| Full name: glucosamine-6-phosphate deaminase 2 | Alias Symbol: SB52 | ||
| Type: protein-coding gene | Cytoband: 4p12 | ||
| Entrez ID: 132789 | HGNC ID: HGNC:21526 | Ensembl Gene: ENSG00000163281 | OMIM ID: 613222 |
| Drug and gene relationship at DGIdb | |||
Expression of GNPDA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GNPDA2 | 132789 | 227022_at | -0.8370 | 0.1186 | |
| GSE26886 | GNPDA2 | 132789 | 227022_at | -0.7101 | 0.0108 | |
| GSE45670 | GNPDA2 | 132789 | 227022_at | -0.7068 | 0.0008 | |
| GSE53622 | GNPDA2 | 132789 | 55151 | -0.4494 | 0.0000 | |
| GSE53624 | GNPDA2 | 132789 | 55151 | -0.2661 | 0.0084 | |
| GSE63941 | GNPDA2 | 132789 | 227022_at | -1.4910 | 0.1236 | |
| GSE77861 | GNPDA2 | 132789 | 227022_at | -0.2268 | 0.4655 | |
| GSE97050 | GNPDA2 | 132789 | A_23_P144578 | -0.6272 | 0.1162 | |
| SRP007169 | GNPDA2 | 132789 | RNAseq | 0.3346 | 0.5324 | |
| SRP008496 | GNPDA2 | 132789 | RNAseq | 0.6025 | 0.0640 | |
| SRP064894 | GNPDA2 | 132789 | RNAseq | -0.0821 | 0.6810 | |
| SRP133303 | GNPDA2 | 132789 | RNAseq | -0.2608 | 0.2164 | |
| SRP159526 | GNPDA2 | 132789 | RNAseq | -0.3612 | 0.0490 | |
| SRP193095 | GNPDA2 | 132789 | RNAseq | -0.3202 | 0.0501 | |
| SRP219564 | GNPDA2 | 132789 | RNAseq | -0.3239 | 0.4625 | |
| TCGA | GNPDA2 | 132789 | RNAseq | -0.2299 | 0.0042 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GNPDA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GNPDA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GNPDA2 | 132789 | 0 | 16 | 14 | |
| GSE20123 | GNPDA2 | 132789 | 0 | 16 | 14 | |
| GSE43470 | GNPDA2 | 132789 | 0 | 14 | 29 | |
| GSE46452 | GNPDA2 | 132789 | 1 | 36 | 22 | |
| GSE47630 | GNPDA2 | 132789 | 1 | 18 | 21 | |
| GSE54993 | GNPDA2 | 132789 | 7 | 0 | 63 | |
| GSE54994 | GNPDA2 | 132789 | 4 | 9 | 40 | |
| GSE60625 | GNPDA2 | 132789 | 0 | 0 | 11 | |
| GSE74703 | GNPDA2 | 132789 | 0 | 12 | 24 | |
| GSE74704 | GNPDA2 | 132789 | 0 | 9 | 11 | |
| TCGA | GNPDA2 | 132789 | 15 | 38 | 43 |
Total number of gains: 28; Total number of losses: 168; Total Number of normals: 292.
Somatic mutations of GNPDA2:
Generating mutation plots.
Highly correlated genes for GNPDA2:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GNPDA2 | CRBN | 0.782613 | 4 | 0 | 4 |
| GNPDA2 | C7 | 0.763533 | 4 | 0 | 4 |
| GNPDA2 | AP1S2 | 0.76229 | 5 | 0 | 5 |
| GNPDA2 | STARD13 | 0.753974 | 4 | 0 | 4 |
| GNPDA2 | STK38L | 0.752045 | 3 | 0 | 3 |
| GNPDA2 | KAT7 | 0.747042 | 3 | 0 | 3 |
| GNPDA2 | TRAK1 | 0.746563 | 3 | 0 | 3 |
| GNPDA2 | SGCB | 0.744242 | 5 | 0 | 5 |
| GNPDA2 | NPY1R | 0.743737 | 3 | 0 | 3 |
| GNPDA2 | ITGA9 | 0.743726 | 5 | 0 | 4 |
| GNPDA2 | MIER1 | 0.742587 | 3 | 0 | 3 |
| GNPDA2 | TXNIP | 0.739661 | 4 | 0 | 4 |
| GNPDA2 | SETMAR | 0.7393 | 3 | 0 | 3 |
| GNPDA2 | NACC2 | 0.738262 | 4 | 0 | 4 |
| GNPDA2 | HPSE2 | 0.737048 | 4 | 0 | 3 |
| GNPDA2 | WDR48 | 0.736226 | 3 | 0 | 3 |
| GNPDA2 | PYGM | 0.734977 | 4 | 0 | 4 |
| GNPDA2 | PJA2 | 0.734169 | 5 | 0 | 5 |
| GNPDA2 | MBD5 | 0.732771 | 4 | 0 | 4 |
| GNPDA2 | C3orf70 | 0.732211 | 5 | 0 | 5 |
For details and further investigation, click here
