| Full name: leishmanolysin like peptidase | Alias Symbol: Gp63|Msp|LMNL1 | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 89782 | HGNC ID: HGNC:15991 | Ensembl Gene: ENSG00000185621 | OMIM ID: 609380 |
| Drug and gene relationship at DGIdb | |||
Expression of LMLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMLN | 89782 | 244881_at | 0.6276 | 0.4470 | |
| GSE26886 | LMLN | 89782 | 244881_at | 0.6557 | 0.0393 | |
| GSE45670 | LMLN | 89782 | 244881_at | 0.9538 | 0.0000 | |
| GSE53622 | LMLN | 89782 | 99023 | -0.2672 | 0.0048 | |
| GSE53624 | LMLN | 89782 | 99023 | -0.2221 | 0.0293 | |
| GSE63941 | LMLN | 89782 | 244881_at | 0.3590 | 0.5143 | |
| GSE77861 | LMLN | 89782 | 244881_at | 0.5814 | 0.1106 | |
| GSE97050 | LMLN | 89782 | A_23_P170959 | 0.5809 | 0.2041 | |
| SRP007169 | LMLN | 89782 | RNAseq | 1.4794 | 0.0176 | |
| SRP008496 | LMLN | 89782 | RNAseq | 1.4996 | 0.0003 | |
| SRP064894 | LMLN | 89782 | RNAseq | 0.5319 | 0.0530 | |
| SRP133303 | LMLN | 89782 | RNAseq | 0.9593 | 0.0000 | |
| SRP159526 | LMLN | 89782 | RNAseq | 1.1796 | 0.0064 | |
| SRP193095 | LMLN | 89782 | RNAseq | 0.3920 | 0.0022 | |
| SRP219564 | LMLN | 89782 | RNAseq | 0.5247 | 0.2404 | |
| TCGA | LMLN | 89782 | RNAseq | 0.2625 | 0.0016 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LMLN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMLN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMLN | 89782 | 23 | 0 | 7 | |
| GSE20123 | LMLN | 89782 | 23 | 0 | 7 | |
| GSE43470 | LMLN | 89782 | 22 | 0 | 21 | |
| GSE46452 | LMLN | 89782 | 20 | 1 | 38 | |
| GSE47630 | LMLN | 89782 | 27 | 2 | 11 | |
| GSE54993 | LMLN | 89782 | 1 | 22 | 47 | |
| GSE54994 | LMLN | 89782 | 41 | 0 | 12 | |
| GSE60625 | LMLN | 89782 | 0 | 6 | 5 | |
| GSE74703 | LMLN | 89782 | 20 | 0 | 16 | |
| GSE74704 | LMLN | 89782 | 14 | 0 | 6 | |
| TCGA | LMLN | 89782 | 76 | 1 | 19 |
Total number of gains: 267; Total number of losses: 32; Total Number of normals: 189.
Somatic mutations of LMLN:
Generating mutation plots.
Highly correlated genes for LMLN:
Showing top 20/314 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMLN | NAA25 | 0.831075 | 3 | 0 | 3 |
| LMLN | FNBP1L | 0.823306 | 3 | 0 | 3 |
| LMLN | NUDT19 | 0.819131 | 3 | 0 | 3 |
| LMLN | CNOT2 | 0.812012 | 3 | 0 | 3 |
| LMLN | RBM26 | 0.804218 | 3 | 0 | 3 |
| LMLN | TMEM181 | 0.800149 | 3 | 0 | 3 |
| LMLN | POU2F1 | 0.782019 | 3 | 0 | 3 |
| LMLN | ZNF121 | 0.776905 | 4 | 0 | 4 |
| LMLN | RNF114 | 0.765252 | 3 | 0 | 3 |
| LMLN | ZBTB44 | 0.765169 | 3 | 0 | 3 |
| LMLN | SPEN | 0.764818 | 3 | 0 | 3 |
| LMLN | CELF1 | 0.764788 | 4 | 0 | 4 |
| LMLN | DCAF16 | 0.756751 | 3 | 0 | 3 |
| LMLN | PRKCI | 0.755505 | 4 | 0 | 4 |
| LMLN | ZNF766 | 0.755083 | 3 | 0 | 3 |
| LMLN | ZNF668 | 0.74643 | 3 | 0 | 3 |
| LMLN | ZNF250 | 0.742138 | 3 | 0 | 3 |
| LMLN | RPL39L | 0.741546 | 3 | 0 | 3 |
| LMLN | LSG1 | 0.740799 | 5 | 0 | 5 |
| LMLN | TOR1A | 0.735681 | 3 | 0 | 3 |
For details and further investigation, click here
