PITPNM3

 

Full name: PITPNM family member 3 Alias Symbol: NIR1|RDGBA3|ACKR6
Type: protein-coding gene Cytoband: 17p13.2-p13.1
Entrez ID: 83394 HGNC ID: HGNC:21043 Ensembl Gene: ENSG00000091622 OMIM ID: 608921
Drug and gene relationship at DGIdb

 

Expression of PITPNM3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PITPNM3 83394 230076_at -0.7975 0.1886
GSE20347 PITPNM3 83394 221254_s_at -0.1161 0.0756
GSE23400 PITPNM3 83394 221254_s_at -0.1520 0.0002
GSE26886 PITPNM3 83394 230076_at -1.3333 0.0000
GSE29001 PITPNM3 83394 221254_s_at -0.1838 0.1881
GSE38129 PITPNM3 83394 221254_s_at -0.1320 0.0181
GSE45670 PITPNM3 83394 230076_at -0.5473 0.0379
GSE53622 PITPNM3 83394 61285 -1.3093 0.0000
GSE53624 PITPNM3 83394 61285 -1.2282 0.0000
GSE63941 PITPNM3 83394 230076_at 1.7093 0.0074
GSE77861 PITPNM3 83394 230076_at -0.3964 0.2544
GSE97050 PITPNM3 83394 A_33_P3342561 -1.3230 0.0737
SRP007169 PITPNM3 83394 RNAseq -0.2845 0.6098
SRP008496 PITPNM3 83394 RNAseq -0.4435 0.2462
SRP064894 PITPNM3 83394 RNAseq -1.4206 0.0000
SRP133303 PITPNM3 83394 RNAseq -1.3924 0.0000
SRP159526 PITPNM3 83394 RNAseq -1.2278 0.0039
SRP193095 PITPNM3 83394 RNAseq -1.0884 0.0000
SRP219564 PITPNM3 83394 RNAseq -0.9264 0.0906
TCGA PITPNM3 83394 RNAseq -0.2140 0.0801

Upregulated datasets: 1; Downregulated datasets: 7.  


 

Survival by PITPNM3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PITPNM3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PITPNM3 83394 4 2 24
GSE20123 PITPNM3 83394 4 3 23
GSE43470 PITPNM3 83394 1 6 36
GSE46452 PITPNM3 83394 34 1 24
GSE47630 PITPNM3 83394 7 1 32
GSE54993 PITPNM3 83394 4 3 63
GSE54994 PITPNM3 83394 5 8 40
GSE60625 PITPNM3 83394 4 0 7
GSE74703 PITPNM3 83394 1 3 32
GSE74704 PITPNM3 83394 2 1 17

Total number of gains: 66; Total number of losses: 28; Total Number of normals: 298.  


 

Somatic mutations of PITPNM3:

 

Generating mutation plots.

 

Highly correlated genes for PITPNM3:

 

Showing top 20/989 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PITPNM3SERINC10.823789303
PITPNM3HSPA20.778031303
PITPNM3RNF140.771447303
PITPNM3KDM3B0.765044303
PITPNM3MTA30.752469303
PITPNM3MYO9A0.746446303
PITPNM3UGP20.744227403
PITPNM3MIER30.741825303
PITPNM3CRYZ0.719645303
PITPNM3CUL50.719619303
PITPNM3EXD20.716009403
PITPNM3DCTN40.714659303
PITPNM3AKIP10.713998303
PITPNM3LYRM70.713295504
PITPNM3FAM8A10.712391403
PITPNM3ABLIM20.710262404
PITPNM3CGGBP10.706652403
PITPNM3PEX190.704175303
PITPNM3TMEM1590.701327606
PITPNM3LYSMD30.699801403

For details and further investigation, click here