| Full name: prostaglandin F2 receptor inhibitor | Alias Symbol: FPRP|EWI-F|CD9P-1|FLJ11001|KIAA1436|SMAP-6|CD315 | ||
| Type: protein-coding gene | Cytoband: 1p13.1 | ||
| Entrez ID: 5738 | HGNC ID: HGNC:9601 | Ensembl Gene: ENSG00000134247 | OMIM ID: 601204 |
| Drug and gene relationship at DGIdb | |||
Expression of PTGFRN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTGFRN | 5738 | 224937_at | 0.3353 | 0.5400 | |
| GSE26886 | PTGFRN | 5738 | 224937_at | 0.8781 | 0.0101 | |
| GSE45670 | PTGFRN | 5738 | 224937_at | 0.7337 | 0.0007 | |
| GSE53622 | PTGFRN | 5738 | 23504 | 0.9173 | 0.0000 | |
| GSE53624 | PTGFRN | 5738 | 23504 | 1.1442 | 0.0000 | |
| GSE63941 | PTGFRN | 5738 | 224937_at | 0.3013 | 0.6667 | |
| GSE77861 | PTGFRN | 5738 | 224937_at | 0.8510 | 0.0396 | |
| GSE97050 | PTGFRN | 5738 | A_33_P3307197 | 0.0913 | 0.6558 | |
| SRP007169 | PTGFRN | 5738 | RNAseq | 2.3884 | 0.0000 | |
| SRP008496 | PTGFRN | 5738 | RNAseq | 2.3184 | 0.0000 | |
| SRP064894 | PTGFRN | 5738 | RNAseq | 1.7237 | 0.0000 | |
| SRP133303 | PTGFRN | 5738 | RNAseq | 1.6416 | 0.0000 | |
| SRP159526 | PTGFRN | 5738 | RNAseq | 0.5048 | 0.0167 | |
| SRP193095 | PTGFRN | 5738 | RNAseq | 1.1793 | 0.0000 | |
| SRP219564 | PTGFRN | 5738 | RNAseq | 1.1108 | 0.1682 | |
| TCGA | PTGFRN | 5738 | RNAseq | 0.3000 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by PTGFRN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTGFRN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTGFRN | 5738 | 0 | 9 | 21 | |
| GSE20123 | PTGFRN | 5738 | 0 | 9 | 21 | |
| GSE43470 | PTGFRN | 5738 | 0 | 5 | 38 | |
| GSE46452 | PTGFRN | 5738 | 2 | 1 | 56 | |
| GSE47630 | PTGFRN | 5738 | 9 | 5 | 26 | |
| GSE54993 | PTGFRN | 5738 | 0 | 1 | 69 | |
| GSE54994 | PTGFRN | 5738 | 10 | 2 | 41 | |
| GSE60625 | PTGFRN | 5738 | 0 | 0 | 11 | |
| GSE74703 | PTGFRN | 5738 | 0 | 4 | 32 | |
| GSE74704 | PTGFRN | 5738 | 0 | 5 | 15 | |
| TCGA | PTGFRN | 5738 | 15 | 28 | 53 |
Total number of gains: 36; Total number of losses: 69; Total Number of normals: 383.
Somatic mutations of PTGFRN:
Generating mutation plots.
Highly correlated genes for PTGFRN:
Showing top 20/1260 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTGFRN | CERS2 | 0.857116 | 3 | 0 | 3 |
| PTGFRN | CLASP1 | 0.803847 | 3 | 0 | 3 |
| PTGFRN | TMTC1 | 0.800836 | 3 | 0 | 3 |
| PTGFRN | USP14 | 0.79709 | 3 | 0 | 3 |
| PTGFRN | MPV17 | 0.781842 | 3 | 0 | 3 |
| PTGFRN | GNS | 0.776108 | 3 | 0 | 3 |
| PTGFRN | PIP4K2B | 0.770553 | 3 | 0 | 3 |
| PTGFRN | CRISPLD2 | 0.769558 | 3 | 0 | 3 |
| PTGFRN | INTS1 | 0.767168 | 3 | 0 | 3 |
| PTGFRN | SNTB2 | 0.763693 | 3 | 0 | 3 |
| PTGFRN | FBN1 | 0.761713 | 3 | 0 | 3 |
| PTGFRN | BORA | 0.761174 | 3 | 0 | 3 |
| PTGFRN | C12orf57 | 0.760302 | 3 | 0 | 3 |
| PTGFRN | GNG10 | 0.758088 | 3 | 0 | 3 |
| PTGFRN | CRTC2 | 0.756611 | 3 | 0 | 3 |
| PTGFRN | NXN | 0.756047 | 3 | 0 | 3 |
| PTGFRN | FILIP1L | 0.755352 | 3 | 0 | 3 |
| PTGFRN | TRIB1 | 0.754411 | 3 | 0 | 3 |
| PTGFRN | RNMT | 0.751023 | 3 | 0 | 3 |
| PTGFRN | CCDC85B | 0.749447 | 4 | 0 | 4 |
For details and further investigation, click here
