| Full name: serine/threonine kinase 38 | Alias Symbol: NDR|NDR1 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 11329 | HGNC ID: HGNC:17847 | Ensembl Gene: ENSG00000112079 | OMIM ID: 606964 |
| Drug and gene relationship at DGIdb | |||
Expression of STK38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK38 | 11329 | 202951_at | 0.0889 | 0.9304 | |
| GSE20347 | STK38 | 11329 | 202951_at | -0.3154 | 0.0270 | |
| GSE23400 | STK38 | 11329 | 202951_at | -0.0390 | 0.6525 | |
| GSE26886 | STK38 | 11329 | 202951_at | -0.9370 | 0.0000 | |
| GSE29001 | STK38 | 11329 | 202951_at | -0.1458 | 0.5173 | |
| GSE38129 | STK38 | 11329 | 202951_at | -0.0819 | 0.5335 | |
| GSE45670 | STK38 | 11329 | 202951_at | 0.1248 | 0.4118 | |
| GSE53622 | STK38 | 11329 | 37995 | -0.4979 | 0.0000 | |
| GSE53624 | STK38 | 11329 | 37995 | -0.3751 | 0.0000 | |
| GSE63941 | STK38 | 11329 | 202951_at | -0.5174 | 0.3517 | |
| GSE77861 | STK38 | 11329 | 202951_at | -0.2779 | 0.2407 | |
| GSE97050 | STK38 | 11329 | A_23_P390704 | 0.0680 | 0.7989 | |
| SRP007169 | STK38 | 11329 | RNAseq | -0.9036 | 0.0289 | |
| SRP008496 | STK38 | 11329 | RNAseq | -0.9487 | 0.0000 | |
| SRP064894 | STK38 | 11329 | RNAseq | -0.1336 | 0.4711 | |
| SRP133303 | STK38 | 11329 | RNAseq | -0.1368 | 0.3978 | |
| SRP159526 | STK38 | 11329 | RNAseq | -0.4406 | 0.0421 | |
| SRP193095 | STK38 | 11329 | RNAseq | -0.5409 | 0.0000 | |
| SRP219564 | STK38 | 11329 | RNAseq | -0.1371 | 0.7075 | |
| TCGA | STK38 | 11329 | RNAseq | 0.0135 | 0.7919 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STK38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK38 | 11329 | 6 | 0 | 24 | |
| GSE20123 | STK38 | 11329 | 6 | 0 | 24 | |
| GSE43470 | STK38 | 11329 | 5 | 1 | 37 | |
| GSE46452 | STK38 | 11329 | 2 | 9 | 48 | |
| GSE47630 | STK38 | 11329 | 8 | 4 | 28 | |
| GSE54993 | STK38 | 11329 | 3 | 1 | 66 | |
| GSE54994 | STK38 | 11329 | 10 | 5 | 38 | |
| GSE60625 | STK38 | 11329 | 1 | 0 | 10 | |
| GSE74703 | STK38 | 11329 | 5 | 0 | 31 | |
| GSE74704 | STK38 | 11329 | 3 | 0 | 17 | |
| TCGA | STK38 | 11329 | 15 | 15 | 66 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of STK38:
Generating mutation plots.
Highly correlated genes for STK38:
Showing top 20/979 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK38 | RNF146 | 0.836663 | 3 | 0 | 3 |
| STK38 | ARFGAP2 | 0.835473 | 3 | 0 | 3 |
| STK38 | UGP2 | 0.821298 | 3 | 0 | 3 |
| STK38 | ZNRD1 | 0.808204 | 3 | 0 | 3 |
| STK38 | SRRM1 | 0.806061 | 3 | 0 | 3 |
| STK38 | C6orf120 | 0.801397 | 3 | 0 | 3 |
| STK38 | ZNF41 | 0.798031 | 3 | 0 | 3 |
| STK38 | AK3 | 0.795354 | 4 | 0 | 4 |
| STK38 | OSBPL8 | 0.787436 | 3 | 0 | 3 |
| STK38 | ZNF416 | 0.786261 | 4 | 0 | 3 |
| STK38 | PPP1R2 | 0.775955 | 3 | 0 | 3 |
| STK38 | CCNDBP1 | 0.773559 | 4 | 0 | 4 |
| STK38 | VPS26B | 0.769058 | 3 | 0 | 3 |
| STK38 | EPM2AIP1 | 0.768971 | 3 | 0 | 3 |
| STK38 | ZNF879 | 0.767743 | 4 | 0 | 4 |
| STK38 | PAPSS1 | 0.762017 | 3 | 0 | 3 |
| STK38 | YTHDF2 | 0.760773 | 4 | 0 | 4 |
| STK38 | C5orf51 | 0.759201 | 3 | 0 | 3 |
| STK38 | ZNF100 | 0.759004 | 3 | 0 | 3 |
| STK38 | AKT1S1 | 0.755482 | 3 | 0 | 3 |
For details and further investigation, click here
