| Full name: asialoglycoprotein receptor 2 | Alias Symbol: CLEC4H2 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 433 | HGNC ID: HGNC:743 | Ensembl Gene: ENSG00000161944 | OMIM ID: 108361 |
| Drug and gene relationship at DGIdb | |||
Expression of ASGR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASGR2 | 433 | 206130_s_at | -0.0248 | 0.9513 | |
| GSE20347 | ASGR2 | 433 | 206130_s_at | -0.0158 | 0.8850 | |
| GSE23400 | ASGR2 | 433 | 206130_s_at | -0.1177 | 0.0226 | |
| GSE26886 | ASGR2 | 433 | 206130_s_at | 0.2655 | 0.0445 | |
| GSE29001 | ASGR2 | 433 | 206130_s_at | -0.0624 | 0.6499 | |
| GSE38129 | ASGR2 | 433 | 206130_s_at | -0.0458 | 0.7749 | |
| GSE45670 | ASGR2 | 433 | 206130_s_at | 0.0084 | 0.9434 | |
| GSE53622 | ASGR2 | 433 | 120283 | -0.3867 | 0.0001 | |
| GSE53624 | ASGR2 | 433 | 120283 | -0.4622 | 0.0000 | |
| GSE63941 | ASGR2 | 433 | 206130_s_at | 0.2307 | 0.1976 | |
| GSE77861 | ASGR2 | 433 | 206130_s_at | -0.1626 | 0.1266 | |
| GSE97050 | ASGR2 | 433 | A_23_P130113 | 0.1311 | 0.4940 | |
| TCGA | ASGR2 | 433 | RNAseq | 0.6405 | 0.2413 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASGR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASGR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASGR2 | 433 | 4 | 2 | 24 | |
| GSE20123 | ASGR2 | 433 | 4 | 3 | 23 | |
| GSE43470 | ASGR2 | 433 | 1 | 4 | 38 | |
| GSE46452 | ASGR2 | 433 | 34 | 1 | 24 | |
| GSE47630 | ASGR2 | 433 | 7 | 1 | 32 | |
| GSE54993 | ASGR2 | 433 | 4 | 3 | 63 | |
| GSE54994 | ASGR2 | 433 | 5 | 8 | 40 | |
| GSE60625 | ASGR2 | 433 | 4 | 0 | 7 | |
| GSE74703 | ASGR2 | 433 | 1 | 2 | 33 | |
| GSE74704 | ASGR2 | 433 | 2 | 1 | 17 | |
| TCGA | ASGR2 | 433 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of ASGR2:
Generating mutation plots.
Highly correlated genes for ASGR2:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASGR2 | SLC6A19 | 0.695688 | 4 | 0 | 3 |
| ASGR2 | DEFB123 | 0.67775 | 3 | 0 | 3 |
| ASGR2 | RTBDN | 0.674463 | 3 | 0 | 3 |
| ASGR2 | ATP8B3 | 0.674196 | 5 | 0 | 5 |
| ASGR2 | ERC2-IT1 | 0.674022 | 6 | 0 | 6 |
| ASGR2 | KHDRBS2 | 0.669352 | 4 | 0 | 4 |
| ASGR2 | MTUS2-AS1 | 0.661459 | 3 | 0 | 3 |
| ASGR2 | FTCD | 0.660022 | 6 | 0 | 5 |
| ASGR2 | A1CF | 0.654593 | 4 | 0 | 4 |
| ASGR2 | ABCA4 | 0.654233 | 4 | 0 | 3 |
| ASGR2 | ARFIP2 | 0.652924 | 3 | 0 | 3 |
| ASGR2 | HMBS | 0.650703 | 3 | 0 | 3 |
| ASGR2 | PCYT2 | 0.647193 | 3 | 0 | 3 |
| ASGR2 | FSCN3 | 0.641634 | 8 | 0 | 8 |
| ASGR2 | GML | 0.638382 | 5 | 0 | 5 |
| ASGR2 | F11 | 0.637158 | 4 | 0 | 3 |
| ASGR2 | MUC2 | 0.635833 | 7 | 0 | 6 |
| ASGR2 | TLE6 | 0.635704 | 5 | 0 | 4 |
| ASGR2 | OLIG3 | 0.632142 | 3 | 0 | 3 |
| ASGR2 | TERT | 0.630638 | 6 | 0 | 5 |
For details and further investigation, click here
