| Full name: spermatid maturation 1 | Alias Symbol: FLJ40081 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 374768 | HGNC ID: HGNC:32429 | Ensembl Gene: ENSG00000181323 | OMIM ID: 615116 |
| Drug and gene relationship at DGIdb | |||
Expression of SPEM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPEM1 | 374768 | 240878_at | -0.0322 | 0.9369 | |
| GSE26886 | SPEM1 | 374768 | 240878_at | 0.1562 | 0.3293 | |
| GSE45670 | SPEM1 | 374768 | 240878_at | 0.0524 | 0.6939 | |
| GSE53622 | SPEM1 | 374768 | 41731 | 0.5354 | 0.0000 | |
| GSE53624 | SPEM1 | 374768 | 41731 | 0.0476 | 0.5768 | |
| GSE63941 | SPEM1 | 374768 | 240878_at | 0.6758 | 0.0011 | |
| GSE77861 | SPEM1 | 374768 | 240878_at | -0.1285 | 0.3415 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPEM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPEM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPEM1 | 374768 | 4 | 2 | 24 | |
| GSE20123 | SPEM1 | 374768 | 4 | 3 | 23 | |
| GSE43470 | SPEM1 | 374768 | 1 | 4 | 38 | |
| GSE46452 | SPEM1 | 374768 | 34 | 1 | 24 | |
| GSE47630 | SPEM1 | 374768 | 7 | 1 | 32 | |
| GSE54993 | SPEM1 | 374768 | 4 | 3 | 63 | |
| GSE54994 | SPEM1 | 374768 | 5 | 8 | 40 | |
| GSE60625 | SPEM1 | 374768 | 4 | 0 | 7 | |
| GSE74703 | SPEM1 | 374768 | 1 | 2 | 33 | |
| GSE74704 | SPEM1 | 374768 | 2 | 1 | 17 | |
| TCGA | SPEM1 | 374768 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of SPEM1:
Generating mutation plots.
Highly correlated genes for SPEM1:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPEM1 | ODF3B | 0.675489 | 3 | 0 | 3 |
| SPEM1 | TTC9B | 0.668413 | 3 | 0 | 3 |
| SPEM1 | MEPE | 0.656111 | 3 | 0 | 3 |
| SPEM1 | MIR4755 | 0.655259 | 3 | 0 | 3 |
| SPEM1 | LINC01118 | 0.652507 | 3 | 0 | 3 |
| SPEM1 | C20orf203 | 0.638985 | 3 | 0 | 3 |
| SPEM1 | NKD1 | 0.636644 | 3 | 0 | 3 |
| SPEM1 | TMEM102 | 0.635608 | 3 | 0 | 3 |
| SPEM1 | C10orf90 | 0.634163 | 3 | 0 | 3 |
| SPEM1 | CELF3 | 0.62751 | 4 | 0 | 4 |
| SPEM1 | RGL3 | 0.625943 | 3 | 0 | 3 |
| SPEM1 | PHGR1 | 0.62583 | 3 | 0 | 3 |
| SPEM1 | NPPA | 0.625713 | 3 | 0 | 3 |
| SPEM1 | ZBTB7B | 0.62514 | 3 | 0 | 3 |
| SPEM1 | SOX10 | 0.618503 | 3 | 0 | 3 |
| SPEM1 | GLT1D1 | 0.617761 | 3 | 0 | 3 |
| SPEM1 | ROS1 | 0.616762 | 3 | 0 | 3 |
| SPEM1 | LRRC43 | 0.615262 | 3 | 0 | 3 |
| SPEM1 | PRAM1 | 0.611652 | 3 | 0 | 3 |
| SPEM1 | HOXD9 | 0.608828 | 3 | 0 | 3 |
For details and further investigation, click here
