| Full name: leucine rich repeat containing 71 | Alias Symbol: FLJ32884 | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 149499 | HGNC ID: HGNC:26556 | Ensembl Gene: ENSG00000160838 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LRRC71:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC71 | 149499 | 237251_at | 0.0153 | 0.9740 | |
| GSE26886 | LRRC71 | 149499 | 237251_at | 0.3071 | 0.0160 | |
| GSE45670 | LRRC71 | 149499 | 237251_at | -0.0188 | 0.8991 | |
| GSE53622 | LRRC71 | 149499 | 75570 | 0.5819 | 0.0000 | |
| GSE53624 | LRRC71 | 149499 | 75570 | 0.4714 | 0.0004 | |
| GSE63941 | LRRC71 | 149499 | 237251_at | 0.5257 | 0.0073 | |
| GSE77861 | LRRC71 | 149499 | 237251_at | -0.0138 | 0.9337 | |
| GSE97050 | LRRC71 | 149499 | A_23_P374919 | -0.0698 | 0.8221 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC71 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LRRC71:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC71 | 149499 | 11 | 0 | 19 | |
| GSE20123 | LRRC71 | 149499 | 11 | 0 | 19 | |
| GSE43470 | LRRC71 | 149499 | 7 | 2 | 34 | |
| GSE46452 | LRRC71 | 149499 | 2 | 1 | 56 | |
| GSE47630 | LRRC71 | 149499 | 14 | 0 | 26 | |
| GSE54993 | LRRC71 | 149499 | 0 | 5 | 65 | |
| GSE54994 | LRRC71 | 149499 | 16 | 0 | 37 | |
| GSE60625 | LRRC71 | 149499 | 0 | 0 | 11 | |
| GSE74703 | LRRC71 | 149499 | 7 | 2 | 27 | |
| GSE74704 | LRRC71 | 149499 | 6 | 0 | 14 | |
| TCGA | LRRC71 | 149499 | 38 | 3 | 55 |
Total number of gains: 112; Total number of losses: 13; Total Number of normals: 363.
Somatic mutations of LRRC71:
Generating mutation plots.
Highly correlated genes for LRRC71:
Showing top 20/421 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC71 | TMEM235 | 0.788031 | 4 | 0 | 4 |
| LRRC71 | STRC | 0.78609 | 3 | 0 | 3 |
| LRRC71 | ST8SIA3 | 0.773693 | 3 | 0 | 3 |
| LRRC71 | C9orf153 | 0.754497 | 3 | 0 | 3 |
| LRRC71 | GRIK4 | 0.749673 | 3 | 0 | 3 |
| LRRC71 | SLC5A5 | 0.747386 | 3 | 0 | 3 |
| LRRC71 | PLA2G2C | 0.745161 | 3 | 0 | 3 |
| LRRC71 | CDHR5 | 0.743103 | 3 | 0 | 3 |
| LRRC71 | SLC6A19 | 0.738195 | 3 | 0 | 3 |
| LRRC71 | SPANXN4 | 0.736619 | 3 | 0 | 3 |
| LRRC71 | ALPP | 0.731377 | 3 | 0 | 3 |
| LRRC71 | IFNL2 | 0.729844 | 3 | 0 | 3 |
| LRRC71 | ELOVL3 | 0.727656 | 3 | 0 | 3 |
| LRRC71 | PTPRN | 0.725066 | 3 | 0 | 3 |
| LRRC71 | FMR1NB | 0.722977 | 3 | 0 | 3 |
| LRRC71 | KRT74 | 0.720661 | 3 | 0 | 3 |
| LRRC71 | CSH1 | 0.714013 | 3 | 0 | 3 |
| LRRC71 | KLF17 | 0.713869 | 3 | 0 | 3 |
| LRRC71 | FOXB1 | 0.709966 | 3 | 0 | 3 |
| LRRC71 | NRSN1 | 0.708598 | 3 | 0 | 3 |
For details and further investigation, click here
