| Full name: zinc finger and BTB domain containing 7B | Alias Symbol: ZBTB15|c-Krox|hcKrox|ZNF857B | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 51043 | HGNC ID: HGNC:18668 | Ensembl Gene: ENSG00000160685 | OMIM ID: 607646 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZBTB7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB7B | 51043 | 235145_at | 0.1574 | 0.7941 | |
| GSE20347 | ZBTB7B | 51043 | 205853_at | -0.1889 | 0.0138 | |
| GSE23400 | ZBTB7B | 51043 | 205853_at | -0.2174 | 0.0000 | |
| GSE26886 | ZBTB7B | 51043 | 235145_at | -0.0504 | 0.8194 | |
| GSE29001 | ZBTB7B | 51043 | 205853_at | -0.3587 | 0.0140 | |
| GSE38129 | ZBTB7B | 51043 | 205853_at | -0.3111 | 0.0001 | |
| GSE45670 | ZBTB7B | 51043 | 235145_at | -0.0870 | 0.4961 | |
| GSE53622 | ZBTB7B | 51043 | 19755 | -1.0568 | 0.0000 | |
| GSE53624 | ZBTB7B | 51043 | 19755 | -0.9702 | 0.0000 | |
| GSE63941 | ZBTB7B | 51043 | 235145_at | 0.7146 | 0.0017 | |
| GSE77861 | ZBTB7B | 51043 | 235145_at | -0.1862 | 0.4931 | |
| GSE97050 | ZBTB7B | 51043 | A_23_P11729 | -0.0545 | 0.8232 | |
| SRP007169 | ZBTB7B | 51043 | RNAseq | -2.7496 | 0.0000 | |
| SRP008496 | ZBTB7B | 51043 | RNAseq | -2.3730 | 0.0000 | |
| SRP064894 | ZBTB7B | 51043 | RNAseq | -1.1021 | 0.0000 | |
| SRP133303 | ZBTB7B | 51043 | RNAseq | -0.9116 | 0.0000 | |
| SRP159526 | ZBTB7B | 51043 | RNAseq | -0.8239 | 0.1272 | |
| SRP193095 | ZBTB7B | 51043 | RNAseq | -0.9552 | 0.0000 | |
| SRP219564 | ZBTB7B | 51043 | RNAseq | -1.0972 | 0.0767 | |
| TCGA | ZBTB7B | 51043 | RNAseq | -0.0990 | 0.1009 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZBTB7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB7B | 51043 | 14 | 0 | 16 | |
| GSE20123 | ZBTB7B | 51043 | 13 | 0 | 17 | |
| GSE43470 | ZBTB7B | 51043 | 6 | 2 | 35 | |
| GSE46452 | ZBTB7B | 51043 | 2 | 1 | 56 | |
| GSE47630 | ZBTB7B | 51043 | 14 | 0 | 26 | |
| GSE54993 | ZBTB7B | 51043 | 0 | 4 | 66 | |
| GSE54994 | ZBTB7B | 51043 | 16 | 0 | 37 | |
| GSE60625 | ZBTB7B | 51043 | 0 | 0 | 11 | |
| GSE74703 | ZBTB7B | 51043 | 6 | 1 | 29 | |
| GSE74704 | ZBTB7B | 51043 | 6 | 0 | 14 | |
| TCGA | ZBTB7B | 51043 | 38 | 2 | 56 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of ZBTB7B:
Generating mutation plots.
Highly correlated genes for ZBTB7B:
Showing top 20/1121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB7B | NCCRP1 | 0.831942 | 3 | 0 | 3 |
| ZBTB7B | SDCBP2 | 0.775072 | 3 | 0 | 3 |
| ZBTB7B | RAET1E | 0.774918 | 4 | 0 | 4 |
| ZBTB7B | UPK3B | 0.770239 | 3 | 0 | 3 |
| ZBTB7B | ARHGAP40 | 0.767266 | 3 | 0 | 3 |
| ZBTB7B | DEGS2 | 0.741624 | 5 | 0 | 5 |
| ZBTB7B | OTOP3 | 0.734063 | 3 | 0 | 3 |
| ZBTB7B | RNF222 | 0.733178 | 3 | 0 | 3 |
| ZBTB7B | SPRR2E | 0.73301 | 3 | 0 | 3 |
| ZBTB7B | SPRR2F | 0.732918 | 3 | 0 | 3 |
| ZBTB7B | SPRR2D | 0.732365 | 3 | 0 | 3 |
| ZBTB7B | CEACAM3 | 0.732044 | 8 | 0 | 8 |
| ZBTB7B | KPRP | 0.729813 | 3 | 0 | 3 |
| ZBTB7B | RARG | 0.72357 | 11 | 0 | 11 |
| ZBTB7B | HMGB4 | 0.722239 | 3 | 0 | 3 |
| ZBTB7B | TMPRSS11A | 0.721948 | 3 | 0 | 3 |
| ZBTB7B | VSIG10L | 0.720635 | 5 | 0 | 4 |
| ZBTB7B | PLEKHN1 | 0.719736 | 7 | 0 | 7 |
| ZBTB7B | FAM163B | 0.717181 | 3 | 0 | 3 |
| ZBTB7B | GRHL1 | 0.710541 | 5 | 0 | 5 |
For details and further investigation, click here
