| Full name: solute carrier family 17 member 5 | Alias Symbol: AST|SD|ISSD|NSD|SIALIN|SLD | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 26503 | HGNC ID: HGNC:10933 | Ensembl Gene: ENSG00000119899 | OMIM ID: 604322 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC17A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC17A5 | 26503 | 223441_at | -0.7347 | 0.1060 | |
| GSE20347 | SLC17A5 | 26503 | 221041_s_at | -0.6274 | 0.0000 | |
| GSE23400 | SLC17A5 | 26503 | 221041_s_at | -0.2031 | 0.0000 | |
| GSE26886 | SLC17A5 | 26503 | 223441_at | -0.3819 | 0.1893 | |
| GSE29001 | SLC17A5 | 26503 | 221041_s_at | -0.4177 | 0.0213 | |
| GSE38129 | SLC17A5 | 26503 | 221041_s_at | -0.5440 | 0.0000 | |
| GSE45670 | SLC17A5 | 26503 | 223441_at | -0.6392 | 0.0007 | |
| GSE53622 | SLC17A5 | 26503 | 128203 | -0.4979 | 0.0000 | |
| GSE53624 | SLC17A5 | 26503 | 101572 | -0.7818 | 0.0000 | |
| GSE63941 | SLC17A5 | 26503 | 223441_at | -2.7230 | 0.0007 | |
| GSE77861 | SLC17A5 | 26503 | 223441_at | -0.5258 | 0.1161 | |
| GSE97050 | SLC17A5 | 26503 | A_33_P3265270 | -0.1055 | 0.6490 | |
| SRP007169 | SLC17A5 | 26503 | RNAseq | -0.7507 | 0.0214 | |
| SRP008496 | SLC17A5 | 26503 | RNAseq | -0.8046 | 0.0036 | |
| SRP064894 | SLC17A5 | 26503 | RNAseq | -0.4565 | 0.0713 | |
| SRP133303 | SLC17A5 | 26503 | RNAseq | -0.1632 | 0.3425 | |
| SRP159526 | SLC17A5 | 26503 | RNAseq | -0.5349 | 0.1068 | |
| SRP193095 | SLC17A5 | 26503 | RNAseq | -0.8139 | 0.0000 | |
| SRP219564 | SLC17A5 | 26503 | RNAseq | -0.3157 | 0.4076 | |
| TCGA | SLC17A5 | 26503 | RNAseq | -0.3770 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC17A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC17A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC17A5 | 26503 | 1 | 3 | 26 | |
| GSE20123 | SLC17A5 | 26503 | 1 | 2 | 27 | |
| GSE43470 | SLC17A5 | 26503 | 3 | 0 | 40 | |
| GSE46452 | SLC17A5 | 26503 | 2 | 11 | 46 | |
| GSE47630 | SLC17A5 | 26503 | 8 | 4 | 28 | |
| GSE54993 | SLC17A5 | 26503 | 3 | 2 | 65 | |
| GSE54994 | SLC17A5 | 26503 | 8 | 9 | 36 | |
| GSE60625 | SLC17A5 | 26503 | 0 | 1 | 10 | |
| GSE74703 | SLC17A5 | 26503 | 3 | 0 | 33 | |
| GSE74704 | SLC17A5 | 26503 | 0 | 1 | 19 | |
| TCGA | SLC17A5 | 26503 | 11 | 21 | 64 |
Total number of gains: 40; Total number of losses: 54; Total Number of normals: 394.
Somatic mutations of SLC17A5:
Generating mutation plots.
Highly correlated genes for SLC17A5:
Showing top 20/1224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC17A5 | FAM160B1 | 0.788271 | 3 | 0 | 3 |
| SLC17A5 | ANKHD1 | 0.771464 | 3 | 0 | 3 |
| SLC17A5 | CPE | 0.748574 | 3 | 0 | 3 |
| SLC17A5 | ANKRD37 | 0.744648 | 3 | 0 | 3 |
| SLC17A5 | SCUBE2 | 0.743463 | 4 | 0 | 4 |
| SLC17A5 | GPR108 | 0.729827 | 3 | 0 | 3 |
| SLC17A5 | DOK6 | 0.727625 | 4 | 0 | 4 |
| SLC17A5 | IP6K1 | 0.724569 | 3 | 0 | 3 |
| SLC17A5 | ARRDC3 | 0.717216 | 5 | 0 | 5 |
| SLC17A5 | SCARB2 | 0.711654 | 3 | 0 | 3 |
| SLC17A5 | TRAM1 | 0.708735 | 4 | 0 | 3 |
| SLC17A5 | RHBDF1 | 0.708296 | 4 | 0 | 4 |
| SLC17A5 | RPL41 | 0.707971 | 3 | 0 | 3 |
| SLC17A5 | SKI | 0.707481 | 3 | 0 | 3 |
| SLC17A5 | DCTN3 | 0.707312 | 5 | 0 | 4 |
| SLC17A5 | IBTK | 0.694814 | 7 | 0 | 6 |
| SLC17A5 | RGS14 | 0.69061 | 4 | 0 | 4 |
| SLC17A5 | VPS29 | 0.68999 | 4 | 0 | 3 |
| SLC17A5 | TBC1D20 | 0.685661 | 4 | 0 | 3 |
| SLC17A5 | MMADHC | 0.685625 | 4 | 0 | 4 |
For details and further investigation, click here
