| Full name: hyaluronan synthase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 3038 | HGNC ID: HGNC:4820 | Ensembl Gene: ENSG00000103044 | OMIM ID: 602428 |
| Drug and gene relationship at DGIdb | |||
Expression of HAS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAS3 | 3038 | 223541_at | 2.0566 | 0.1787 | |
| GSE26886 | HAS3 | 3038 | 223541_at | -0.3435 | 0.6030 | |
| GSE45670 | HAS3 | 3038 | 223541_at | 2.3469 | 0.0000 | |
| GSE53622 | HAS3 | 3038 | 118721 | 0.6152 | 0.0000 | |
| GSE53624 | HAS3 | 3038 | 118721 | 0.0415 | 0.7037 | |
| GSE63941 | HAS3 | 3038 | 223541_at | 2.9788 | 0.0377 | |
| GSE77861 | HAS3 | 3038 | 223541_at | 2.7968 | 0.0003 | |
| GSE97050 | HAS3 | 3038 | A_33_P3402454 | 0.4449 | 0.1365 | |
| SRP007169 | HAS3 | 3038 | RNAseq | 3.3801 | 0.0000 | |
| SRP008496 | HAS3 | 3038 | RNAseq | 1.9869 | 0.0062 | |
| SRP064894 | HAS3 | 3038 | RNAseq | 1.5592 | 0.0106 | |
| SRP133303 | HAS3 | 3038 | RNAseq | 1.9019 | 0.0000 | |
| SRP159526 | HAS3 | 3038 | RNAseq | 1.2880 | 0.0907 | |
| SRP193095 | HAS3 | 3038 | RNAseq | 1.6518 | 0.0000 | |
| SRP219564 | HAS3 | 3038 | RNAseq | 0.0107 | 0.9914 | |
| TCGA | HAS3 | 3038 | RNAseq | 0.8432 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by HAS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAS3 | 3038 | 8 | 1 | 21 | |
| GSE20123 | HAS3 | 3038 | 8 | 1 | 21 | |
| GSE43470 | HAS3 | 3038 | 2 | 8 | 33 | |
| GSE46452 | HAS3 | 3038 | 38 | 1 | 20 | |
| GSE47630 | HAS3 | 3038 | 11 | 8 | 21 | |
| GSE54993 | HAS3 | 3038 | 2 | 4 | 64 | |
| GSE54994 | HAS3 | 3038 | 8 | 10 | 35 | |
| GSE60625 | HAS3 | 3038 | 4 | 0 | 7 | |
| GSE74703 | HAS3 | 3038 | 2 | 5 | 29 | |
| GSE74704 | HAS3 | 3038 | 4 | 0 | 16 | |
| TCGA | HAS3 | 3038 | 29 | 14 | 53 |
Total number of gains: 116; Total number of losses: 52; Total Number of normals: 320.
Somatic mutations of HAS3:
Generating mutation plots.
Highly correlated genes for HAS3:
Showing top 20/1020 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAS3 | NUAK1 | 0.83341 | 3 | 0 | 3 |
| HAS3 | IKBIP | 0.815832 | 3 | 0 | 3 |
| HAS3 | AMMECR1L | 0.80506 | 3 | 0 | 3 |
| HAS3 | ITGAV | 0.800788 | 3 | 0 | 3 |
| HAS3 | KHSRP | 0.789925 | 3 | 0 | 3 |
| HAS3 | MLLT11 | 0.787549 | 3 | 0 | 3 |
| HAS3 | PSMB1 | 0.785156 | 3 | 0 | 3 |
| HAS3 | SPRED1 | 0.782748 | 3 | 0 | 3 |
| HAS3 | TSFM | 0.778149 | 3 | 0 | 3 |
| HAS3 | XPR1 | 0.775016 | 5 | 0 | 5 |
| HAS3 | LRRC59 | 0.774878 | 4 | 0 | 4 |
| HAS3 | SLC36A1 | 0.773846 | 4 | 0 | 4 |
| HAS3 | PAPOLG | 0.770797 | 3 | 0 | 3 |
| HAS3 | TMEM97 | 0.764243 | 3 | 0 | 3 |
| HAS3 | CENPL | 0.762886 | 3 | 0 | 3 |
| HAS3 | KCNS3 | 0.76088 | 4 | 0 | 4 |
| HAS3 | TMEM132A | 0.759728 | 4 | 0 | 4 |
| HAS3 | PDIA4 | 0.756942 | 4 | 0 | 4 |
| HAS3 | U2AF2 | 0.756737 | 3 | 0 | 3 |
| HAS3 | RAD23A | 0.756618 | 4 | 0 | 4 |
For details and further investigation, click here
