| Full name: keratin associated protein 4-3 | Alias Symbol: KAP4.3 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 85290 | HGNC ID: HGNC:18908 | Ensembl Gene: ENSG00000196156 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP4-3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTAP4-3 | 85290 | 234678_at | -0.0352 | 0.8857 | |
| GSE26886 | KRTAP4-3 | 85290 | 234678_at | -0.0248 | 0.8451 | |
| GSE45670 | KRTAP4-3 | 85290 | 234678_at | 0.0584 | 0.3259 | |
| GSE53622 | KRTAP4-3 | 85290 | 152450 | -0.0179 | 0.8549 | |
| GSE53624 | KRTAP4-3 | 85290 | 152450 | -0.2968 | 0.0006 | |
| GSE63941 | KRTAP4-3 | 85290 | 234678_at | -0.2538 | 0.0695 | |
| GSE77861 | KRTAP4-3 | 85290 | 234678_at | -0.0721 | 0.3703 | |
| GSE97050 | KRTAP4-3 | 85290 | A_33_P3312743 | -0.1982 | 0.3196 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP4-3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP4-3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP4-3 | 85290 | 7 | 1 | 22 | |
| GSE20123 | KRTAP4-3 | 85290 | 7 | 1 | 22 | |
| GSE43470 | KRTAP4-3 | 85290 | 1 | 2 | 40 | |
| GSE46452 | KRTAP4-3 | 85290 | 34 | 0 | 25 | |
| GSE47630 | KRTAP4-3 | 85290 | 8 | 1 | 31 | |
| GSE54993 | KRTAP4-3 | 85290 | 3 | 4 | 63 | |
| GSE54994 | KRTAP4-3 | 85290 | 8 | 5 | 40 | |
| GSE60625 | KRTAP4-3 | 85290 | 4 | 0 | 7 | |
| GSE74703 | KRTAP4-3 | 85290 | 1 | 1 | 34 | |
| GSE74704 | KRTAP4-3 | 85290 | 4 | 1 | 15 |
Total number of gains: 77; Total number of losses: 16; Total Number of normals: 299.
Somatic mutations of KRTAP4-3:
Generating mutation plots.
Highly correlated genes for KRTAP4-3:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP4-3 | CISH | 0.787409 | 3 | 0 | 3 |
| KRTAP4-3 | KRTAP9-6 | 0.717725 | 3 | 0 | 3 |
| KRTAP4-3 | ACHE | 0.677337 | 3 | 0 | 3 |
| KRTAP4-3 | KRTAP5-8 | 0.670229 | 4 | 0 | 3 |
| KRTAP4-3 | HLA-DQB2 | 0.668669 | 3 | 0 | 3 |
| KRTAP4-3 | TRIM3 | 0.656266 | 3 | 0 | 3 |
| KRTAP4-3 | PDCD4 | 0.633552 | 4 | 0 | 3 |
| KRTAP4-3 | DNAH11 | 0.618107 | 4 | 0 | 3 |
| KRTAP4-3 | CCDC40 | 0.611425 | 4 | 0 | 3 |
| KRTAP4-3 | TMEM38A | 0.605901 | 4 | 0 | 3 |
| KRTAP4-3 | GH2 | 0.604465 | 4 | 0 | 3 |
| KRTAP4-3 | F10 | 0.604214 | 4 | 0 | 4 |
| KRTAP4-3 | OR4D10 | 0.603989 | 3 | 0 | 3 |
| KRTAP4-3 | STBD1 | 0.60264 | 3 | 0 | 3 |
| KRTAP4-3 | KIAA0895L | 0.599137 | 4 | 0 | 3 |
| KRTAP4-3 | KCNQ3 | 0.594942 | 5 | 0 | 3 |
| KRTAP4-3 | ARHGAP26-AS1 | 0.59483 | 3 | 0 | 3 |
| KRTAP4-3 | OR3A1 | 0.590279 | 4 | 0 | 4 |
| KRTAP4-3 | C9orf47 | 0.588979 | 3 | 0 | 3 |
| KRTAP4-3 | C9orf50 | 0.588373 | 4 | 0 | 3 |
For details and further investigation, click here
