| Full name: ubiquitin specific peptidase 17 like family member 2 | Alias Symbol: DUB3 | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 377630 | HGNC ID: HGNC:34434 | Ensembl Gene: ENSG00000223443 | OMIM ID: 610186 |
| Drug and gene relationship at DGIdb | |||
Expression of USP17L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | USP17L2 | 377630 | 141922 | 0.7904 | 0.0006 | |
| GSE53624 | USP17L2 | 377630 | 141922 | 0.5204 | 0.0001 | |
| GSE97050 | USP17L2 | 377630 | A_33_P3292739 | -0.2369 | 0.4696 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP17L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP17L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP17L2 | 377630 | 4 | 10 | 16 | |
| GSE20123 | USP17L2 | 377630 | 4 | 10 | 16 | |
| GSE43470 | USP17L2 | 377630 | 4 | 9 | 30 | |
| GSE46452 | USP17L2 | 377630 | 12 | 14 | 33 | |
| GSE47630 | USP17L2 | 377630 | 10 | 7 | 23 | |
| GSE54993 | USP17L2 | 377630 | 3 | 14 | 53 | |
| GSE54994 | USP17L2 | 377630 | 9 | 16 | 28 | |
| GSE60625 | USP17L2 | 377630 | 3 | 0 | 8 | |
| GSE74703 | USP17L2 | 377630 | 4 | 7 | 25 | |
| GSE74704 | USP17L2 | 377630 | 3 | 7 | 10 | |
| TCGA | USP17L2 | 377630 | 14 | 39 | 43 |
Total number of gains: 70; Total number of losses: 133; Total Number of normals: 285.
Somatic mutations of USP17L2:
Generating mutation plots.
Highly correlated genes for USP17L2:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP17L2 | ZNF445 | 0.804616 | 3 | 0 | 3 |
| USP17L2 | GRIA4 | 0.778277 | 3 | 0 | 3 |
| USP17L2 | CDH24 | 0.768468 | 3 | 0 | 3 |
| USP17L2 | OR2T33 | 0.760477 | 3 | 0 | 3 |
| USP17L2 | CCDC154 | 0.755428 | 3 | 0 | 3 |
| USP17L2 | SPEG | 0.753587 | 3 | 0 | 3 |
| USP17L2 | CCIN | 0.746928 | 3 | 0 | 3 |
| USP17L2 | ZNF248 | 0.744388 | 3 | 0 | 3 |
| USP17L2 | ALG11 | 0.742515 | 3 | 0 | 3 |
| USP17L2 | OR1L6 | 0.732865 | 3 | 0 | 3 |
| USP17L2 | SZT2 | 0.732706 | 3 | 0 | 3 |
| USP17L2 | SLC38A6 | 0.727672 | 3 | 0 | 3 |
| USP17L2 | OR2AT4 | 0.725675 | 3 | 0 | 3 |
| USP17L2 | BARHL1 | 0.71799 | 3 | 0 | 3 |
| USP17L2 | RBM17 | 0.717885 | 3 | 0 | 3 |
| USP17L2 | FAM111B | 0.709287 | 3 | 0 | 3 |
| USP17L2 | LEPROTL1 | 0.706469 | 3 | 0 | 3 |
| USP17L2 | SLC4A8 | 0.705114 | 3 | 0 | 3 |
| USP17L2 | CTPS2 | 0.702723 | 3 | 0 | 3 |
| USP17L2 | CELA3A | 0.702225 | 3 | 0 | 3 |
For details and further investigation, click here
