| Full name: solute carrier family 1 member 7 | Alias Symbol: EAAT5 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 6512 | HGNC ID: HGNC:10945 | Ensembl Gene: ENSG00000162383 | OMIM ID: 604471 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC1A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC1A7 | 6512 | 207355_at | 0.0665 | 0.8436 | |
| GSE20347 | SLC1A7 | 6512 | 207355_at | -0.1667 | 0.0609 | |
| GSE23400 | SLC1A7 | 6512 | 207355_at | -0.1714 | 0.0000 | |
| GSE26886 | SLC1A7 | 6512 | 207355_at | -0.0624 | 0.6571 | |
| GSE29001 | SLC1A7 | 6512 | 207355_at | -0.2027 | 0.0800 | |
| GSE38129 | SLC1A7 | 6512 | 207355_at | -0.3522 | 0.0036 | |
| GSE45670 | SLC1A7 | 6512 | 207355_at | 0.1319 | 0.1226 | |
| GSE53622 | SLC1A7 | 6512 | 45120 | -0.0589 | 0.3503 | |
| GSE53624 | SLC1A7 | 6512 | 45120 | -0.0120 | 0.8702 | |
| GSE63941 | SLC1A7 | 6512 | 207355_at | 0.3690 | 0.0753 | |
| GSE77861 | SLC1A7 | 6512 | 207355_at | -0.1398 | 0.2596 | |
| GSE97050 | SLC1A7 | 6512 | A_23_P325562 | -0.1914 | 0.6488 | |
| SRP133303 | SLC1A7 | 6512 | RNAseq | -1.1786 | 0.0002 | |
| SRP159526 | SLC1A7 | 6512 | RNAseq | -1.5436 | 0.0168 | |
| SRP219564 | SLC1A7 | 6512 | RNAseq | -1.0499 | 0.3411 | |
| TCGA | SLC1A7 | 6512 | RNAseq | -2.0072 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SLC1A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC1A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC1A7 | 6512 | 3 | 4 | 23 | |
| GSE20123 | SLC1A7 | 6512 | 3 | 3 | 24 | |
| GSE43470 | SLC1A7 | 6512 | 6 | 2 | 35 | |
| GSE46452 | SLC1A7 | 6512 | 2 | 1 | 56 | |
| GSE47630 | SLC1A7 | 6512 | 8 | 4 | 28 | |
| GSE54993 | SLC1A7 | 6512 | 0 | 1 | 69 | |
| GSE54994 | SLC1A7 | 6512 | 11 | 2 | 40 | |
| GSE60625 | SLC1A7 | 6512 | 0 | 0 | 11 | |
| GSE74703 | SLC1A7 | 6512 | 4 | 1 | 31 | |
| GSE74704 | SLC1A7 | 6512 | 2 | 0 | 18 | |
| TCGA | SLC1A7 | 6512 | 10 | 18 | 68 |
Total number of gains: 49; Total number of losses: 36; Total Number of normals: 403.
Somatic mutations of SLC1A7:
Generating mutation plots.
Highly correlated genes for SLC1A7:
Showing top 20/939 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC1A7 | TCTE3 | 0.729347 | 3 | 0 | 3 |
| SLC1A7 | FAM151A | 0.706213 | 3 | 0 | 3 |
| SLC1A7 | FAM71A | 0.696015 | 3 | 0 | 3 |
| SLC1A7 | THPO | 0.689537 | 6 | 0 | 5 |
| SLC1A7 | MASP2 | 0.687379 | 6 | 0 | 5 |
| SLC1A7 | ANHX | 0.687258 | 3 | 0 | 3 |
| SLC1A7 | ENGASE | 0.685849 | 3 | 0 | 3 |
| SLC1A7 | GRIN1 | 0.684773 | 5 | 0 | 5 |
| SLC1A7 | CYP3A43 | 0.675049 | 5 | 0 | 5 |
| SLC1A7 | DUX1 | 0.673901 | 5 | 0 | 5 |
| SLC1A7 | GJD4 | 0.673897 | 4 | 0 | 4 |
| SLC1A7 | PRRG3 | 0.673149 | 3 | 0 | 3 |
| SLC1A7 | TMEM95 | 0.670176 | 3 | 0 | 3 |
| SLC1A7 | RASL10B | 0.670029 | 3 | 0 | 3 |
| SLC1A7 | FMNL1 | 0.66969 | 3 | 0 | 3 |
| SLC1A7 | SLC10A1 | 0.668921 | 6 | 0 | 5 |
| SLC1A7 | MMP25 | 0.666339 | 6 | 0 | 5 |
| SLC1A7 | SKAP1 | 0.66465 | 3 | 0 | 3 |
| SLC1A7 | TULP2 | 0.664598 | 6 | 0 | 5 |
| SLC1A7 | GNRH2 | 0.664297 | 7 | 0 | 5 |
For details and further investigation, click here
