| Full name: phosphoribosyl transferase domain containing 1 | Alias Symbol: HHGP | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 56952 | HGNC ID: HGNC:23333 | Ensembl Gene: ENSG00000099256 | OMIM ID: 610751 |
| Drug and gene relationship at DGIdb | |||
Expression of PRTFDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRTFDC1 | 56952 | 222803_at | 0.4997 | 0.6127 | |
| GSE26886 | PRTFDC1 | 56952 | 222803_at | 2.9893 | 0.0000 | |
| GSE45670 | PRTFDC1 | 56952 | 222803_at | 0.2025 | 0.7461 | |
| GSE53622 | PRTFDC1 | 56952 | 51249 | 1.3462 | 0.0000 | |
| GSE53624 | PRTFDC1 | 56952 | 51249 | 1.6330 | 0.0000 | |
| GSE63941 | PRTFDC1 | 56952 | 222803_at | -1.3817 | 0.5863 | |
| GSE77861 | PRTFDC1 | 56952 | 222803_at | 1.6332 | 0.0067 | |
| GSE97050 | PRTFDC1 | 56952 | A_33_P3380529 | 0.4604 | 0.2939 | |
| SRP007169 | PRTFDC1 | 56952 | RNAseq | 3.4047 | 0.0000 | |
| SRP008496 | PRTFDC1 | 56952 | RNAseq | 3.4246 | 0.0000 | |
| SRP064894 | PRTFDC1 | 56952 | RNAseq | 0.6604 | 0.0027 | |
| SRP133303 | PRTFDC1 | 56952 | RNAseq | 1.0767 | 0.0003 | |
| SRP159526 | PRTFDC1 | 56952 | RNAseq | 1.4518 | 0.0057 | |
| SRP193095 | PRTFDC1 | 56952 | RNAseq | 0.9812 | 0.0094 | |
| SRP219564 | PRTFDC1 | 56952 | RNAseq | -0.0619 | 0.9327 | |
| TCGA | PRTFDC1 | 56952 | RNAseq | -0.1338 | 0.4926 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by PRTFDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRTFDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRTFDC1 | 56952 | 5 | 7 | 18 | |
| GSE20123 | PRTFDC1 | 56952 | 5 | 6 | 19 | |
| GSE43470 | PRTFDC1 | 56952 | 4 | 4 | 35 | |
| GSE46452 | PRTFDC1 | 56952 | 1 | 14 | 44 | |
| GSE47630 | PRTFDC1 | 56952 | 5 | 15 | 20 | |
| GSE54993 | PRTFDC1 | 56952 | 9 | 0 | 61 | |
| GSE54994 | PRTFDC1 | 56952 | 3 | 9 | 41 | |
| GSE60625 | PRTFDC1 | 56952 | 0 | 0 | 11 | |
| GSE74703 | PRTFDC1 | 56952 | 3 | 2 | 31 | |
| GSE74704 | PRTFDC1 | 56952 | 0 | 5 | 15 | |
| TCGA | PRTFDC1 | 56952 | 18 | 24 | 54 |
Total number of gains: 53; Total number of losses: 86; Total Number of normals: 349.
Somatic mutations of PRTFDC1:
Generating mutation plots.
Highly correlated genes for PRTFDC1:
Showing top 20/1668 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRTFDC1 | RAB34 | 0.811149 | 3 | 0 | 3 |
| PRTFDC1 | SLC38A10 | 0.799055 | 3 | 0 | 3 |
| PRTFDC1 | FUBP1 | 0.796728 | 3 | 0 | 3 |
| PRTFDC1 | ZNF827 | 0.784865 | 6 | 0 | 6 |
| PRTFDC1 | NF1 | 0.77558 | 3 | 0 | 3 |
| PRTFDC1 | TMTC1 | 0.773343 | 3 | 0 | 3 |
| PRTFDC1 | PSMB4 | 0.772445 | 4 | 0 | 4 |
| PRTFDC1 | RAI14 | 0.771738 | 5 | 0 | 5 |
| PRTFDC1 | CPT1A | 0.767497 | 3 | 0 | 3 |
| PRTFDC1 | RAD23A | 0.763828 | 3 | 0 | 3 |
| PRTFDC1 | RAD54L | 0.76351 | 3 | 0 | 3 |
| PRTFDC1 | RRAS2 | 0.760193 | 3 | 0 | 3 |
| PRTFDC1 | PTGS2 | 0.759883 | 3 | 0 | 3 |
| PRTFDC1 | PYCR2 | 0.759335 | 3 | 0 | 3 |
| PRTFDC1 | EPPK1 | 0.754767 | 4 | 0 | 4 |
| PRTFDC1 | CALU | 0.750552 | 6 | 0 | 6 |
| PRTFDC1 | FOXC2 | 0.750086 | 3 | 0 | 3 |
| PRTFDC1 | PXDN | 0.749343 | 6 | 0 | 6 |
| PRTFDC1 | SNAP47 | 0.74562 | 3 | 0 | 3 |
| PRTFDC1 | PSMD4 | 0.741815 | 4 | 0 | 4 |
For details and further investigation, click here
