PIGX

 

Full name: phosphatidylinositol glycan anchor biosynthesis class X Alias Symbol: FLJ20522
Type: protein-coding gene Cytoband: 3q29
Entrez ID: 54965 HGNC ID: HGNC:26046 Ensembl Gene: ENSG00000163964 OMIM ID: 610276
Drug and gene relationship at DGIdb

 

Expression of PIGX:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PIGX 54965 1563111_a_at 1.1121 0.1551
GSE26886 PIGX 54965 1552291_at 1.3680 0.0001
GSE45670 PIGX 54965 1563111_a_at 1.2455 0.0003
GSE53622 PIGX 54965 61950 0.4662 0.0000
GSE53624 PIGX 54965 61950 0.9396 0.0000
GSE63941 PIGX 54965 1563111_a_at 1.6786 0.0025
GSE77861 PIGX 54965 1563111_a_at 1.3747 0.0102
GSE97050 PIGX 54965 A_33_P3242388 0.0277 0.9553
SRP007169 PIGX 54965 RNAseq 1.0963 0.0041
SRP008496 PIGX 54965 RNAseq 1.2125 0.0003
SRP064894 PIGX 54965 RNAseq 0.9688 0.0000
SRP133303 PIGX 54965 RNAseq 1.0367 0.0006
SRP159526 PIGX 54965 RNAseq 1.8034 0.0000
SRP193095 PIGX 54965 RNAseq 1.2569 0.0000
SRP219564 PIGX 54965 RNAseq 0.5633 0.2183
TCGA PIGX 54965 RNAseq 0.3265 0.0000

Upregulated datasets: 9; Downregulated datasets: 0.  


 

Survival by PIGX expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PIGX:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PIGX 54965 22 0 8
GSE20123 PIGX 54965 22 0 8
GSE43470 PIGX 54965 21 0 22
GSE46452 PIGX 54965 19 1 39
GSE47630 PIGX 54965 27 2 11
GSE54993 PIGX 54965 1 22 47
GSE54994 PIGX 54965 41 0 12
GSE60625 PIGX 54965 0 6 5
GSE74703 PIGX 54965 19 0 17
GSE74704 PIGX 54965 14 0 6
TCGA PIGX 54965 76 1 19

Total number of gains: 262; Total number of losses: 32; Total Number of normals: 194.  


 

Somatic mutations of PIGX:

 

Generating mutation plots.

 

Highly correlated genes for PIGX:

 

Showing top 20/1119 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PIGXATG100.884664303
PIGXCOQ70.775846303
PIGXLRP5L0.772716303
PIGXMRPL470.762132808
PIGXFH0.756892404
PIGXINPP5B0.751075303
PIGXIMMP1L0.750765303
PIGXSLC4A20.750629303
PIGXALKBH60.750112404
PIGXABCB60.747223303
PIGXLRIF10.745968303
PIGXFAM32A0.745679303
PIGXSRSF70.744949404
PIGXEHD10.743355303
PIGXGDE10.743273303
PIGXZBED10.742933303
PIGXSLC4A50.73726303
PIGXATP13A30.734657707
PIGXGOLIM40.733048504
PIGXKLF130.732117403

For details and further investigation, click here