| Full name: NFKB activating protein like | Alias Symbol: bA424I5.1 | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 222698 | HGNC ID: HGNC:21584 | Ensembl Gene: ENSG00000189134 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NKAPL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NKAPL | 222698 | 229340_at | -0.2786 | 0.3184 | |
| GSE26886 | NKAPL | 222698 | 229340_at | -0.1587 | 0.4289 | |
| GSE45670 | NKAPL | 222698 | 229340_at | -0.3296 | 0.0071 | |
| GSE53622 | NKAPL | 222698 | 57822 | -0.6066 | 0.0000 | |
| GSE53624 | NKAPL | 222698 | 57822 | -0.2400 | 0.0093 | |
| GSE63941 | NKAPL | 222698 | 229340_at | -0.9252 | 0.0001 | |
| GSE77861 | NKAPL | 222698 | 229340_at | -0.2308 | 0.0993 | |
| GSE97050 | NKAPL | 222698 | A_33_P3417880 | -0.2343 | 0.4399 | |
| SRP159526 | NKAPL | 222698 | RNAseq | -1.6405 | 0.0047 | |
| TCGA | NKAPL | 222698 | RNAseq | -1.4928 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NKAPL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NKAPL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NKAPL | 222698 | 3 | 2 | 25 | |
| GSE20123 | NKAPL | 222698 | 3 | 2 | 25 | |
| GSE43470 | NKAPL | 222698 | 5 | 0 | 38 | |
| GSE46452 | NKAPL | 222698 | 1 | 10 | 48 | |
| GSE47630 | NKAPL | 222698 | 7 | 4 | 29 | |
| GSE54993 | NKAPL | 222698 | 2 | 1 | 67 | |
| GSE54994 | NKAPL | 222698 | 11 | 4 | 38 | |
| GSE60625 | NKAPL | 222698 | 0 | 1 | 10 | |
| GSE74703 | NKAPL | 222698 | 5 | 0 | 31 | |
| GSE74704 | NKAPL | 222698 | 0 | 1 | 19 | |
| TCGA | NKAPL | 222698 | 15 | 19 | 62 |
Total number of gains: 52; Total number of losses: 44; Total Number of normals: 392.
Somatic mutations of NKAPL:
Generating mutation plots.
Highly correlated genes for NKAPL:
Showing top 20/803 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NKAPL | MRGPRF | 0.849308 | 3 | 0 | 3 |
| NKAPL | C11orf96 | 0.822398 | 3 | 0 | 3 |
| NKAPL | PDGFRA | 0.809185 | 4 | 0 | 4 |
| NKAPL | ACTG2 | 0.805223 | 4 | 0 | 4 |
| NKAPL | PJA2 | 0.803176 | 3 | 0 | 3 |
| NKAPL | PDE5A | 0.794943 | 4 | 0 | 4 |
| NKAPL | SOX17 | 0.792369 | 3 | 0 | 3 |
| NKAPL | LSM11 | 0.788348 | 3 | 0 | 3 |
| NKAPL | BMPR1A | 0.782678 | 3 | 0 | 3 |
| NKAPL | ZEB2 | 0.775443 | 4 | 0 | 4 |
| NKAPL | GPRASP1 | 0.770237 | 4 | 0 | 4 |
| NKAPL | THRB | 0.768784 | 3 | 0 | 3 |
| NKAPL | DMD | 0.768686 | 3 | 0 | 3 |
| NKAPL | SATB1 | 0.76822 | 3 | 0 | 3 |
| NKAPL | SCUBE2 | 0.765491 | 3 | 0 | 3 |
| NKAPL | JAM3 | 0.760991 | 4 | 0 | 4 |
| NKAPL | ITIH5 | 0.760139 | 3 | 0 | 3 |
| NKAPL | STARD13 | 0.758609 | 3 | 0 | 3 |
| NKAPL | SCARB2 | 0.753313 | 3 | 0 | 3 |
| NKAPL | KANK2 | 0.753116 | 5 | 0 | 5 |
For details and further investigation, click here
