| Full name: transmembrane and coiled-coil domain family 2 | Alias Symbol: HUCEP11|FLJ38497 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 9911 | HGNC ID: HGNC:24239 | Ensembl Gene: ENSG00000133069 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMCC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMCC2 | 9911 | 213096_at | 0.4863 | 0.2178 | |
| GSE20347 | TMCC2 | 9911 | 213096_at | 0.2631 | 0.0024 | |
| GSE23400 | TMCC2 | 9911 | 213096_at | 0.2154 | 0.0000 | |
| GSE26886 | TMCC2 | 9911 | 213096_at | 0.4780 | 0.0017 | |
| GSE29001 | TMCC2 | 9911 | 213096_at | 0.7021 | 0.0542 | |
| GSE38129 | TMCC2 | 9911 | 213096_at | 0.2414 | 0.0044 | |
| GSE45670 | TMCC2 | 9911 | 213096_at | 0.4038 | 0.0000 | |
| GSE53622 | TMCC2 | 9911 | 96829 | 0.7052 | 0.0005 | |
| GSE53624 | TMCC2 | 9911 | 96829 | 0.7794 | 0.0000 | |
| GSE63941 | TMCC2 | 9911 | 213096_at | -0.0099 | 0.9746 | |
| GSE77861 | TMCC2 | 9911 | 213096_at | 0.1831 | 0.1567 | |
| GSE97050 | TMCC2 | 9911 | A_32_P133840 | -0.1480 | 0.4780 | |
| SRP007169 | TMCC2 | 9911 | RNAseq | 1.1535 | 0.0883 | |
| SRP064894 | TMCC2 | 9911 | RNAseq | 1.7265 | 0.0000 | |
| SRP133303 | TMCC2 | 9911 | RNAseq | 1.3210 | 0.0026 | |
| SRP159526 | TMCC2 | 9911 | RNAseq | 2.1572 | 0.0000 | |
| SRP219564 | TMCC2 | 9911 | RNAseq | 1.1857 | 0.0151 | |
| TCGA | TMCC2 | 9911 | RNAseq | 0.6777 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by TMCC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMCC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMCC2 | 9911 | 11 | 0 | 19 | |
| GSE20123 | TMCC2 | 9911 | 11 | 0 | 19 | |
| GSE43470 | TMCC2 | 9911 | 6 | 0 | 37 | |
| GSE46452 | TMCC2 | 9911 | 3 | 1 | 55 | |
| GSE47630 | TMCC2 | 9911 | 14 | 0 | 26 | |
| GSE54993 | TMCC2 | 9911 | 0 | 6 | 64 | |
| GSE54994 | TMCC2 | 9911 | 15 | 0 | 38 | |
| GSE60625 | TMCC2 | 9911 | 0 | 0 | 11 | |
| GSE74703 | TMCC2 | 9911 | 6 | 0 | 30 | |
| GSE74704 | TMCC2 | 9911 | 5 | 0 | 15 | |
| TCGA | TMCC2 | 9911 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of TMCC2:
Generating mutation plots.
Highly correlated genes for TMCC2:
Showing top 20/408 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMCC2 | LY6G5C | 0.779943 | 4 | 0 | 4 |
| TMCC2 | SLC19A3 | 0.7722 | 3 | 0 | 3 |
| TMCC2 | CCDC114 | 0.763384 | 3 | 0 | 3 |
| TMCC2 | JAKMIP3 | 0.748494 | 5 | 0 | 4 |
| TMCC2 | ALOX12B | 0.746002 | 3 | 0 | 3 |
| TMCC2 | GJD4 | 0.743965 | 3 | 0 | 3 |
| TMCC2 | KRTAP2-1 | 0.739747 | 3 | 0 | 3 |
| TMCC2 | OR52E2 | 0.720588 | 3 | 0 | 3 |
| TMCC2 | BAHCC1 | 0.711474 | 5 | 0 | 4 |
| TMCC2 | GOLGA7B | 0.710266 | 5 | 0 | 5 |
| TMCC2 | USHBP1 | 0.70412 | 3 | 0 | 3 |
| TMCC2 | HSD17B14 | 0.697603 | 4 | 0 | 4 |
| TMCC2 | BAX | 0.694607 | 4 | 0 | 3 |
| TMCC2 | NTMT1 | 0.692506 | 4 | 0 | 3 |
| TMCC2 | CHMP6 | 0.691392 | 3 | 0 | 3 |
| TMCC2 | MICAL2 | 0.691361 | 3 | 0 | 3 |
| TMCC2 | TRIM43 | 0.689992 | 3 | 0 | 3 |
| TMCC2 | NTNG2 | 0.687156 | 4 | 0 | 3 |
| TMCC2 | RFT1 | 0.685786 | 3 | 0 | 3 |
| TMCC2 | NPBWR1 | 0.682646 | 4 | 0 | 4 |
For details and further investigation, click here
