| Full name: N-acyl phosphatidylethanolamine phospholipase D | Alias Symbol: FMP30|C7orf18|NAPE-PLD | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 222236 | HGNC ID: HGNC:21683 | Ensembl Gene: ENSG00000161048 | OMIM ID: 612334 |
| Drug and gene relationship at DGIdb | |||
Expression of NAPEPLD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAPEPLD | 222236 | 238722_x_at | 1.1993 | 0.0250 | |
| GSE26886 | NAPEPLD | 222236 | 238722_x_at | 0.8489 | 0.0040 | |
| GSE45670 | NAPEPLD | 222236 | 238722_x_at | 0.7685 | 0.0039 | |
| GSE53622 | NAPEPLD | 222236 | 96480 | 0.4209 | 0.0000 | |
| GSE53624 | NAPEPLD | 222236 | 41698 | 0.6845 | 0.0000 | |
| GSE63941 | NAPEPLD | 222236 | 226041_at | -0.3895 | 0.6508 | |
| GSE77861 | NAPEPLD | 222236 | 233539_at | 0.3114 | 0.0872 | |
| GSE97050 | NAPEPLD | 222236 | A_32_P117170 | -0.0491 | 0.8948 | |
| SRP007169 | NAPEPLD | 222236 | RNAseq | 1.7336 | 0.0009 | |
| SRP008496 | NAPEPLD | 222236 | RNAseq | 1.8656 | 0.0000 | |
| SRP064894 | NAPEPLD | 222236 | RNAseq | 0.3898 | 0.0159 | |
| SRP133303 | NAPEPLD | 222236 | RNAseq | 0.7561 | 0.0000 | |
| SRP159526 | NAPEPLD | 222236 | RNAseq | 0.3428 | 0.2727 | |
| SRP193095 | NAPEPLD | 222236 | RNAseq | -0.0082 | 0.9749 | |
| SRP219564 | NAPEPLD | 222236 | RNAseq | 0.7494 | 0.0271 | |
| TCGA | NAPEPLD | 222236 | RNAseq | -0.2422 | 0.0002 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NAPEPLD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAPEPLD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAPEPLD | 222236 | 13 | 0 | 17 | |
| GSE20123 | NAPEPLD | 222236 | 13 | 0 | 17 | |
| GSE43470 | NAPEPLD | 222236 | 6 | 2 | 35 | |
| GSE46452 | NAPEPLD | 222236 | 10 | 1 | 48 | |
| GSE47630 | NAPEPLD | 222236 | 7 | 3 | 30 | |
| GSE54993 | NAPEPLD | 222236 | 1 | 10 | 59 | |
| GSE54994 | NAPEPLD | 222236 | 15 | 3 | 35 | |
| GSE60625 | NAPEPLD | 222236 | 0 | 0 | 11 | |
| GSE74703 | NAPEPLD | 222236 | 6 | 2 | 28 | |
| GSE74704 | NAPEPLD | 222236 | 9 | 0 | 11 | |
| TCGA | NAPEPLD | 222236 | 54 | 6 | 36 |
Total number of gains: 134; Total number of losses: 27; Total Number of normals: 327.
Somatic mutations of NAPEPLD:
Generating mutation plots.
Highly correlated genes for NAPEPLD:
Showing top 20/1141 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAPEPLD | CCDC127 | 0.823333 | 3 | 0 | 3 |
| NAPEPLD | SBNO1 | 0.799194 | 3 | 0 | 3 |
| NAPEPLD | POFUT1 | 0.776864 | 3 | 0 | 3 |
| NAPEPLD | WDR5 | 0.764152 | 4 | 0 | 3 |
| NAPEPLD | MAK16 | 0.762536 | 4 | 0 | 4 |
| NAPEPLD | KCNE3 | 0.76149 | 3 | 0 | 3 |
| NAPEPLD | RRAS2 | 0.760948 | 3 | 0 | 3 |
| NAPEPLD | VANGL2 | 0.760388 | 3 | 0 | 3 |
| NAPEPLD | RAD21 | 0.749158 | 5 | 0 | 5 |
| NAPEPLD | INTS3 | 0.741967 | 3 | 0 | 3 |
| NAPEPLD | RSBN1L | 0.741828 | 3 | 0 | 3 |
| NAPEPLD | GGPS1 | 0.736866 | 4 | 0 | 4 |
| NAPEPLD | SUZ12 | 0.734816 | 3 | 0 | 3 |
| NAPEPLD | LTBR | 0.73473 | 3 | 0 | 3 |
| NAPEPLD | MTERF3 | 0.733899 | 4 | 0 | 4 |
| NAPEPLD | STAT5B | 0.732956 | 3 | 0 | 3 |
| NAPEPLD | KDM5A | 0.732825 | 3 | 0 | 3 |
| NAPEPLD | DHRSX | 0.728191 | 4 | 0 | 4 |
| NAPEPLD | SGCB | 0.726494 | 3 | 0 | 3 |
| NAPEPLD | SLC30A7 | 0.725763 | 3 | 0 | 3 |
For details and further investigation, click here
