| Full name: component of oligomeric golgi complex 5 | Alias Symbol: GTC90 | ||
| Type: protein-coding gene | Cytoband: 7q22.3 | ||
| Entrez ID: 10466 | HGNC ID: HGNC:14857 | Ensembl Gene: ENSG00000164597 | OMIM ID: 606821 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG5 | 10466 | 203630_s_at | -0.4437 | 0.4038 | |
| GSE20347 | COG5 | 10466 | 203629_s_at | -0.0486 | 0.7841 | |
| GSE23400 | COG5 | 10466 | 203630_s_at | 0.1240 | 0.2021 | |
| GSE26886 | COG5 | 10466 | 203630_s_at | -0.3029 | 0.1371 | |
| GSE29001 | COG5 | 10466 | 203630_s_at | -0.0067 | 0.9761 | |
| GSE38129 | COG5 | 10466 | 203630_s_at | 0.1869 | 0.1383 | |
| GSE45670 | COG5 | 10466 | 203630_s_at | 0.0567 | 0.7522 | |
| GSE53622 | COG5 | 10466 | 51668 | 0.1175 | 0.0423 | |
| GSE53624 | COG5 | 10466 | 51668 | 0.0904 | 0.1062 | |
| GSE63941 | COG5 | 10466 | 203630_s_at | 0.2335 | 0.6294 | |
| GSE77861 | COG5 | 10466 | 203629_s_at | -0.3618 | 0.0759 | |
| GSE97050 | COG5 | 10466 | A_23_P134614 | 0.1707 | 0.5564 | |
| SRP007169 | COG5 | 10466 | RNAseq | -0.5753 | 0.0622 | |
| SRP008496 | COG5 | 10466 | RNAseq | -0.6256 | 0.0003 | |
| SRP064894 | COG5 | 10466 | RNAseq | -0.3789 | 0.0340 | |
| SRP133303 | COG5 | 10466 | RNAseq | 0.0873 | 0.4754 | |
| SRP159526 | COG5 | 10466 | RNAseq | -0.3604 | 0.2116 | |
| SRP193095 | COG5 | 10466 | RNAseq | -0.1374 | 0.2197 | |
| SRP219564 | COG5 | 10466 | RNAseq | -0.1790 | 0.5663 | |
| TCGA | COG5 | 10466 | RNAseq | 0.0196 | 0.6978 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COG5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COG5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG5 | 10466 | 12 | 0 | 18 | |
| GSE20123 | COG5 | 10466 | 12 | 0 | 18 | |
| GSE43470 | COG5 | 10466 | 6 | 2 | 35 | |
| GSE46452 | COG5 | 10466 | 10 | 1 | 48 | |
| GSE47630 | COG5 | 10466 | 8 | 3 | 29 | |
| GSE54993 | COG5 | 10466 | 2 | 9 | 59 | |
| GSE54994 | COG5 | 10466 | 16 | 4 | 33 | |
| GSE60625 | COG5 | 10466 | 0 | 0 | 11 | |
| GSE74703 | COG5 | 10466 | 6 | 2 | 28 | |
| GSE74704 | COG5 | 10466 | 8 | 0 | 12 | |
| TCGA | COG5 | 10466 | 49 | 11 | 36 |
Total number of gains: 129; Total number of losses: 32; Total Number of normals: 327.
Somatic mutations of COG5:
Generating mutation plots.
Highly correlated genes for COG5:
Showing top 20/385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG5 | SAMD9L | 0.815923 | 3 | 0 | 3 |
| COG5 | PDLIM5 | 0.776955 | 3 | 0 | 3 |
| COG5 | TMEM219 | 0.774351 | 3 | 0 | 3 |
| COG5 | VPS37B | 0.764671 | 3 | 0 | 3 |
| COG5 | PEX11B | 0.751122 | 3 | 0 | 3 |
| COG5 | FBXL3 | 0.74167 | 3 | 0 | 3 |
| COG5 | NIPSNAP3A | 0.737083 | 3 | 0 | 3 |
| COG5 | MORC3 | 0.73622 | 3 | 0 | 3 |
| COG5 | PRADC1 | 0.733293 | 3 | 0 | 3 |
| COG5 | RABGAP1L | 0.726408 | 3 | 0 | 3 |
| COG5 | APPL1 | 0.726162 | 4 | 0 | 3 |
| COG5 | XYLT1 | 0.723784 | 3 | 0 | 3 |
| COG5 | CRYBG3 | 0.723776 | 4 | 0 | 4 |
| COG5 | ENDOD1 | 0.723611 | 3 | 0 | 3 |
| COG5 | CRYL1 | 0.723072 | 3 | 0 | 3 |
| COG5 | WDFY1 | 0.719683 | 3 | 0 | 3 |
| COG5 | PARP4 | 0.718238 | 3 | 0 | 3 |
| COG5 | RSBN1 | 0.717307 | 3 | 0 | 3 |
| COG5 | SOS1 | 0.717065 | 3 | 0 | 3 |
| COG5 | RNLS | 0.714883 | 4 | 0 | 4 |
For details and further investigation, click here
