| Full name: solute carrier family 48 member 1 | Alias Symbol: FLJ20489|hHRG-1|HRG1 | ||
| Type: protein-coding gene | Cytoband: 12q13.11 | ||
| Entrez ID: 55652 | HGNC ID: HGNC:26035 | Ensembl Gene: ENSG00000211584 | OMIM ID: 612187 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC48A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC48A1 | 55652 | 48106_at | -0.3479 | 0.3622 | |
| GSE20347 | SLC48A1 | 55652 | 48106_at | -0.4682 | 0.0001 | |
| GSE23400 | SLC48A1 | 55652 | 48106_at | -0.3319 | 0.0000 | |
| GSE26886 | SLC48A1 | 55652 | 48106_at | -0.2885 | 0.0771 | |
| GSE29001 | SLC48A1 | 55652 | 48106_at | -0.5683 | 0.0074 | |
| GSE38129 | SLC48A1 | 55652 | 48106_at | -0.5006 | 0.0000 | |
| GSE45670 | SLC48A1 | 55652 | 48106_at | -0.0775 | 0.6700 | |
| GSE53622 | SLC48A1 | 55652 | 101555 | -0.4546 | 0.0000 | |
| GSE53624 | SLC48A1 | 55652 | 101555 | -0.6070 | 0.0000 | |
| GSE63941 | SLC48A1 | 55652 | 48106_at | 0.2861 | 0.6376 | |
| GSE77861 | SLC48A1 | 55652 | 48106_at | -0.2538 | 0.3251 | |
| GSE97050 | SLC48A1 | 55652 | A_33_P3353552 | -0.3276 | 0.3182 | |
| SRP007169 | SLC48A1 | 55652 | RNAseq | -0.4858 | 0.2687 | |
| SRP008496 | SLC48A1 | 55652 | RNAseq | -0.6432 | 0.0435 | |
| SRP064894 | SLC48A1 | 55652 | RNAseq | -0.5804 | 0.0086 | |
| SRP133303 | SLC48A1 | 55652 | RNAseq | -0.6861 | 0.0001 | |
| SRP159526 | SLC48A1 | 55652 | RNAseq | -0.2039 | 0.5252 | |
| SRP193095 | SLC48A1 | 55652 | RNAseq | 0.0398 | 0.8626 | |
| SRP219564 | SLC48A1 | 55652 | RNAseq | -0.4362 | 0.1231 | |
| TCGA | SLC48A1 | 55652 | RNAseq | -0.0470 | 0.5694 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC48A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC48A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC48A1 | 55652 | 6 | 1 | 23 | |
| GSE20123 | SLC48A1 | 55652 | 6 | 1 | 23 | |
| GSE43470 | SLC48A1 | 55652 | 3 | 1 | 39 | |
| GSE46452 | SLC48A1 | 55652 | 8 | 1 | 50 | |
| GSE47630 | SLC48A1 | 55652 | 11 | 2 | 27 | |
| GSE54993 | SLC48A1 | 55652 | 0 | 5 | 65 | |
| GSE54994 | SLC48A1 | 55652 | 6 | 1 | 46 | |
| GSE60625 | SLC48A1 | 55652 | 0 | 0 | 11 | |
| GSE74703 | SLC48A1 | 55652 | 3 | 1 | 32 | |
| GSE74704 | SLC48A1 | 55652 | 4 | 1 | 15 | |
| TCGA | SLC48A1 | 55652 | 16 | 12 | 68 |
Total number of gains: 63; Total number of losses: 26; Total Number of normals: 399.
Somatic mutations of SLC48A1:
Generating mutation plots.
Highly correlated genes for SLC48A1:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC48A1 | CPLX2 | 0.765345 | 3 | 0 | 3 |
| SLC48A1 | SLC6A18 | 0.738714 | 3 | 0 | 3 |
| SLC48A1 | KLHL10 | 0.713265 | 4 | 0 | 4 |
| SLC48A1 | MMP17 | 0.703342 | 3 | 0 | 3 |
| SLC48A1 | FXYD2 | 0.702717 | 3 | 0 | 3 |
| SLC48A1 | OR2C1 | 0.699824 | 3 | 0 | 3 |
| SLC48A1 | OR10G8 | 0.690647 | 3 | 0 | 3 |
| SLC48A1 | TMEM217 | 0.686687 | 5 | 0 | 4 |
| SLC48A1 | MYO1A | 0.678967 | 4 | 0 | 3 |
| SLC48A1 | MFSD2B | 0.673484 | 3 | 0 | 3 |
| SLC48A1 | EPN2 | 0.670634 | 3 | 0 | 3 |
| SLC48A1 | PHLDB3 | 0.66153 | 6 | 0 | 5 |
| SLC48A1 | BTBD19 | 0.660589 | 3 | 0 | 3 |
| SLC48A1 | MYH7B | 0.658528 | 3 | 0 | 3 |
| SLC48A1 | NUDT13 | 0.656473 | 3 | 0 | 3 |
| SLC48A1 | PTCRA | 0.65575 | 5 | 0 | 3 |
| SLC48A1 | CELF3 | 0.654366 | 4 | 0 | 3 |
| SLC48A1 | DNAH6 | 0.651838 | 3 | 0 | 3 |
| SLC48A1 | SPRY3 | 0.647449 | 3 | 0 | 3 |
| SLC48A1 | SNX21 | 0.647211 | 4 | 0 | 3 |
For details and further investigation, click here
