| Full name: zinc finger and BTB domain containing 45 | Alias Symbol: FLJ14486 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 84878 | HGNC ID: HGNC:23715 | Ensembl Gene: ENSG00000119574 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB45:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB45 | 84878 | 229862_x_at | -0.1978 | 0.6402 | |
| GSE26886 | ZBTB45 | 84878 | 229862_x_at | 0.3838 | 0.0593 | |
| GSE45670 | ZBTB45 | 84878 | 229862_x_at | -0.1385 | 0.1677 | |
| GSE53622 | ZBTB45 | 84878 | 18079 | -0.1665 | 0.0001 | |
| GSE53624 | ZBTB45 | 84878 | 18079 | -0.1365 | 0.0097 | |
| GSE63941 | ZBTB45 | 84878 | 229862_x_at | -0.3806 | 0.1396 | |
| GSE77861 | ZBTB45 | 84878 | 229862_x_at | -0.2339 | 0.3705 | |
| GSE97050 | ZBTB45 | 84878 | A_23_P164623 | -0.0548 | 0.8087 | |
| SRP007169 | ZBTB45 | 84878 | RNAseq | -1.5611 | 0.0052 | |
| SRP008496 | ZBTB45 | 84878 | RNAseq | -0.9227 | 0.0088 | |
| SRP064894 | ZBTB45 | 84878 | RNAseq | 0.3018 | 0.2865 | |
| SRP133303 | ZBTB45 | 84878 | RNAseq | -0.1021 | 0.5814 | |
| SRP159526 | ZBTB45 | 84878 | RNAseq | -0.0187 | 0.9406 | |
| SRP193095 | ZBTB45 | 84878 | RNAseq | 0.0268 | 0.8409 | |
| SRP219564 | ZBTB45 | 84878 | RNAseq | -0.1622 | 0.4574 | |
| TCGA | ZBTB45 | 84878 | RNAseq | 0.0212 | 0.7552 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZBTB45 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB45:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB45 | 84878 | 2 | 5 | 23 | |
| GSE20123 | ZBTB45 | 84878 | 2 | 4 | 24 | |
| GSE43470 | ZBTB45 | 84878 | 3 | 9 | 31 | |
| GSE46452 | ZBTB45 | 84878 | 45 | 1 | 13 | |
| GSE47630 | ZBTB45 | 84878 | 7 | 6 | 27 | |
| GSE54993 | ZBTB45 | 84878 | 18 | 4 | 48 | |
| GSE54994 | ZBTB45 | 84878 | 5 | 12 | 36 | |
| GSE60625 | ZBTB45 | 84878 | 9 | 0 | 2 | |
| GSE74703 | ZBTB45 | 84878 | 3 | 6 | 27 | |
| GSE74704 | ZBTB45 | 84878 | 2 | 1 | 17 | |
| TCGA | ZBTB45 | 84878 | 20 | 19 | 57 |
Total number of gains: 116; Total number of losses: 67; Total Number of normals: 305.
Somatic mutations of ZBTB45:
Generating mutation plots.
Highly correlated genes for ZBTB45:
Showing top 20/126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB45 | TULP1 | 0.80173 | 3 | 0 | 3 |
| ZBTB45 | VILL | 0.772968 | 3 | 0 | 3 |
| ZBTB45 | LMAN1L | 0.768917 | 3 | 0 | 3 |
| ZBTB45 | PSPN | 0.767901 | 3 | 0 | 3 |
| ZBTB45 | TNR | 0.75064 | 3 | 0 | 3 |
| ZBTB45 | WDR45 | 0.735752 | 3 | 0 | 3 |
| ZBTB45 | ARHGAP30 | 0.731151 | 3 | 0 | 3 |
| ZBTB45 | SCNN1D | 0.7296 | 3 | 0 | 3 |
| ZBTB45 | TNNC2 | 0.728826 | 3 | 0 | 3 |
| ZBTB45 | HPS1 | 0.72719 | 3 | 0 | 3 |
| ZBTB45 | CTU1 | 0.725107 | 3 | 0 | 3 |
| ZBTB45 | SLC22A31 | 0.721414 | 3 | 0 | 3 |
| ZBTB45 | FAM71E1 | 0.709163 | 3 | 0 | 3 |
| ZBTB45 | LRFN2 | 0.707448 | 4 | 0 | 3 |
| ZBTB45 | PHKA2 | 0.704658 | 3 | 0 | 3 |
| ZBTB45 | ZNF526 | 0.702607 | 4 | 0 | 4 |
| ZBTB45 | MYLK2 | 0.699572 | 3 | 0 | 3 |
| ZBTB45 | DYRK1B | 0.699516 | 5 | 0 | 4 |
| ZBTB45 | TRIM17 | 0.699412 | 3 | 0 | 3 |
| ZBTB45 | SPACA3 | 0.691946 | 3 | 0 | 3 |
For details and further investigation, click here
