| Full name: protein interacting with cyclin A1 | Alias Symbol: MGC39650 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 147011 | HGNC ID: HGNC:28600 | Ensembl Gene: ENSG00000167525 | OMIM ID: 617376 |
| Drug and gene relationship at DGIdb | |||
Expression of PROCA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PROCA1 | 147011 | 236286_at | -0.1385 | 0.6849 | |
| GSE26886 | PROCA1 | 147011 | 236286_at | 0.0602 | 0.6329 | |
| GSE45670 | PROCA1 | 147011 | 236286_at | -0.0745 | 0.4751 | |
| GSE53622 | PROCA1 | 147011 | 42768 | 0.1898 | 0.0243 | |
| GSE53624 | PROCA1 | 147011 | 42768 | -0.0703 | 0.4094 | |
| GSE63941 | PROCA1 | 147011 | 236286_at | 0.8058 | 0.0016 | |
| GSE77861 | PROCA1 | 147011 | 232647_at | -0.1569 | 0.1869 | |
| GSE97050 | PROCA1 | 147011 | A_23_P427148 | -0.2517 | 0.3007 | |
| SRP064894 | PROCA1 | 147011 | RNAseq | 1.0080 | 0.0022 | |
| SRP133303 | PROCA1 | 147011 | RNAseq | -0.3050 | 0.1629 | |
| SRP159526 | PROCA1 | 147011 | RNAseq | 0.4447 | 0.2541 | |
| SRP219564 | PROCA1 | 147011 | RNAseq | 0.2185 | 0.6571 | |
| TCGA | PROCA1 | 147011 | RNAseq | -0.0589 | 0.7885 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PROCA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PROCA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PROCA1 | 147011 | 9 | 1 | 20 | |
| GSE20123 | PROCA1 | 147011 | 9 | 1 | 20 | |
| GSE43470 | PROCA1 | 147011 | 0 | 1 | 42 | |
| GSE46452 | PROCA1 | 147011 | 33 | 1 | 25 | |
| GSE47630 | PROCA1 | 147011 | 7 | 1 | 32 | |
| GSE54993 | PROCA1 | 147011 | 2 | 3 | 65 | |
| GSE54994 | PROCA1 | 147011 | 7 | 6 | 40 | |
| GSE60625 | PROCA1 | 147011 | 4 | 0 | 7 | |
| GSE74703 | PROCA1 | 147011 | 0 | 1 | 35 | |
| GSE74704 | PROCA1 | 147011 | 7 | 1 | 12 | |
| TCGA | PROCA1 | 147011 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of PROCA1:
Generating mutation plots.
Highly correlated genes for PROCA1:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PROCA1 | YY2 | 0.873348 | 3 | 0 | 3 |
| PROCA1 | MYO1A | 0.867581 | 3 | 0 | 3 |
| PROCA1 | PRSS38 | 0.837859 | 3 | 0 | 3 |
| PROCA1 | UROC1 | 0.833678 | 3 | 0 | 3 |
| PROCA1 | OR10AD1 | 0.816201 | 3 | 0 | 3 |
| PROCA1 | OR2B11 | 0.815156 | 3 | 0 | 3 |
| PROCA1 | C9orf153 | 0.807986 | 3 | 0 | 3 |
| PROCA1 | GPR182 | 0.802696 | 4 | 0 | 4 |
| PROCA1 | PLA2G2C | 0.802486 | 3 | 0 | 3 |
| PROCA1 | OTOG | 0.794277 | 3 | 0 | 3 |
| PROCA1 | KRTAP10-12 | 0.793242 | 3 | 0 | 3 |
| PROCA1 | GRIK4 | 0.790074 | 3 | 0 | 3 |
| PROCA1 | MUC2 | 0.787296 | 3 | 0 | 3 |
| PROCA1 | FFAR1 | 0.78419 | 4 | 0 | 4 |
| PROCA1 | OR2T1 | 0.783715 | 3 | 0 | 3 |
| PROCA1 | USP51 | 0.782448 | 3 | 0 | 3 |
| PROCA1 | DUOXA2 | 0.779875 | 3 | 0 | 3 |
| PROCA1 | LBX2 | 0.778608 | 3 | 0 | 3 |
| PROCA1 | OR2T27 | 0.778606 | 3 | 0 | 3 |
| PROCA1 | BBC3 | 0.777216 | 3 | 0 | 3 |
For details and further investigation, click here
