11 | 48 | |
| GSE47630 | CDH23 | 64072 | 2 | 14 | 24 | |
| GSE54993 | CDH23 | 64072 | 7 | 0 | 63 | |
| GSE54994 | CDH23 | 64072 | 2 | 12 | 39 | |
| GSE60625 | CDH23 | 64072 | 0 | 0 | 11 | |
| GSE74703 | CDH23 | 64072 | 1 | 5 | 30 | |
| GSE74704 | CDH23 | 64072 | 1 | 1 | 18 | |
| TCGA | CDH23 | 64072 | 11 | 23 | 62 |
Total number of gains: 29; Total number of losses: 83; Total Number of normals: 376.
Somatic mutations of CDH23:
Generating mutation plots.
Highly correlated genes for CDH23:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH23 | ZNF444 | 0.77322 | 3 | 0 | 3 |
| CDH23 | SCNN1D | 0.763213 | 3 | 0 | 3 |
| CDH23 | ADCY1 | 0.75661 | 3 | 0 | 3 |
| CDH23 | KCNQ4 | 0.752051 | 3 | 0 | 3 |
| CDH23 | TNXB | 0.745308 | 3 | 0 | 3 |
| CDH23 | LENG1 | 0.744763 | 3 | 0 | 3 |
| CDH23 | ARHGAP30 | 0.741544 | 3 | 0 | 3 |
| CDH23 | AIRE | 0.73937 | 3 | 0 | 3 |
| CDH23 | PTCRA | 0.731426 | 3 | 0 | 3 |
| CDH23 | SHISA4 | 0.730417 | 3 | 0 | 3 |
| CDH23 | NPPC | 0.729928 | 3 | 0 | 3 |
| CDH23 | ADM2 | 0.72617 | 4 | 0 | 3 |
| CDH23 | MIR146A | 0.725067 | 3 | 0 | 3 |
| CDH23 | C20orf141 | 0.717074 | 4 | 0 | 4 |
| CDH23 | NAPA-AS1 | 0.715143 | 3 | 0 | 3 |
| CDH23 | NOXA1 | 0.711915 | 4 | 0 | 3 |
| CDH23 | CHST8 | 0.707328 | 3 | 0 | 3 |
| CDH23 | INF2 | 0.706513 | 3 | 0 | 3 |
| CDH23 | SEMA3B | 0.70281 | 4 | 0 | 3 |
| CDH23 | RETN | 0.701496 | 4 | 0 | 3 |
For details and further investigation, click here
