| Full name: solute carrier family 6 member 18 | Alias Symbol: FLJ31236|Xtrp2 | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 348932 | HGNC ID: HGNC:26441 | Ensembl Gene: ENSG00000164363 | OMIM ID: 610300 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC6A18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A18 | 348932 | 238215_at | -0.0055 | 0.9884 | |
| GSE26886 | SLC6A18 | 348932 | 238215_at | -0.0755 | 0.5904 | |
| GSE45670 | SLC6A18 | 348932 | 238215_at | -0.1182 | 0.2329 | |
| GSE53622 | SLC6A18 | 348932 | 142177 | 0.0776 | 0.2104 | |
| GSE53624 | SLC6A18 | 348932 | 142177 | -0.0282 | 0.7494 | |
| GSE63941 | SLC6A18 | 348932 | 238215_at | 0.1789 | 0.2037 | |
| GSE77861 | SLC6A18 | 348932 | 238215_at | -0.2751 | 0.0678 | |
| GSE97050 | SLC6A18 | 348932 | A_24_P212234 | 0.0804 | 0.7005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC6A18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A18 | 348932 | 13 | 1 | 16 | |
| GSE20123 | SLC6A18 | 348932 | 13 | 1 | 16 | |
| GSE43470 | SLC6A18 | 348932 | 17 | 1 | 25 | |
| GSE46452 | SLC6A18 | 348932 | 6 | 22 | 31 | |
| GSE47630 | SLC6A18 | 348932 | 7 | 11 | 22 | |
| GSE54993 | SLC6A18 | 348932 | 5 | 5 | 60 | |
| GSE54994 | SLC6A18 | 348932 | 29 | 1 | 23 | |
| GSE60625 | SLC6A18 | 348932 | 0 | 0 | 11 | |
| GSE74703 | SLC6A18 | 348932 | 14 | 0 | 22 | |
| GSE74704 | SLC6A18 | 348932 | 11 | 0 | 9 | |
| TCGA | SLC6A18 | 348932 | 61 | 3 | 32 |
Total number of gains: 176; Total number of losses: 45; Total Number of normals: 267.
Somatic mutations of SLC6A18:
Generating mutation plots.
Highly correlated genes for SLC6A18:
Showing top 20/381 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A18 | PHOSPHO1 | 0.813523 | 3 | 0 | 3 |
| SLC6A18 | C2CD4D | 0.781281 | 3 | 0 | 3 |
| SLC6A18 | ZNF329 | 0.779277 | 3 | 0 | 3 |
| SLC6A18 | LRFN2 | 0.77834 | 3 | 0 | 3 |
| SLC6A18 | TULP1 | 0.76912 | 3 | 0 | 3 |
| SLC6A18 | ICAM3 | 0.766476 | 3 | 0 | 3 |
| SLC6A18 | PHLDB3 | 0.765182 | 3 | 0 | 3 |
| SLC6A18 | EDA | 0.764775 | 3 | 0 | 3 |
| SLC6A18 | GH1 | 0.763896 | 3 | 0 | 3 |
| SLC6A18 | GPR78 | 0.760487 | 3 | 0 | 3 |
| SLC6A18 | FNDC9 | 0.758186 | 3 | 0 | 3 |
| SLC6A18 | MGAT5B | 0.751908 | 3 | 0 | 3 |
| SLC6A18 | RAD52 | 0.748488 | 3 | 0 | 3 |
| SLC6A18 | SH2D1B | 0.747335 | 3 | 0 | 3 |
| SLC6A18 | SLC22A25 | 0.746743 | 3 | 0 | 3 |
| SLC6A18 | SHISA7 | 0.745339 | 3 | 0 | 3 |
| SLC6A18 | ZGLP1 | 0.739238 | 4 | 0 | 3 |
| SLC6A18 | OR1J4 | 0.738949 | 3 | 0 | 3 |
| SLC6A18 | SLC48A1 | 0.738714 | 3 | 0 | 3 |
| SLC6A18 | PROCA1 | 0.736741 | 3 | 0 | 3 |
For details and further investigation, click here
