| Full name: formin like 1 | Alias Symbol: C17orf1 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 752 | HGNC ID: HGNC:1212 | Ensembl Gene: ENSG00000184922 | OMIM ID: 604656 |
| Drug and gene relationship at DGIdb | |||
Expression of FMNL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMNL1 | 752 | 204789_at | 0.2375 | 0.6380 | |
| GSE20347 | FMNL1 | 752 | 204789_at | 0.1355 | 0.0943 | |
| GSE23400 | FMNL1 | 752 | 204789_at | 0.0478 | 0.1579 | |
| GSE26886 | FMNL1 | 752 | 204789_at | 0.2419 | 0.0856 | |
| GSE29001 | FMNL1 | 752 | 204789_at | -0.0391 | 0.7999 | |
| GSE38129 | FMNL1 | 752 | 204789_at | 0.0319 | 0.7341 | |
| GSE45670 | FMNL1 | 752 | 204789_at | 0.0395 | 0.6293 | |
| GSE53622 | FMNL1 | 752 | 72254 | 0.3067 | 0.0038 | |
| GSE53624 | FMNL1 | 752 | 72254 | 0.2164 | 0.0396 | |
| GSE63941 | FMNL1 | 752 | 204789_at | -0.1246 | 0.5027 | |
| GSE77861 | FMNL1 | 752 | 204789_at | 0.1012 | 0.4048 | |
| GSE97050 | FMNL1 | 752 | A_33_P3382303 | 0.4629 | 0.2084 | |
| SRP007169 | FMNL1 | 752 | RNAseq | 1.3967 | 0.0701 | |
| SRP064894 | FMNL1 | 752 | RNAseq | 0.3269 | 0.1676 | |
| SRP133303 | FMNL1 | 752 | RNAseq | -0.0677 | 0.6808 | |
| SRP159526 | FMNL1 | 752 | RNAseq | -0.1509 | 0.7370 | |
| SRP193095 | FMNL1 | 752 | RNAseq | 0.7626 | 0.0005 | |
| SRP219564 | FMNL1 | 752 | RNAseq | 1.0028 | 0.0166 | |
| TCGA | FMNL1 | 752 | RNAseq | 0.0937 | 0.3300 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FMNL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMNL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMNL1 | 752 | 6 | 2 | 22 | |
| GSE20123 | FMNL1 | 752 | 6 | 2 | 22 | |
| GSE43470 | FMNL1 | 752 | 3 | 2 | 38 | |
| GSE46452 | FMNL1 | 752 | 32 | 0 | 27 | |
| GSE47630 | FMNL1 | 752 | 9 | 0 | 31 | |
| GSE54993 | FMNL1 | 752 | 3 | 4 | 63 | |
| GSE54994 | FMNL1 | 752 | 9 | 5 | 39 | |
| GSE60625 | FMNL1 | 752 | 4 | 0 | 7 | |
| GSE74703 | FMNL1 | 752 | 2 | 1 | 33 | |
| GSE74704 | FMNL1 | 752 | 4 | 1 | 15 | |
| TCGA | FMNL1 | 752 | 26 | 7 | 63 |
Total number of gains: 104; Total number of losses: 24; Total Number of normals: 360.
Somatic mutations of FMNL1:
Generating mutation plots.
Highly correlated genes for FMNL1:
Showing top 20/447 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMNL1 | TBC1D10C | 0.817543 | 3 | 0 | 3 |
| FMNL1 | MEPE | 0.78722 | 3 | 0 | 3 |
| FMNL1 | IL9R | 0.782603 | 3 | 0 | 3 |
| FMNL1 | METTL7B | 0.774628 | 3 | 0 | 3 |
| FMNL1 | HECW1 | 0.765708 | 3 | 0 | 3 |
| FMNL1 | ABCA4 | 0.753537 | 3 | 0 | 3 |
| FMNL1 | TSPO2 | 0.752328 | 3 | 0 | 3 |
| FMNL1 | CEBPE | 0.751921 | 3 | 0 | 3 |
| FMNL1 | GABRD | 0.751459 | 4 | 0 | 4 |
| FMNL1 | SH2D5 | 0.750308 | 3 | 0 | 3 |
| FMNL1 | RAI1 | 0.743002 | 3 | 0 | 3 |
| FMNL1 | TNFRSF1B | 0.740079 | 5 | 0 | 5 |
| FMNL1 | RCOR2 | 0.737914 | 3 | 0 | 3 |
| FMNL1 | JAK3 | 0.736649 | 5 | 0 | 4 |
| FMNL1 | SMARCB1 | 0.735302 | 3 | 0 | 3 |
| FMNL1 | PTGIR | 0.725837 | 4 | 0 | 4 |
| FMNL1 | PTPRCAP | 0.725244 | 5 | 0 | 5 |
| FMNL1 | STK11 | 0.724709 | 3 | 0 | 3 |
| FMNL1 | APOH | 0.724563 | 3 | 0 | 3 |
| FMNL1 | LAIR1 | 0.719542 | 4 | 0 | 3 |
For details and further investigation, click here
