| Full name: fibronectin type III domain containing 5 | Alias Symbol: FRCP2 | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 252995 | HGNC ID: HGNC:20240 | Ensembl Gene: ENSG00000160097 | OMIM ID: 611906 |
| Drug and gene relationship at DGIdb | |||
Expression of FNDC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FNDC5 | 252995 | 226096_at | -0.7766 | 0.4319 | |
| GSE26886 | FNDC5 | 252995 | 226097_at | -0.1933 | 0.1572 | |
| GSE45670 | FNDC5 | 252995 | 226097_at | -0.1248 | 0.1247 | |
| GSE53622 | FNDC5 | 252995 | 37430 | -0.6264 | 0.0002 | |
| GSE53624 | FNDC5 | 252995 | 26923 | -0.5121 | 0.0008 | |
| GSE63941 | FNDC5 | 252995 | 226097_at | -0.1846 | 0.3005 | |
| GSE77861 | FNDC5 | 252995 | 226097_at | -0.0571 | 0.7022 | |
| GSE97050 | FNDC5 | 252995 | A_23_P420326 | -1.0119 | 0.1556 | |
| SRP064894 | FNDC5 | 252995 | RNAseq | 0.2827 | 0.5526 | |
| SRP133303 | FNDC5 | 252995 | RNAseq | -1.1214 | 0.0007 | |
| SRP159526 | FNDC5 | 252995 | RNAseq | 0.9403 | 0.1247 | |
| SRP219564 | FNDC5 | 252995 | RNAseq | -0.7240 | 0.5604 | |
| TCGA | FNDC5 | 252995 | RNAseq | -1.7642 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FNDC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FNDC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FNDC5 | 252995 | 2 | 5 | 23 | |
| GSE20123 | FNDC5 | 252995 | 2 | 4 | 24 | |
| GSE43470 | FNDC5 | 252995 | 5 | 6 | 32 | |
| GSE46452 | FNDC5 | 252995 | 5 | 1 | 53 | |
| GSE47630 | FNDC5 | 252995 | 8 | 3 | 29 | |
| GSE54993 | FNDC5 | 252995 | 1 | 1 | 68 | |
| GSE54994 | FNDC5 | 252995 | 11 | 2 | 40 | |
| GSE60625 | FNDC5 | 252995 | 0 | 0 | 11 | |
| GSE74703 | FNDC5 | 252995 | 4 | 3 | 29 | |
| GSE74704 | FNDC5 | 252995 | 1 | 0 | 19 | |
| TCGA | FNDC5 | 252995 | 12 | 18 | 66 |
Total number of gains: 51; Total number of losses: 43; Total Number of normals: 394.
Somatic mutations of FNDC5:
Generating mutation plots.
Highly correlated genes for FNDC5:
Showing top 20/446 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FNDC5 | FBXO30 | 0.841658 | 3 | 0 | 3 |
| FNDC5 | MYOM2 | 0.805091 | 3 | 0 | 3 |
| FNDC5 | CTNNA3 | 0.797892 | 4 | 0 | 4 |
| FNDC5 | RASD2 | 0.79789 | 3 | 0 | 3 |
| FNDC5 | PYGM | 0.78455 | 4 | 0 | 4 |
| FNDC5 | FOXF2 | 0.773787 | 4 | 0 | 4 |
| FNDC5 | SGCD | 0.770904 | 4 | 0 | 4 |
| FNDC5 | TRAK1 | 0.770711 | 3 | 0 | 3 |
| FNDC5 | MYOC | 0.768236 | 4 | 0 | 4 |
| FNDC5 | LMO3 | 0.767239 | 4 | 0 | 4 |
| FNDC5 | EZH1 | 0.764625 | 3 | 0 | 3 |
| FNDC5 | CACNB2 | 0.762625 | 4 | 0 | 4 |
| FNDC5 | ARHGAP6 | 0.760304 | 4 | 0 | 4 |
| FNDC5 | TOR1AIP1 | 0.759009 | 3 | 0 | 3 |
| FNDC5 | SOBP | 0.758198 | 4 | 0 | 4 |
| FNDC5 | WSCD2 | 0.757416 | 4 | 0 | 3 |
| FNDC5 | PDK3 | 0.755425 | 3 | 0 | 3 |
| FNDC5 | PGR | 0.754945 | 5 | 0 | 5 |
| FNDC5 | OCRL | 0.754723 | 4 | 0 | 4 |
| FNDC5 | POPDC2 | 0.754152 | 4 | 0 | 3 |
For details and further investigation, click here
