| Full name: VPS26, retromer complex component B | Alias Symbol: MGC10485|Pep8b | ||
| Type: protein-coding gene | Cytoband: 11q25 | ||
| Entrez ID: 112936 | HGNC ID: HGNC:28119 | Ensembl Gene: ENSG00000151502 | OMIM ID: 610027 |
| Drug and gene relationship at DGIdb | |||
Expression of VPS26B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS26B | 112936 | 225483_at | 0.0966 | 0.7842 | |
| GSE26886 | VPS26B | 112936 | 225483_at | -0.8020 | 0.0033 | |
| GSE45670 | VPS26B | 112936 | 225483_at | -0.1572 | 0.3101 | |
| GSE53622 | VPS26B | 112936 | 113831 | -0.1453 | 0.0284 | |
| GSE53624 | VPS26B | 112936 | 113831 | -0.2127 | 0.0009 | |
| GSE63941 | VPS26B | 112936 | 225483_at | -0.9771 | 0.0261 | |
| GSE77861 | VPS26B | 112936 | 225483_at | -0.1072 | 0.5348 | |
| GSE97050 | VPS26B | 112936 | A_24_P107336 | -0.3788 | 0.1734 | |
| SRP007169 | VPS26B | 112936 | RNAseq | 0.2505 | 0.5623 | |
| SRP008496 | VPS26B | 112936 | RNAseq | 0.3397 | 0.3196 | |
| SRP064894 | VPS26B | 112936 | RNAseq | -0.2206 | 0.1488 | |
| SRP133303 | VPS26B | 112936 | RNAseq | -0.4911 | 0.0000 | |
| SRP159526 | VPS26B | 112936 | RNAseq | -0.5226 | 0.0092 | |
| SRP193095 | VPS26B | 112936 | RNAseq | -0.5717 | 0.0000 | |
| SRP219564 | VPS26B | 112936 | RNAseq | -0.3808 | 0.2002 | |
| TCGA | VPS26B | 112936 | RNAseq | -0.1755 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPS26B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS26B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS26B | 112936 | 0 | 15 | 15 | |
| GSE20123 | VPS26B | 112936 | 0 | 15 | 15 | |
| GSE43470 | VPS26B | 112936 | 2 | 8 | 33 | |
| GSE46452 | VPS26B | 112936 | 3 | 26 | 30 | |
| GSE47630 | VPS26B | 112936 | 2 | 19 | 19 | |
| GSE54993 | VPS26B | 112936 | 10 | 0 | 60 | |
| GSE54994 | VPS26B | 112936 | 5 | 18 | 30 | |
| GSE60625 | VPS26B | 112936 | 0 | 3 | 8 | |
| GSE74703 | VPS26B | 112936 | 1 | 5 | 30 | |
| GSE74704 | VPS26B | 112936 | 0 | 11 | 9 | |
| TCGA | VPS26B | 112936 | 6 | 49 | 41 |
Total number of gains: 29; Total number of losses: 169; Total Number of normals: 290.
Somatic mutations of VPS26B:
Generating mutation plots.
Highly correlated genes for VPS26B:
Showing top 20/378 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS26B | ATP6V1H | 0.801102 | 3 | 0 | 3 |
| VPS26B | NDUFS3 | 0.792152 | 3 | 0 | 3 |
| VPS26B | LARP4 | 0.789001 | 3 | 0 | 3 |
| VPS26B | UBE3C | 0.774697 | 3 | 0 | 3 |
| VPS26B | WDR77 | 0.77317 | 4 | 0 | 4 |
| VPS26B | SRP9 | 0.773085 | 3 | 0 | 3 |
| VPS26B | RAB11FIP2 | 0.770916 | 3 | 0 | 3 |
| VPS26B | FICD | 0.770263 | 3 | 0 | 3 |
| VPS26B | STK38 | 0.769058 | 3 | 0 | 3 |
| VPS26B | RNASEL | 0.752709 | 3 | 0 | 3 |
| VPS26B | ANAPC5 | 0.746472 | 3 | 0 | 3 |
| VPS26B | C15orf41 | 0.745121 | 3 | 0 | 3 |
| VPS26B | PINK1 | 0.742832 | 3 | 0 | 3 |
| VPS26B | FAM53B | 0.736758 | 4 | 0 | 3 |
| VPS26B | ZMAT3 | 0.735912 | 3 | 0 | 3 |
| VPS26B | ABHD16A | 0.735331 | 4 | 0 | 4 |
| VPS26B | CLIP1 | 0.735111 | 3 | 0 | 3 |
| VPS26B | AHCYL2 | 0.734901 | 3 | 0 | 3 |
| VPS26B | SCAMP3 | 0.734821 | 3 | 0 | 3 |
| VPS26B | MLLT1 | 0.73454 | 3 | 0 | 3 |
For details and further investigation, click here
