| Full name: golgi associated PDZ and coiled-coil motif containing | Alias Symbol: dJ94G16.2|PIST|FIG|GOPC1|CAL | ||
| Type: protein-coding gene | Cytoband: 6q22.1 | ||
| Entrez ID: 57120 | HGNC ID: HGNC:17643 | Ensembl Gene: ENSG00000047932 | OMIM ID: 606845 |
| Drug and gene relationship at DGIdb | |||
Expression of GOPC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GOPC | 57120 | 225022_at | 0.1250 | 0.8634 | |
| GSE26886 | GOPC | 57120 | 225022_at | 0.5887 | 0.0064 | |
| GSE45670 | GOPC | 57120 | 225022_at | 0.1887 | 0.1936 | |
| GSE53622 | GOPC | 57120 | 126750 | 0.3182 | 0.0000 | |
| GSE53624 | GOPC | 57120 | 126750 | 0.3925 | 0.0000 | |
| GSE63941 | GOPC | 57120 | 225022_at | -1.2400 | 0.0297 | |
| GSE77861 | GOPC | 57120 | 225022_at | 0.3982 | 0.0522 | |
| GSE97050 | GOPC | 57120 | A_23_P58877 | 0.0060 | 0.9808 | |
| SRP007169 | GOPC | 57120 | RNAseq | 0.8004 | 0.0365 | |
| SRP008496 | GOPC | 57120 | RNAseq | 1.3550 | 0.0000 | |
| SRP064894 | GOPC | 57120 | RNAseq | 0.4995 | 0.0384 | |
| SRP133303 | GOPC | 57120 | RNAseq | 0.7347 | 0.0000 | |
| SRP159526 | GOPC | 57120 | RNAseq | 0.0007 | 0.9961 | |
| SRP193095 | GOPC | 57120 | RNAseq | 0.2919 | 0.0354 | |
| SRP219564 | GOPC | 57120 | RNAseq | 0.0786 | 0.7167 | |
| TCGA | GOPC | 57120 | RNAseq | 0.0506 | 0.3064 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by GOPC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GOPC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GOPC | 57120 | 1 | 4 | 25 | |
| GSE20123 | GOPC | 57120 | 1 | 3 | 26 | |
| GSE43470 | GOPC | 57120 | 3 | 1 | 39 | |
| GSE46452 | GOPC | 57120 | 2 | 11 | 46 | |
| GSE47630 | GOPC | 57120 | 9 | 4 | 27 | |
| GSE54993 | GOPC | 57120 | 3 | 2 | 65 | |
| GSE54994 | GOPC | 57120 | 8 | 8 | 37 | |
| GSE60625 | GOPC | 57120 | 0 | 1 | 10 | |
| GSE74703 | GOPC | 57120 | 2 | 1 | 33 | |
| GSE74704 | GOPC | 57120 | 0 | 1 | 19 | |
| TCGA | GOPC | 57120 | 9 | 22 | 65 |
Total number of gains: 38; Total number of losses: 58; Total Number of normals: 392.
Somatic mutations of GOPC:
Generating mutation plots.
Highly correlated genes for GOPC:
Showing top 20/760 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GOPC | SFT2D3 | 0.784604 | 3 | 0 | 3 |
| GOPC | IRS2 | 0.764559 | 3 | 0 | 3 |
| GOPC | PGAP1 | 0.763632 | 3 | 0 | 3 |
| GOPC | C6orf141 | 0.760073 | 3 | 0 | 3 |
| GOPC | FOXK2 | 0.753389 | 3 | 0 | 3 |
| GOPC | CYP26B1 | 0.749393 | 3 | 0 | 3 |
| GOPC | SERINC1 | 0.749388 | 3 | 0 | 3 |
| GOPC | STOML1 | 0.743153 | 3 | 0 | 3 |
| GOPC | TRADD | 0.739337 | 3 | 0 | 3 |
| GOPC | ID1 | 0.737393 | 3 | 0 | 3 |
| GOPC | PET117 | 0.730176 | 3 | 0 | 3 |
| GOPC | TBC1D8B | 0.72922 | 4 | 0 | 3 |
| GOPC | MPHOSPH6 | 0.728571 | 3 | 0 | 3 |
| GOPC | TDG | 0.725188 | 3 | 0 | 3 |
| GOPC | GMCL1 | 0.723539 | 4 | 0 | 4 |
| GOPC | ABHD2 | 0.722542 | 3 | 0 | 3 |
| GOPC | STK17A | 0.720019 | 4 | 0 | 3 |
| GOPC | TNFAIP1 | 0.718175 | 3 | 0 | 3 |
| GOPC | LYPLAL1 | 0.717945 | 3 | 0 | 3 |
| GOPC | KREMEN1 | 0.715881 | 3 | 0 | 3 |
For details and further investigation, click here
