| Full name: natural killer cell triggering receptor | Alias Symbol: p104 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 4820 | HGNC ID: HGNC:7833 | Ensembl Gene: ENSG00000114857 | OMIM ID: 161565 |
| Drug and gene relationship at DGIdb | |||
Expression of NKTR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NKTR | 4820 | 202379_s_at | -0.2180 | 0.8447 | |
| GSE20347 | NKTR | 4820 | 202379_s_at | -0.2005 | 0.3304 | |
| GSE23400 | NKTR | 4820 | 202379_s_at | -0.1246 | 0.4314 | |
| GSE26886 | NKTR | 4820 | 202380_s_at | -0.6673 | 0.0046 | |
| GSE29001 | NKTR | 4820 | 202379_s_at | -0.1715 | 0.6176 | |
| GSE38129 | NKTR | 4820 | 202379_s_at | -0.3235 | 0.0405 | |
| GSE45670 | NKTR | 4820 | 202379_s_at | -0.3035 | 0.0623 | |
| GSE53622 | NKTR | 4820 | 33734 | 0.0587 | 0.3038 | |
| GSE53624 | NKTR | 4820 | 33734 | 0.0040 | 0.9537 | |
| GSE63941 | NKTR | 4820 | 202379_s_at | -0.9296 | 0.0210 | |
| GSE77861 | NKTR | 4820 | 202379_s_at | 0.2589 | 0.5428 | |
| GSE97050 | NKTR | 4820 | A_24_P926760 | -0.1849 | 0.3566 | |
| SRP007169 | NKTR | 4820 | RNAseq | 0.8667 | 0.0596 | |
| SRP008496 | NKTR | 4820 | RNAseq | 1.0039 | 0.0004 | |
| SRP064894 | NKTR | 4820 | RNAseq | -0.4361 | 0.1466 | |
| SRP133303 | NKTR | 4820 | RNAseq | -0.5160 | 0.0000 | |
| SRP159526 | NKTR | 4820 | RNAseq | -0.8072 | 0.0023 | |
| SRP193095 | NKTR | 4820 | RNAseq | -0.2583 | 0.0346 | |
| SRP219564 | NKTR | 4820 | RNAseq | -0.3285 | 0.4283 | |
| TCGA | NKTR | 4820 | RNAseq | -0.2477 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NKTR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NKTR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NKTR | 4820 | 0 | 19 | 11 | |
| GSE20123 | NKTR | 4820 | 0 | 19 | 11 | |
| GSE43470 | NKTR | 4820 | 0 | 21 | 22 | |
| GSE46452 | NKTR | 4820 | 2 | 17 | 40 | |
| GSE47630 | NKTR | 4820 | 1 | 24 | 15 | |
| GSE54993 | NKTR | 4820 | 7 | 2 | 61 | |
| GSE54994 | NKTR | 4820 | 1 | 34 | 18 | |
| GSE60625 | NKTR | 4820 | 5 | 0 | 6 | |
| GSE74703 | NKTR | 4820 | 0 | 17 | 19 | |
| GSE74704 | NKTR | 4820 | 0 | 13 | 7 | |
| TCGA | NKTR | 4820 | 1 | 71 | 24 |
Total number of gains: 17; Total number of losses: 237; Total Number of normals: 234.
Somatic mutations of NKTR:
Generating mutation plots.
Highly correlated genes for NKTR:
Showing top 20/319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NKTR | NAA25 | 0.832914 | 3 | 0 | 3 |
| NKTR | FAM161B | 0.82908 | 4 | 0 | 4 |
| NKTR | RSF1 | 0.780593 | 3 | 0 | 3 |
| NKTR | CCAR1 | 0.774288 | 4 | 0 | 4 |
| NKTR | EEA1 | 0.762895 | 3 | 0 | 3 |
| NKTR | PGAP1 | 0.762333 | 3 | 0 | 3 |
| NKTR | SERINC1 | 0.760863 | 3 | 0 | 3 |
| NKTR | SCP2 | 0.759609 | 3 | 0 | 3 |
| NKTR | RHBDF1 | 0.758733 | 3 | 0 | 3 |
| NKTR | SNRNP200 | 0.758257 | 3 | 0 | 3 |
| NKTR | PTPN4 | 0.758227 | 3 | 0 | 3 |
| NKTR | CMBL | 0.754799 | 3 | 0 | 3 |
| NKTR | ZSCAN29 | 0.746655 | 3 | 0 | 3 |
| NKTR | AVIL | 0.738326 | 3 | 0 | 3 |
| NKTR | IMPA1 | 0.737758 | 3 | 0 | 3 |
| NKTR | DDX59 | 0.734818 | 4 | 0 | 3 |
| NKTR | ZFP3 | 0.733103 | 3 | 0 | 3 |
| NKTR | ZNF547 | 0.729441 | 3 | 0 | 3 |
| NKTR | METTL14 | 0.723197 | 4 | 0 | 3 |
| NKTR | ZBTB4 | 0.722294 | 3 | 0 | 3 |
For details and further investigation, click here
