| Full name: sperm associated antigen 11B | Alias Symbol: HE2|EP2|EP2C|EP2D|EDDM2B | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 10407 | HGNC ID: HGNC:14534 | Ensembl Gene: ENSG00000164871 | OMIM ID: 606560 |
| Drug and gene relationship at DGIdb | |||
Expression of SPAG11B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SPAG11B | 10407 | 4264 | -0.0011 | 0.9936 | |
| GSE53624 | SPAG11B | 10407 | 4264 | -0.3308 | 0.0005 | |
| GSE97050 | SPAG11B | 10407 | A_23_P425116 | -0.0238 | 0.9410 | |
| TCGA | SPAG11B | 10407 | RNAseq | 1.1557 | 0.5297 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPAG11B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPAG11B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG11B | 10407 | 4 | 10 | 16 | |
| GSE20123 | SPAG11B | 10407 | 4 | 10 | 16 | |
| GSE43470 | SPAG11B | 10407 | 4 | 10 | 29 | |
| GSE46452 | SPAG11B | 10407 | 12 | 14 | 33 | |
| GSE47630 | SPAG11B | 10407 | 8 | 10 | 22 | |
| GSE54993 | SPAG11B | 10407 | 3 | 14 | 53 | |
| GSE54994 | SPAG11B | 10407 | 10 | 19 | 24 | |
| GSE60625 | SPAG11B | 10407 | 3 | 0 | 8 | |
| GSE74703 | SPAG11B | 10407 | 4 | 8 | 24 | |
| GSE74704 | SPAG11B | 10407 | 3 | 7 | 10 | |
| TCGA | SPAG11B | 10407 | 13 | 40 | 43 |
Total number of gains: 68; Total number of losses: 142; Total Number of normals: 278.
Somatic mutations of SPAG11B:
Generating mutation plots.
Highly correlated genes for SPAG11B:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG11B | KRTAP9-6 | 0.68258 | 3 | 0 | 3 |
| SPAG11B | USP17L2 | 0.646212 | 3 | 0 | 3 |
| SPAG11B | OR4D10 | 0.63495 | 3 | 0 | 3 |
| SPAG11B | SPEG | 0.634804 | 3 | 0 | 3 |
| SPAG11B | CCIN | 0.63251 | 3 | 0 | 3 |
| SPAG11B | OR1L6 | 0.629606 | 3 | 0 | 3 |
| SPAG11B | OR11A1 | 0.625518 | 3 | 0 | 3 |
| SPAG11B | GRIA4 | 0.611535 | 3 | 0 | 3 |
| SPAG11B | KIR3DL2 | 0.607551 | 3 | 0 | 3 |
| SPAG11B | CDH24 | 0.601386 | 3 | 0 | 3 |
| SPAG11B | SLC4A8 | 0.595347 | 3 | 0 | 3 |
| SPAG11B | SLAMF9 | 0.585562 | 3 | 0 | 3 |
| SPAG11B | SZT2 | 0.57277 | 3 | 0 | 3 |
| SPAG11B | CCDC154 | 0.571194 | 3 | 0 | 3 |
| SPAG11B | ZNF248 | 0.569454 | 3 | 0 | 3 |
| SPAG11B | KRTAP4-3 | 0.567839 | 3 | 0 | 3 |
| SPAG11B | LMLN | 0.561744 | 3 | 0 | 3 |
| SPAG11B | GH2 | 0.560619 | 3 | 0 | 3 |
| SPAG11B | SLC36A4 | 0.559422 | 3 | 0 | 3 |
| SPAG11B | KRTAP10-9 | 0.557492 | 3 | 0 | 3 |
For details and further investigation, click here
