| Full name: intercellular adhesion molecule 3 | Alias Symbol: CDW50|ICAM-R|CD50 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 3385 | HGNC ID: HGNC:5346 | Ensembl Gene: ENSG00000076662 | OMIM ID: 146631 |
| Drug and gene relationship at DGIdb | |||
Expression of ICAM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ICAM3 | 3385 | 204949_at | 0.2810 | 0.7646 | |
| GSE20347 | ICAM3 | 3385 | 204949_at | -0.8461 | 0.0001 | |
| GSE23400 | ICAM3 | 3385 | 204949_at | -0.3438 | 0.0000 | |
| GSE26886 | ICAM3 | 3385 | 204949_at | -0.9503 | 0.0020 | |
| GSE29001 | ICAM3 | 3385 | 204949_at | -0.8286 | 0.0490 | |
| GSE38129 | ICAM3 | 3385 | 204949_at | -0.8575 | 0.0003 | |
| GSE45670 | ICAM3 | 3385 | 204949_at | -0.4487 | 0.0293 | |
| GSE63941 | ICAM3 | 3385 | 204949_at | -1.1584 | 0.1578 | |
| GSE77861 | ICAM3 | 3385 | 204949_at | -0.4219 | 0.0428 | |
| GSE97050 | ICAM3 | 3385 | A_23_P164691 | 0.3491 | 0.3129 | |
| SRP007169 | ICAM3 | 3385 | RNAseq | -1.4226 | 0.0007 | |
| SRP008496 | ICAM3 | 3385 | RNAseq | -1.6368 | 0.0000 | |
| SRP064894 | ICAM3 | 3385 | RNAseq | 0.0593 | 0.8518 | |
| SRP133303 | ICAM3 | 3385 | RNAseq | -0.3885 | 0.0514 | |
| SRP159526 | ICAM3 | 3385 | RNAseq | -0.5567 | 0.3589 | |
| SRP193095 | ICAM3 | 3385 | RNAseq | -0.2843 | 0.2098 | |
| SRP219564 | ICAM3 | 3385 | RNAseq | 0.1457 | 0.6269 | |
| TCGA | ICAM3 | 3385 | RNAseq | -0.2784 | 0.0107 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ICAM3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ICAM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ICAM3 | 3385 | 4 | 3 | 23 | |
| GSE20123 | ICAM3 | 3385 | 3 | 1 | 26 | |
| GSE43470 | ICAM3 | 3385 | 3 | 6 | 34 | |
| GSE46452 | ICAM3 | 3385 | 47 | 1 | 11 | |
| GSE47630 | ICAM3 | 3385 | 4 | 7 | 29 | |
| GSE54993 | ICAM3 | 3385 | 16 | 3 | 51 | |
| GSE54994 | ICAM3 | 3385 | 7 | 13 | 33 | |
| GSE60625 | ICAM3 | 3385 | 9 | 0 | 2 | |
| GSE74703 | ICAM3 | 3385 | 3 | 4 | 29 | |
| GSE74704 | ICAM3 | 3385 | 0 | 1 | 19 | |
| TCGA | ICAM3 | 3385 | 13 | 15 | 68 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of ICAM3:
Generating mutation plots.
Highly correlated genes for ICAM3:
Showing top 20/240 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ICAM3 | GABRD | 0.845018 | 3 | 0 | 3 |
| ICAM3 | SLC6A18 | 0.766476 | 3 | 0 | 3 |
| ICAM3 | TBC1D10C | 0.73412 | 6 | 0 | 6 |
| ICAM3 | ALOX5 | 0.731516 | 7 | 0 | 6 |
| ICAM3 | ADAMTS13 | 0.71525 | 3 | 0 | 3 |
| ICAM3 | MEGF11 | 0.713457 | 3 | 0 | 3 |
| ICAM3 | CD52 | 0.683282 | 9 | 0 | 8 |
| ICAM3 | PRKCB | 0.676818 | 6 | 0 | 5 |
| ICAM3 | ERCC5 | 0.668843 | 4 | 0 | 3 |
| ICAM3 | BCL6B | 0.667113 | 3 | 0 | 3 |
| ICAM3 | CHTF8 | 0.66687 | 3 | 0 | 3 |
| ICAM3 | PTPRCAP | 0.66662 | 8 | 0 | 8 |
| ICAM3 | ARHGAP30 | 0.661372 | 5 | 0 | 4 |
| ICAM3 | FERMT3 | 0.651267 | 4 | 0 | 3 |
| ICAM3 | GMIP | 0.651213 | 6 | 0 | 6 |
| ICAM3 | FANK1 | 0.651015 | 3 | 0 | 3 |
| ICAM3 | CD48 | 0.647392 | 10 | 0 | 9 |
| ICAM3 | SHC3 | 0.631616 | 3 | 0 | 3 |
| ICAM3 | NRG4 | 0.63068 | 3 | 0 | 3 |
| ICAM3 | KLB | 0.628791 | 3 | 0 | 3 |
For details and further investigation, click here
