| Full name: gonadotropin releasing hormone 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 2797 | HGNC ID: HGNC:4420 | Ensembl Gene: ENSG00000125787 | OMIM ID: 602352 |
| Drug and gene relationship at DGIdb | |||
GNRH2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04912 | GnRH signaling pathway |
Expression of GNRH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GNRH2 | 2797 | 208519_x_at | -0.1391 | 0.5465 | |
| GSE20347 | GNRH2 | 2797 | 208519_x_at | -0.1744 | 0.0747 | |
| GSE23400 | GNRH2 | 2797 | 208519_x_at | -0.2245 | 0.0000 | |
| GSE26886 | GNRH2 | 2797 | 208519_x_at | 0.2193 | 0.0632 | |
| GSE29001 | GNRH2 | 2797 | 208519_x_at | -0.1266 | 0.4339 | |
| GSE38129 | GNRH2 | 2797 | 208519_x_at | -0.2526 | 0.0058 | |
| GSE45670 | GNRH2 | 2797 | 208519_x_at | 0.1230 | 0.2095 | |
| GSE53622 | GNRH2 | 2797 | 23883 | 0.0799 | 0.3087 | |
| GSE53624 | GNRH2 | 2797 | 23883 | 0.0466 | 0.5852 | |
| GSE63941 | GNRH2 | 2797 | 208519_x_at | 0.0701 | 0.6551 | |
| GSE77861 | GNRH2 | 2797 | 208519_x_at | 0.0857 | 0.6259 | |
| GSE97050 | GNRH2 | 2797 | A_24_P323072 | 0.0599 | 0.8355 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GNRH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GNRH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GNRH2 | 2797 | 12 | 3 | 15 | |
| GSE20123 | GNRH2 | 2797 | 13 | 3 | 14 | |
| GSE43470 | GNRH2 | 2797 | 10 | 1 | 32 | |
| GSE46452 | GNRH2 | 2797 | 26 | 1 | 32 | |
| GSE47630 | GNRH2 | 2797 | 18 | 4 | 18 | |
| GSE54993 | GNRH2 | 2797 | 2 | 14 | 54 | |
| GSE54994 | GNRH2 | 2797 | 24 | 2 | 27 | |
| GSE60625 | GNRH2 | 2797 | 0 | 0 | 11 | |
| GSE74703 | GNRH2 | 2797 | 9 | 1 | 26 | |
| GSE74704 | GNRH2 | 2797 | 8 | 1 | 11 | |
| TCGA | GNRH2 | 2797 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of GNRH2:
Generating mutation plots.
Highly correlated genes for GNRH2:
Showing top 20/1036 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GNRH2 | C9orf153 | 0.797943 | 3 | 0 | 3 |
| GNRH2 | STRC | 0.771152 | 3 | 0 | 3 |
| GNRH2 | YY2 | 0.750685 | 3 | 0 | 3 |
| GNRH2 | TSPAN11 | 0.730402 | 3 | 0 | 3 |
| GNRH2 | PLA2G2C | 0.729324 | 3 | 0 | 3 |
| GNRH2 | MRGPRG | 0.726415 | 3 | 0 | 3 |
| GNRH2 | PRSS38 | 0.716179 | 3 | 0 | 3 |
| GNRH2 | ZNF527 | 0.713872 | 4 | 0 | 3 |
| GNRH2 | SLC6A5 | 0.711477 | 3 | 0 | 3 |
| GNRH2 | LBX2 | 0.707934 | 3 | 0 | 3 |
| GNRH2 | KRT74 | 0.70693 | 5 | 0 | 4 |
| GNRH2 | DEFB128 | 0.703127 | 3 | 0 | 3 |
| GNRH2 | DPEP1 | 0.702842 | 5 | 0 | 5 |
| GNRH2 | LINC01260 | 0.702815 | 4 | 0 | 4 |
| GNRH2 | RAPGEF3 | 0.701389 | 7 | 0 | 7 |
| GNRH2 | CYP2D6 | 0.69945 | 7 | 0 | 7 |
| GNRH2 | GFI1B | 0.697974 | 3 | 0 | 3 |
| GNRH2 | PNPLA7 | 0.69779 | 3 | 0 | 3 |
| GNRH2 | IFNL2 | 0.696997 | 3 | 0 | 3 |
| GNRH2 | OR2T27 | 0.696103 | 3 | 0 | 3 |
For details and further investigation, click here
