| Full name: leucine rich repeat containing 20 | Alias Symbol: FLJ10751|FLJ10844 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 55222 | HGNC ID: HGNC:23421 | Ensembl Gene: ENSG00000172731 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC20 | 55222 | 218550_s_at | -0.7328 | 0.0666 | |
| GSE20347 | LRRC20 | 55222 | 218550_s_at | -0.5247 | 0.0064 | |
| GSE23400 | LRRC20 | 55222 | 218550_s_at | -0.4544 | 0.0000 | |
| GSE26886 | LRRC20 | 55222 | 218550_s_at | -1.2889 | 0.0010 | |
| GSE29001 | LRRC20 | 55222 | 218550_s_at | -0.9739 | 0.0010 | |
| GSE38129 | LRRC20 | 55222 | 218550_s_at | -0.5086 | 0.0037 | |
| GSE45670 | LRRC20 | 55222 | 218550_s_at | -0.2703 | 0.3957 | |
| GSE63941 | LRRC20 | 55222 | 218550_s_at | 0.6144 | 0.2518 | |
| GSE77861 | LRRC20 | 55222 | 218550_s_at | -0.4031 | 0.0366 | |
| GSE97050 | LRRC20 | 55222 | A_23_P61487 | -1.0359 | 0.0631 | |
| SRP007169 | LRRC20 | 55222 | RNAseq | -4.7033 | 0.0000 | |
| SRP008496 | LRRC20 | 55222 | RNAseq | -4.2770 | 0.0000 | |
| SRP064894 | LRRC20 | 55222 | RNAseq | -2.5830 | 0.0000 | |
| SRP133303 | LRRC20 | 55222 | RNAseq | -1.5019 | 0.0000 | |
| SRP159526 | LRRC20 | 55222 | RNAseq | -2.4041 | 0.0000 | |
| SRP193095 | LRRC20 | 55222 | RNAseq | -2.4143 | 0.0000 | |
| SRP219564 | LRRC20 | 55222 | RNAseq | -2.4713 | 0.0000 | |
| TCGA | LRRC20 | 55222 | RNAseq | -0.1149 | 0.2859 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by LRRC20 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LRRC20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC20 | 55222 | 2 | 4 | 24 | |
| GSE20123 | LRRC20 | 55222 | 2 | 3 | 25 | |
| GSE43470 | LRRC20 | 55222 | 1 | 7 | 35 | |
| GSE46452 | LRRC20 | 55222 | 0 | 11 | 48 | |
| GSE47630 | LRRC20 | 55222 | 2 | 14 | 24 | |
| GSE54993 | LRRC20 | 55222 | 7 | 0 | 63 | |
| GSE54994 | LRRC20 | 55222 | 2 | 12 | 39 | |
| GSE60625 | LRRC20 | 55222 | 0 | 0 | 11 | |
| GSE74703 | LRRC20 | 55222 | 1 | 4 | 31 | |
| GSE74704 | LRRC20 | 55222 | 1 | 1 | 18 | |
| TCGA | LRRC20 | 55222 | 9 | 23 | 64 |
Total number of gains: 27; Total number of losses: 79; Total Number of normals: 382.
Somatic mutations of LRRC20:
Generating mutation plots.
Highly correlated genes for LRRC20:
Showing top 20/981 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC20 | ATP6V1C2 | 0.778644 | 4 | 0 | 4 |
| LRRC20 | ANKRD37 | 0.77525 | 5 | 0 | 5 |
| LRRC20 | HCG22 | 0.772597 | 4 | 0 | 4 |
| LRRC20 | SFTA2 | 0.752264 | 4 | 0 | 4 |
| LRRC20 | LDHD | 0.748288 | 4 | 0 | 4 |
| LRRC20 | UTRN | 0.744922 | 3 | 0 | 3 |
| LRRC20 | SESN2 | 0.743066 | 5 | 0 | 5 |
| LRRC20 | SLC46A2 | 0.741374 | 5 | 0 | 5 |
| LRRC20 | MMEL1 | 0.739233 | 4 | 0 | 4 |
| LRRC20 | FAM214A | 0.738842 | 4 | 0 | 4 |
| LRRC20 | GYS2 | 0.737314 | 8 | 0 | 8 |
| LRRC20 | PAQR8 | 0.73511 | 5 | 0 | 5 |
| LRRC20 | LINC01214 | 0.729361 | 4 | 0 | 4 |
| LRRC20 | FAM13C | 0.72586 | 4 | 0 | 3 |
| LRRC20 | FAM95B1 | 0.723514 | 4 | 0 | 4 |
| LRRC20 | SPINK7 | 0.72069 | 4 | 0 | 4 |
| LRRC20 | FCHO2 | 0.718788 | 5 | 0 | 5 |
| LRRC20 | MAB21L3 | 0.717297 | 4 | 0 | 4 |
| LRRC20 | AIFM2 | 0.714759 | 4 | 0 | 3 |
| LRRC20 | C18orf25 | 0.714151 | 9 | 0 | 8 |
For details and further investigation, click here
