| Full name: keratin associated protein 6-3 | Alias Symbol: KAP6.3 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 337968 | HGNC ID: HGNC:18933 | Ensembl Gene: ENSG00000212938 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP6-3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP6-3 | 337968 | 38449 | -0.7470 | 0.0000 | |
| GSE53624 | KRTAP6-3 | 337968 | 38449 | -1.0204 | 0.0000 | |
| GSE97050 | KRTAP6-3 | 337968 | A_24_P391604 | -0.4211 | 0.2075 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRTAP6-3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP6-3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP6-3 | 337968 | 2 | 9 | 19 | |
| GSE20123 | KRTAP6-3 | 337968 | 2 | 9 | 19 | |
| GSE43470 | KRTAP6-3 | 337968 | 2 | 9 | 32 | |
| GSE46452 | KRTAP6-3 | 337968 | 1 | 21 | 37 | |
| GSE47630 | KRTAP6-3 | 337968 | 6 | 17 | 17 | |
| GSE54993 | KRTAP6-3 | 337968 | 9 | 1 | 60 | |
| GSE54994 | KRTAP6-3 | 337968 | 1 | 9 | 43 | |
| GSE60625 | KRTAP6-3 | 337968 | 0 | 0 | 11 | |
| GSE74703 | KRTAP6-3 | 337968 | 2 | 6 | 28 | |
| GSE74704 | KRTAP6-3 | 337968 | 2 | 6 | 12 |
Total number of gains: 27; Total number of losses: 87; Total Number of normals: 278.
Somatic mutations of KRTAP6-3:
Generating mutation plots.
Highly correlated genes for KRTAP6-3:
Showing top 20/87 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP6-3 | GATA4 | 0.744665 | 3 | 0 | 3 |
| KRTAP6-3 | GALNT9 | 0.733533 | 3 | 0 | 3 |
| KRTAP6-3 | SCNN1D | 0.720464 | 3 | 0 | 3 |
| KRTAP6-3 | C2orf73 | 0.720023 | 3 | 0 | 3 |
| KRTAP6-3 | TDGF1 | 0.718922 | 3 | 0 | 3 |
| KRTAP6-3 | CRHR1 | 0.710611 | 3 | 0 | 3 |
| KRTAP6-3 | KRTAP4-1 | 0.709365 | 3 | 0 | 3 |
| KRTAP6-3 | KRTAP20-1 | 0.703141 | 3 | 0 | 3 |
| KRTAP6-3 | OR2Z1 | 0.694774 | 3 | 0 | 3 |
| KRTAP6-3 | BTBD19 | 0.689858 | 3 | 0 | 3 |
| KRTAP6-3 | SLC4A3 | 0.689555 | 3 | 0 | 3 |
| KRTAP6-3 | GPT | 0.682441 | 3 | 0 | 3 |
| KRTAP6-3 | ADAM33 | 0.681961 | 3 | 0 | 3 |
| KRTAP6-3 | SRPK3 | 0.679119 | 3 | 0 | 3 |
| KRTAP6-3 | ALDH4A1 | 0.673311 | 3 | 0 | 3 |
| KRTAP6-3 | UPB1 | 0.671156 | 3 | 0 | 3 |
| KRTAP6-3 | MVK | 0.669301 | 3 | 0 | 3 |
| KRTAP6-3 | UCP3 | 0.669249 | 3 | 0 | 3 |
| KRTAP6-3 | MAP3K10 | 0.667343 | 3 | 0 | 3 |
| KRTAP6-3 | PRDM16 | 0.667165 | 3 | 0 | 3 |
For details and further investigation, click here
