| Full name: sorting nexin 18 | Alias Symbol: SH3PX2|SH3PXD3B | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 112574 | HGNC ID: HGNC:19245 | Ensembl Gene: ENSG00000178996 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SNX18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX18 | 112574 | 226683_at | -0.0304 | 0.9730 | |
| GSE26886 | SNX18 | 112574 | 226683_at | -0.4299 | 0.2941 | |
| GSE45670 | SNX18 | 112574 | 226683_at | 0.0451 | 0.8816 | |
| GSE53622 | SNX18 | 112574 | 51052 | 0.0196 | 0.8230 | |
| GSE53624 | SNX18 | 112574 | 51052 | 0.1256 | 0.0414 | |
| GSE63941 | SNX18 | 112574 | 226683_at | -2.5436 | 0.0015 | |
| GSE77861 | SNX18 | 112574 | 226683_at | -0.0998 | 0.8661 | |
| GSE97050 | SNX18 | 112574 | A_33_P3250128 | 0.2599 | 0.4582 | |
| SRP007169 | SNX18 | 112574 | RNAseq | 0.0453 | 0.8948 | |
| SRP008496 | SNX18 | 112574 | RNAseq | -0.2622 | 0.2014 | |
| SRP064894 | SNX18 | 112574 | RNAseq | -0.2339 | 0.2187 | |
| SRP133303 | SNX18 | 112574 | RNAseq | -0.3237 | 0.1671 | |
| SRP159526 | SNX18 | 112574 | RNAseq | 0.0267 | 0.9488 | |
| SRP193095 | SNX18 | 112574 | RNAseq | -0.2911 | 0.0085 | |
| SRP219564 | SNX18 | 112574 | RNAseq | -0.6914 | 0.0475 | |
| TCGA | SNX18 | 112574 | RNAseq | -0.2010 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SNX18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX18 | 112574 | 1 | 13 | 16 | |
| GSE20123 | SNX18 | 112574 | 1 | 13 | 16 | |
| GSE43470 | SNX18 | 112574 | 1 | 12 | 30 | |
| GSE46452 | SNX18 | 112574 | 1 | 27 | 31 | |
| GSE47630 | SNX18 | 112574 | 2 | 16 | 22 | |
| GSE54993 | SNX18 | 112574 | 8 | 1 | 61 | |
| GSE54994 | SNX18 | 112574 | 5 | 18 | 30 | |
| GSE60625 | SNX18 | 112574 | 0 | 0 | 11 | |
| GSE74703 | SNX18 | 112574 | 1 | 9 | 26 | |
| GSE74704 | SNX18 | 112574 | 1 | 6 | 13 | |
| TCGA | SNX18 | 112574 | 8 | 45 | 43 |
Total number of gains: 29; Total number of losses: 160; Total Number of normals: 299.
Somatic mutations of SNX18:
Generating mutation plots.
Highly correlated genes for SNX18:
Showing top 20/325 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX18 | SPTBN1 | 0.778574 | 3 | 0 | 3 |
| SNX18 | RNF135 | 0.761217 | 3 | 0 | 3 |
| SNX18 | ASAP2 | 0.758296 | 3 | 0 | 3 |
| SNX18 | ZMAT3 | 0.753257 | 3 | 0 | 3 |
| SNX18 | NBR1 | 0.752901 | 3 | 0 | 3 |
| SNX18 | DIS3L | 0.752326 | 3 | 0 | 3 |
| SNX18 | CUL2 | 0.752244 | 3 | 0 | 3 |
| SNX18 | CTR9 | 0.751982 | 5 | 0 | 5 |
| SNX18 | LCMT2 | 0.750297 | 3 | 0 | 3 |
| SNX18 | TTC23 | 0.749434 | 4 | 0 | 4 |
| SNX18 | FHOD3 | 0.748574 | 3 | 0 | 3 |
| SNX18 | TTC39C | 0.748215 | 3 | 0 | 3 |
| SNX18 | CRBN | 0.748082 | 3 | 0 | 3 |
| SNX18 | RAPGEF2 | 0.747971 | 3 | 0 | 3 |
| SNX18 | FYCO1 | 0.745867 | 3 | 0 | 3 |
| SNX18 | ZDHHC17 | 0.743727 | 3 | 0 | 3 |
| SNX18 | LTBP2 | 0.743687 | 3 | 0 | 3 |
| SNX18 | RALGAPB | 0.742247 | 3 | 0 | 3 |
| SNX18 | SEC63 | 0.742155 | 3 | 0 | 3 |
| SNX18 | AMZ2 | 0.742033 | 3 | 0 | 3 |
For details and further investigation, click here
