| Full name: programmed cell death 7 | Alias Symbol: HES18|ES18 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 10081 | HGNC ID: HGNC:8767 | Ensembl Gene: ENSG00000090470 | OMIM ID: 608138 |
| Drug and gene relationship at DGIdb | |||
Expression of PDCD7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCD7 | 10081 | 231809_x_at | -0.5900 | 0.1425 | |
| GSE26886 | PDCD7 | 10081 | 231809_x_at | -0.6194 | 0.0126 | |
| GSE45670 | PDCD7 | 10081 | 231809_x_at | -0.1776 | 0.1592 | |
| GSE53622 | PDCD7 | 10081 | 144366 | -0.3309 | 0.0000 | |
| GSE53624 | PDCD7 | 10081 | 107834 | -0.3336 | 0.0000 | |
| GSE63941 | PDCD7 | 10081 | 231809_x_at | -0.7505 | 0.0135 | |
| GSE77861 | PDCD7 | 10081 | 231809_x_at | 0.0498 | 0.8710 | |
| GSE97050 | PDCD7 | 10081 | A_23_P129118 | -0.4295 | 0.1470 | |
| SRP007169 | PDCD7 | 10081 | RNAseq | -0.8988 | 0.0157 | |
| SRP008496 | PDCD7 | 10081 | RNAseq | -0.9671 | 0.0002 | |
| SRP064894 | PDCD7 | 10081 | RNAseq | -0.3597 | 0.0000 | |
| SRP133303 | PDCD7 | 10081 | RNAseq | -0.2354 | 0.1087 | |
| SRP159526 | PDCD7 | 10081 | RNAseq | -0.3720 | 0.1335 | |
| SRP193095 | PDCD7 | 10081 | RNAseq | -0.2119 | 0.0279 | |
| SRP219564 | PDCD7 | 10081 | RNAseq | -0.0403 | 0.9296 | |
| TCGA | PDCD7 | 10081 | RNAseq | 0.0116 | 0.8275 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDCD7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCD7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCD7 | 10081 | 7 | 3 | 20 | |
| GSE20123 | PDCD7 | 10081 | 7 | 3 | 20 | |
| GSE43470 | PDCD7 | 10081 | 4 | 6 | 33 | |
| GSE46452 | PDCD7 | 10081 | 3 | 7 | 49 | |
| GSE47630 | PDCD7 | 10081 | 8 | 10 | 22 | |
| GSE54993 | PDCD7 | 10081 | 5 | 6 | 59 | |
| GSE54994 | PDCD7 | 10081 | 6 | 7 | 40 | |
| GSE60625 | PDCD7 | 10081 | 4 | 0 | 7 | |
| GSE74703 | PDCD7 | 10081 | 4 | 3 | 29 | |
| GSE74704 | PDCD7 | 10081 | 3 | 3 | 14 | |
| TCGA | PDCD7 | 10081 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of PDCD7:
Generating mutation plots.
Highly correlated genes for PDCD7:
Showing top 20/468 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCD7 | PINK1 | 0.828508 | 4 | 0 | 4 |
| PDCD7 | TRIM6 | 0.793466 | 3 | 0 | 3 |
| PDCD7 | SAP18 | 0.780329 | 3 | 0 | 3 |
| PDCD7 | ZRANB1 | 0.770875 | 3 | 0 | 3 |
| PDCD7 | PGM1 | 0.755742 | 3 | 0 | 3 |
| PDCD7 | SGMS2 | 0.753286 | 4 | 0 | 4 |
| PDCD7 | BECN1 | 0.750977 | 3 | 0 | 3 |
| PDCD7 | KDSR | 0.746362 | 3 | 0 | 3 |
| PDCD7 | CD63 | 0.744056 | 3 | 0 | 3 |
| PDCD7 | NAA35 | 0.741418 | 3 | 0 | 3 |
| PDCD7 | PRICKLE2 | 0.740109 | 3 | 0 | 3 |
| PDCD7 | RPS27L | 0.738193 | 3 | 0 | 3 |
| PDCD7 | HMGCL | 0.735998 | 3 | 0 | 3 |
| PDCD7 | POLR2L | 0.733408 | 3 | 0 | 3 |
| PDCD7 | TMEM159 | 0.731538 | 3 | 0 | 3 |
| PDCD7 | INSIG1 | 0.730176 | 3 | 0 | 3 |
| PDCD7 | ATAD1 | 0.729865 | 3 | 0 | 3 |
| PDCD7 | USP47 | 0.728698 | 5 | 0 | 4 |
| PDCD7 | UBE2G2 | 0.726756 | 4 | 0 | 3 |
| PDCD7 | SLTM | 0.723624 | 6 | 0 | 6 |
For details and further investigation, click here
