| Full name: signal peptide, CUB domain and EGF like domain containing 2 | Alias Symbol: Cegf1|Cegb1|FLJ16792 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 57758 | HGNC ID: HGNC:30425 | Ensembl Gene: ENSG00000175356 | OMIM ID: 611747 |
| Drug and gene relationship at DGIdb | |||
Expression of SCUBE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCUBE2 | 57758 | 219197_s_at | -1.3936 | 0.0399 | |
| GSE20347 | SCUBE2 | 57758 | 219197_s_at | -0.3363 | 0.0712 | |
| GSE23400 | SCUBE2 | 57758 | 219197_s_at | -0.2082 | 0.0000 | |
| GSE26886 | SCUBE2 | 57758 | 219197_s_at | -0.5817 | 0.2677 | |
| GSE29001 | SCUBE2 | 57758 | 219197_s_at | -0.5359 | 0.0058 | |
| GSE38129 | SCUBE2 | 57758 | 219197_s_at | -0.7613 | 0.0009 | |
| GSE45670 | SCUBE2 | 57758 | 219197_s_at | -0.5121 | 0.0672 | |
| GSE53622 | SCUBE2 | 57758 | 12087 | -0.1588 | 0.4812 | |
| GSE53624 | SCUBE2 | 57758 | 12087 | -0.4746 | 0.0023 | |
| GSE63941 | SCUBE2 | 57758 | 219197_s_at | -1.1111 | 0.0011 | |
| GSE77861 | SCUBE2 | 57758 | 219197_s_at | -0.1600 | 0.5116 | |
| GSE97050 | SCUBE2 | 57758 | A_23_P105144 | -0.3014 | 0.4587 | |
| SRP064894 | SCUBE2 | 57758 | RNAseq | -0.6135 | 0.0640 | |
| SRP133303 | SCUBE2 | 57758 | RNAseq | -0.9204 | 0.0261 | |
| SRP159526 | SCUBE2 | 57758 | RNAseq | -1.0080 | 0.0010 | |
| SRP193095 | SCUBE2 | 57758 | RNAseq | -0.4589 | 0.1553 | |
| SRP219564 | SCUBE2 | 57758 | RNAseq | -0.8960 | 0.2421 | |
| TCGA | SCUBE2 | 57758 | RNAseq | -1.3067 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SCUBE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCUBE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCUBE2 | 57758 | 0 | 10 | 20 | |
| GSE20123 | SCUBE2 | 57758 | 0 | 10 | 20 | |
| GSE43470 | SCUBE2 | 57758 | 1 | 5 | 37 | |
| GSE46452 | SCUBE2 | 57758 | 7 | 5 | 47 | |
| GSE47630 | SCUBE2 | 57758 | 2 | 12 | 26 | |
| GSE54993 | SCUBE2 | 57758 | 3 | 1 | 66 | |
| GSE54994 | SCUBE2 | 57758 | 2 | 12 | 39 | |
| GSE60625 | SCUBE2 | 57758 | 0 | 0 | 11 | |
| GSE74703 | SCUBE2 | 57758 | 1 | 3 | 32 | |
| GSE74704 | SCUBE2 | 57758 | 0 | 8 | 12 | |
| TCGA | SCUBE2 | 57758 | 11 | 34 | 51 |
Total number of gains: 27; Total number of losses: 100; Total Number of normals: 361.
Somatic mutations of SCUBE2:
Generating mutation plots.
Highly correlated genes for SCUBE2:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCUBE2 | NKAPL | 0.765491 | 3 | 0 | 3 |
| SCUBE2 | SLC17A5 | 0.743463 | 4 | 0 | 4 |
| SCUBE2 | TMLHE | 0.727062 | 3 | 0 | 3 |
| SCUBE2 | ZNF528 | 0.721764 | 4 | 0 | 4 |
| SCUBE2 | WWOX | 0.713774 | 4 | 0 | 4 |
| SCUBE2 | SGMS2 | 0.711083 | 3 | 0 | 3 |
| SCUBE2 | ZNF10 | 0.702332 | 3 | 0 | 3 |
| SCUBE2 | PALLD | 0.697315 | 3 | 0 | 3 |
| SCUBE2 | KDM5D | 0.692479 | 3 | 0 | 3 |
| SCUBE2 | ZNF844 | 0.687469 | 5 | 0 | 4 |
| SCUBE2 | AIFM2 | 0.68607 | 3 | 0 | 3 |
| SCUBE2 | MOB4 | 0.684145 | 4 | 0 | 3 |
| SCUBE2 | THAP4 | 0.683501 | 3 | 0 | 3 |
| SCUBE2 | LRRC20 | 0.683006 | 3 | 0 | 3 |
| SCUBE2 | CLTA | 0.681744 | 3 | 0 | 3 |
| SCUBE2 | PDCD7 | 0.681657 | 3 | 0 | 3 |
| SCUBE2 | FAM120AOS | 0.678829 | 3 | 0 | 3 |
| SCUBE2 | STARD9 | 0.67738 | 3 | 0 | 3 |
| SCUBE2 | COG5 | 0.669947 | 3 | 0 | 3 |
| SCUBE2 | ARL2BP | 0.669648 | 4 | 0 | 4 |
For details and further investigation, click here
