| Full name: THAP domain containing 4 | Alias Symbol: CGI-36|Nb(III) | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 51078 | HGNC ID: HGNC:23187 | Ensembl Gene: ENSG00000176946 | OMIM ID: 612533 |
| Drug and gene relationship at DGIdb | |||
Expression of THAP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP4 | 51078 | 224057_s_at | -0.4015 | 0.2708 | |
| GSE20347 | THAP4 | 51078 | 220417_s_at | -0.3839 | 0.0121 | |
| GSE23400 | THAP4 | 51078 | 220417_s_at | -0.2174 | 0.0002 | |
| GSE26886 | THAP4 | 51078 | 224057_s_at | 0.3378 | 0.0290 | |
| GSE29001 | THAP4 | 51078 | 220417_s_at | 0.0227 | 0.9404 | |
| GSE38129 | THAP4 | 51078 | 220417_s_at | -0.3216 | 0.0061 | |
| GSE45670 | THAP4 | 51078 | 224057_s_at | -0.1563 | 0.2748 | |
| GSE53622 | THAP4 | 51078 | 84139 | -0.2730 | 0.0001 | |
| GSE53624 | THAP4 | 51078 | 84139 | -0.2898 | 0.0000 | |
| GSE63941 | THAP4 | 51078 | 224057_s_at | -0.0660 | 0.8887 | |
| GSE77861 | THAP4 | 51078 | 220417_s_at | -0.0925 | 0.6093 | |
| GSE97050 | THAP4 | 51078 | A_23_P84782 | 0.1669 | 0.5375 | |
| SRP007169 | THAP4 | 51078 | RNAseq | 0.0238 | 0.9660 | |
| SRP008496 | THAP4 | 51078 | RNAseq | 0.4107 | 0.2759 | |
| SRP064894 | THAP4 | 51078 | RNAseq | 0.0283 | 0.9354 | |
| SRP133303 | THAP4 | 51078 | RNAseq | -0.0461 | 0.7241 | |
| SRP159526 | THAP4 | 51078 | RNAseq | -0.0294 | 0.9013 | |
| SRP193095 | THAP4 | 51078 | RNAseq | -0.4944 | 0.0000 | |
| SRP219564 | THAP4 | 51078 | RNAseq | -0.0517 | 0.8480 | |
| TCGA | THAP4 | 51078 | RNAseq | 0.0230 | 0.6306 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP4 | 51078 | 1 | 12 | 17 | |
| GSE20123 | THAP4 | 51078 | 1 | 12 | 17 | |
| GSE43470 | THAP4 | 51078 | 1 | 9 | 33 | |
| GSE46452 | THAP4 | 51078 | 0 | 5 | 54 | |
| GSE47630 | THAP4 | 51078 | 4 | 5 | 31 | |
| GSE54993 | THAP4 | 51078 | 4 | 3 | 63 | |
| GSE54994 | THAP4 | 51078 | 8 | 9 | 36 | |
| GSE60625 | THAP4 | 51078 | 0 | 3 | 8 | |
| GSE74703 | THAP4 | 51078 | 1 | 7 | 28 | |
| GSE74704 | THAP4 | 51078 | 1 | 5 | 14 | |
| TCGA | THAP4 | 51078 | 11 | 29 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of THAP4:
Generating mutation plots.
Highly correlated genes for THAP4:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP4 | RSRC2 | 0.773665 | 3 | 0 | 3 |
| THAP4 | FTSJ3 | 0.766526 | 3 | 0 | 3 |
| THAP4 | ECD | 0.755592 | 3 | 0 | 3 |
| THAP4 | MEA1 | 0.752486 | 3 | 0 | 3 |
| THAP4 | SARNP | 0.748758 | 3 | 0 | 3 |
| THAP4 | PDAP1 | 0.726122 | 4 | 0 | 4 |
| THAP4 | UTP14A | 0.713486 | 3 | 0 | 3 |
| THAP4 | FAM192A | 0.705822 | 3 | 0 | 3 |
| THAP4 | ACY1 | 0.704426 | 3 | 0 | 3 |
| THAP4 | PAQR4 | 0.69939 | 3 | 0 | 3 |
| THAP4 | ADAD2 | 0.693024 | 3 | 0 | 3 |
| THAP4 | RNF207 | 0.687746 | 3 | 0 | 3 |
| THAP4 | WHAMM | 0.684808 | 3 | 0 | 3 |
| THAP4 | HEMK1 | 0.683761 | 4 | 0 | 3 |
| THAP4 | SCUBE2 | 0.683501 | 3 | 0 | 3 |
| THAP4 | TACC2 | 0.683312 | 4 | 0 | 4 |
| THAP4 | DPP8 | 0.682321 | 3 | 0 | 3 |
| THAP4 | CBLL1 | 0.677535 | 3 | 0 | 3 |
| THAP4 | BCCIP | 0.677225 | 3 | 0 | 3 |
| THAP4 | THOC5 | 0.675563 | 3 | 0 | 3 |
For details and further investigation, click here
