| Full name: isopentenyl-diphosphate delta isomerase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10p15.3 | ||
| Entrez ID: 3422 | HGNC ID: HGNC:5387 | Ensembl Gene: ENSG00000067064 | OMIM ID: 604055 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of IDI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IDI1 | 3422 | 208881_x_at | -0.0819 | 0.9088 | |
| GSE20347 | IDI1 | 3422 | 208881_x_at | -0.1060 | 0.5510 | |
| GSE23400 | IDI1 | 3422 | 208881_x_at | -0.2693 | 0.0012 | |
| GSE26886 | IDI1 | 3422 | 208881_x_at | -0.5648 | 0.0346 | |
| GSE29001 | IDI1 | 3422 | 208881_x_at | -0.4520 | 0.2075 | |
| GSE38129 | IDI1 | 3422 | 208881_x_at | 0.0237 | 0.9047 | |
| GSE45670 | IDI1 | 3422 | 204615_x_at | -0.2009 | 0.3011 | |
| GSE53622 | IDI1 | 3422 | 95660 | -0.4954 | 0.0000 | |
| GSE53624 | IDI1 | 3422 | 95660 | -0.3987 | 0.0000 | |
| GSE63941 | IDI1 | 3422 | 208881_x_at | -0.7286 | 0.1877 | |
| GSE77861 | IDI1 | 3422 | 208881_x_at | -0.2620 | 0.2826 | |
| GSE97050 | IDI1 | 3422 | A_24_P103886 | 0.0316 | 0.9695 | |
| SRP007169 | IDI1 | 3422 | RNAseq | -1.4861 | 0.0001 | |
| SRP008496 | IDI1 | 3422 | RNAseq | -1.3713 | 0.0000 | |
| SRP064894 | IDI1 | 3422 | RNAseq | -1.1051 | 0.0000 | |
| SRP133303 | IDI1 | 3422 | RNAseq | -0.3084 | 0.1759 | |
| SRP159526 | IDI1 | 3422 | RNAseq | -0.6121 | 0.1370 | |
| SRP193095 | IDI1 | 3422 | RNAseq | -0.7660 | 0.0000 | |
| SRP219564 | IDI1 | 3422 | RNAseq | -0.6553 | 0.0835 | |
| TCGA | IDI1 | 3422 | RNAseq | -0.0291 | 0.6180 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by IDI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IDI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IDI1 | 3422 | 5 | 10 | 15 | |
| GSE20123 | IDI1 | 3422 | 5 | 10 | 15 | |
| GSE43470 | IDI1 | 3422 | 3 | 8 | 32 | |
| GSE46452 | IDI1 | 3422 | 2 | 14 | 43 | |
| GSE47630 | IDI1 | 3422 | 5 | 15 | 20 | |
| GSE54993 | IDI1 | 3422 | 11 | 0 | 59 | |
| GSE54994 | IDI1 | 3422 | 4 | 10 | 39 | |
| GSE60625 | IDI1 | 3422 | 0 | 0 | 11 | |
| GSE74703 | IDI1 | 3422 | 2 | 5 | 29 | |
| GSE74704 | IDI1 | 3422 | 1 | 9 | 10 | |
| TCGA | IDI1 | 3422 | 17 | 27 | 52 |
Total number of gains: 55; Total number of losses: 108; Total Number of normals: 325.
Somatic mutations of IDI1:
Generating mutation plots.
Highly correlated genes for IDI1:
Showing top 20/349 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IDI1 | PPP1R2 | 0.771663 | 3 | 0 | 3 |
| IDI1 | CHD1 | 0.727792 | 3 | 0 | 3 |
| IDI1 | INTS12 | 0.727491 | 3 | 0 | 3 |
| IDI1 | SERINC1 | 0.726137 | 3 | 0 | 3 |
| IDI1 | TSPAN5 | 0.717744 | 3 | 0 | 3 |
| IDI1 | PRPF38B | 0.715761 | 3 | 0 | 3 |
| IDI1 | OAS1 | 0.707914 | 3 | 0 | 3 |
| IDI1 | ARFGEF2 | 0.705432 | 3 | 0 | 3 |
| IDI1 | BRWD1 | 0.686968 | 3 | 0 | 3 |
| IDI1 | STAMBP | 0.674979 | 3 | 0 | 3 |
| IDI1 | PFDN5 | 0.674202 | 4 | 0 | 3 |
| IDI1 | MOB4 | 0.656213 | 6 | 0 | 5 |
| IDI1 | DDX52 | 0.655326 | 3 | 0 | 3 |
| IDI1 | PSMD7 | 0.651283 | 4 | 0 | 3 |
| IDI1 | CCDC90B | 0.65071 | 3 | 0 | 3 |
| IDI1 | MAP4K5 | 0.646961 | 5 | 0 | 5 |
| IDI1 | SCAMP1 | 0.64632 | 4 | 0 | 4 |
| IDI1 | SEC24B | 0.646281 | 6 | 0 | 4 |
| IDI1 | MSMO1 | 0.644759 | 11 | 0 | 10 |
| IDI1 | EMC2 | 0.636603 | 3 | 0 | 3 |
For details and further investigation, click here
