| Full name: serine incorporator 1 | Alias Symbol: TMS-2|TDE1L|KIAA1253 | ||
| Type: protein-coding gene | Cytoband: 6q22.31 | ||
| Entrez ID: 57515 | HGNC ID: HGNC:13464 | Ensembl Gene: ENSG00000111897 | OMIM ID: 614548 |
| Drug and gene relationship at DGIdb | |||
Expression of SERINC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERINC1 | 57515 | 208671_at | -0.9139 | 0.0386 | |
| GSE20347 | SERINC1 | 57515 | 208671_at | -0.6681 | 0.0004 | |
| GSE23400 | SERINC1 | 57515 | 208671_at | -0.1312 | 0.1742 | |
| GSE26886 | SERINC1 | 57515 | 208671_at | -0.8030 | 0.0035 | |
| GSE29001 | SERINC1 | 57515 | 208671_at | -0.4515 | 0.3528 | |
| GSE38129 | SERINC1 | 57515 | 208671_at | -0.6487 | 0.0008 | |
| GSE45670 | SERINC1 | 57515 | 208671_at | -0.6486 | 0.0000 | |
| GSE53622 | SERINC1 | 57515 | 32910 | -0.4829 | 0.0000 | |
| GSE53624 | SERINC1 | 57515 | 32910 | -0.3608 | 0.0000 | |
| GSE63941 | SERINC1 | 57515 | 208671_at | -1.8583 | 0.0003 | |
| GSE77861 | SERINC1 | 57515 | 208671_at | -0.1298 | 0.7290 | |
| GSE97050 | SERINC1 | 57515 | A_24_P129232 | -0.5310 | 0.1403 | |
| SRP007169 | SERINC1 | 57515 | RNAseq | -0.5209 | 0.0555 | |
| SRP008496 | SERINC1 | 57515 | RNAseq | -0.3144 | 0.0383 | |
| SRP064894 | SERINC1 | 57515 | RNAseq | -0.0729 | 0.7707 | |
| SRP133303 | SERINC1 | 57515 | RNAseq | 0.0010 | 0.9951 | |
| SRP159526 | SERINC1 | 57515 | RNAseq | -0.3345 | 0.2598 | |
| SRP193095 | SERINC1 | 57515 | RNAseq | -0.3280 | 0.0159 | |
| SRP219564 | SERINC1 | 57515 | RNAseq | -0.3267 | 0.4851 | |
| TCGA | SERINC1 | 57515 | RNAseq | -0.2058 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SERINC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERINC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERINC1 | 57515 | 1 | 4 | 25 | |
| GSE20123 | SERINC1 | 57515 | 1 | 3 | 26 | |
| GSE43470 | SERINC1 | 57515 | 5 | 1 | 37 | |
| GSE46452 | SERINC1 | 57515 | 2 | 11 | 46 | |
| GSE47630 | SERINC1 | 57515 | 9 | 4 | 27 | |
| GSE54993 | SERINC1 | 57515 | 3 | 2 | 65 | |
| GSE54994 | SERINC1 | 57515 | 8 | 8 | 37 | |
| GSE60625 | SERINC1 | 57515 | 0 | 1 | 10 | |
| GSE74703 | SERINC1 | 57515 | 4 | 1 | 31 | |
| GSE74704 | SERINC1 | 57515 | 0 | 1 | 19 | |
| TCGA | SERINC1 | 57515 | 10 | 18 | 68 |
Total number of gains: 43; Total number of losses: 54; Total Number of normals: 391.
Somatic mutations of SERINC1:
Generating mutation plots.
Highly correlated genes for SERINC1:
Showing top 20/1249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERINC1 | PITPNM3 | 0.823789 | 3 | 0 | 3 |
| SERINC1 | FIBIN | 0.784044 | 4 | 0 | 4 |
| SERINC1 | PARD3B | 0.773696 | 4 | 0 | 4 |
| SERINC1 | MYOCD | 0.772268 | 5 | 0 | 5 |
| SERINC1 | NKTR | 0.760863 | 3 | 0 | 3 |
| SERINC1 | C1QTNF7 | 0.760251 | 5 | 0 | 5 |
| SERINC1 | GOPC | 0.749388 | 3 | 0 | 3 |
| SERINC1 | MYADM | 0.74787 | 3 | 0 | 3 |
| SERINC1 | BTBD7 | 0.746703 | 3 | 0 | 3 |
| SERINC1 | SLIT3 | 0.746446 | 5 | 0 | 5 |
| SERINC1 | TMEM181 | 0.744803 | 3 | 0 | 3 |
| SERINC1 | FNIP2 | 0.738986 | 4 | 0 | 4 |
| SERINC1 | STARD9 | 0.736449 | 5 | 0 | 5 |
| SERINC1 | TCEAL6 | 0.732763 | 3 | 0 | 3 |
| SERINC1 | LRRN4CL | 0.729837 | 6 | 0 | 5 |
| SERINC1 | SNX18 | 0.728886 | 3 | 0 | 3 |
| SERINC1 | ZBTB47 | 0.727848 | 3 | 0 | 3 |
| SERINC1 | TCEAL5 | 0.727326 | 3 | 0 | 3 |
| SERINC1 | IDI1 | 0.726137 | 3 | 0 | 3 |
| SERINC1 | AKAP11 | 0.724228 | 11 | 0 | 11 |
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