| Full name: solute carrier family 4 member 2 | Alias Symbol: HKB3|BND3L|NBND3 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 6522 | HGNC ID: HGNC:11028 | Ensembl Gene: ENSG00000164889 | OMIM ID: 109280 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC4A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC4A2 | 6522 | 202111_at | 0.4034 | 0.2400 | |
| GSE20347 | SLC4A2 | 6522 | 202111_at | 0.4964 | 0.0001 | |
| GSE23400 | SLC4A2 | 6522 | 202111_at | 0.2621 | 0.0001 | |
| GSE26886 | SLC4A2 | 6522 | 202111_at | -0.1130 | 0.6906 | |
| GSE29001 | SLC4A2 | 6522 | 202111_at | 0.4277 | 0.2488 | |
| GSE38129 | SLC4A2 | 6522 | 202111_at | 0.3782 | 0.0009 | |
| GSE45670 | SLC4A2 | 6522 | 202111_at | 0.1240 | 0.2235 | |
| GSE53622 | SLC4A2 | 6522 | 10944 | 0.4471 | 0.0000 | |
| GSE53624 | SLC4A2 | 6522 | 53719 | 0.3374 | 0.0000 | |
| GSE63941 | SLC4A2 | 6522 | 202111_at | 0.6196 | 0.0921 | |
| GSE77861 | SLC4A2 | 6522 | 202111_at | 0.4865 | 0.0142 | |
| GSE97050 | SLC4A2 | 6522 | A_23_P253389 | 0.3559 | 0.2630 | |
| SRP007169 | SLC4A2 | 6522 | RNAseq | 0.5726 | 0.2397 | |
| SRP008496 | SLC4A2 | 6522 | RNAseq | 0.6181 | 0.0169 | |
| SRP064894 | SLC4A2 | 6522 | RNAseq | 1.0154 | 0.0000 | |
| SRP133303 | SLC4A2 | 6522 | RNAseq | 0.3365 | 0.0174 | |
| SRP159526 | SLC4A2 | 6522 | RNAseq | 0.3028 | 0.0872 | |
| SRP193095 | SLC4A2 | 6522 | RNAseq | 0.5835 | 0.0020 | |
| SRP219564 | SLC4A2 | 6522 | RNAseq | 0.0636 | 0.8430 | |
| TCGA | SLC4A2 | 6522 | RNAseq | -0.4660 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC4A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC4A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC4A2 | 6522 | 2 | 4 | 24 | |
| GSE20123 | SLC4A2 | 6522 | 2 | 4 | 24 | |
| GSE43470 | SLC4A2 | 6522 | 2 | 5 | 36 | |
| GSE46452 | SLC4A2 | 6522 | 7 | 2 | 50 | |
| GSE47630 | SLC4A2 | 6522 | 5 | 9 | 26 | |
| GSE54993 | SLC4A2 | 6522 | 3 | 3 | 64 | |
| GSE54994 | SLC4A2 | 6522 | 5 | 8 | 40 | |
| GSE60625 | SLC4A2 | 6522 | 0 | 0 | 11 | |
| GSE74703 | SLC4A2 | 6522 | 2 | 4 | 30 | |
| GSE74704 | SLC4A2 | 6522 | 1 | 4 | 15 | |
| TCGA | SLC4A2 | 6522 | 26 | 25 | 45 |
Total number of gains: 55; Total number of losses: 68; Total Number of normals: 365.
Somatic mutations of SLC4A2:
Generating mutation plots.
Highly correlated genes for SLC4A2:
Showing top 20/721 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC4A2 | KLF13 | 0.77233 | 3 | 0 | 3 |
| SLC4A2 | PIGX | 0.750629 | 3 | 0 | 3 |
| SLC4A2 | TMSB15B | 0.742371 | 3 | 0 | 3 |
| SLC4A2 | PHLDB2 | 0.735043 | 3 | 0 | 3 |
| SLC4A2 | NGF | 0.730667 | 3 | 0 | 3 |
| SLC4A2 | PTGFRN | 0.721605 | 3 | 0 | 3 |
| SLC4A2 | CXXC1 | 0.721482 | 4 | 0 | 3 |
| SLC4A2 | ALS2 | 0.720271 | 3 | 0 | 3 |
| SLC4A2 | MAPK11 | 0.714693 | 3 | 0 | 3 |
| SLC4A2 | C1orf174 | 0.709504 | 3 | 0 | 3 |
| SLC4A2 | PRTFDC1 | 0.709297 | 3 | 0 | 3 |
| SLC4A2 | RNF26 | 0.70929 | 3 | 0 | 3 |
| SLC4A2 | RILPL1 | 0.708331 | 3 | 0 | 3 |
| SLC4A2 | ACACA | 0.699943 | 3 | 0 | 3 |
| SLC4A2 | TMEM209 | 0.698756 | 3 | 0 | 3 |
| SLC4A2 | TINAGL1 | 0.698666 | 3 | 0 | 3 |
| SLC4A2 | SLC41A1 | 0.698425 | 4 | 0 | 4 |
| SLC4A2 | HAS3 | 0.693114 | 4 | 0 | 3 |
| SLC4A2 | FLYWCH1 | 0.69292 | 3 | 0 | 3 |
| SLC4A2 | ADAM23 | 0.691362 | 3 | 0 | 3 |
For details and further investigation, click here
