| Full name: UDP-glucose pyrophosphorylase 2 | Alias Symbol: UGPP1 | ||
| Type: protein-coding gene | Cytoband: 2p15 | ||
| Entrez ID: 7360 | HGNC ID: HGNC:12527 | Ensembl Gene: ENSG00000169764 | OMIM ID: 191760 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UGP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UGP2 | 7360 | 205480_s_at | -0.6471 | 0.1106 | |
| GSE20347 | UGP2 | 7360 | 205480_s_at | -0.6942 | 0.0001 | |
| GSE23400 | UGP2 | 7360 | 205480_s_at | -0.4333 | 0.0000 | |
| GSE26886 | UGP2 | 7360 | 205480_s_at | -1.1811 | 0.0001 | |
| GSE29001 | UGP2 | 7360 | 205480_s_at | -0.7674 | 0.1007 | |
| GSE38129 | UGP2 | 7360 | 205480_s_at | -0.6641 | 0.0000 | |
| GSE45670 | UGP2 | 7360 | 205480_s_at | -0.5110 | 0.0004 | |
| GSE63941 | UGP2 | 7360 | 205480_s_at | -0.0395 | 0.9223 | |
| GSE77861 | UGP2 | 7360 | 205480_s_at | -0.6054 | 0.0233 | |
| GSE97050 | UGP2 | 7360 | A_23_P253046 | -0.5690 | 0.0885 | |
| SRP007169 | UGP2 | 7360 | RNAseq | -0.9789 | 0.0081 | |
| SRP008496 | UGP2 | 7360 | RNAseq | -1.0450 | 0.0000 | |
| SRP064894 | UGP2 | 7360 | RNAseq | -0.5219 | 0.0007 | |
| SRP133303 | UGP2 | 7360 | RNAseq | -0.2331 | 0.1516 | |
| SRP159526 | UGP2 | 7360 | RNAseq | -0.4332 | 0.1194 | |
| SRP193095 | UGP2 | 7360 | RNAseq | -0.8745 | 0.0000 | |
| SRP219564 | UGP2 | 7360 | RNAseq | -0.7791 | 0.0053 | |
| TCGA | UGP2 | 7360 | RNAseq | -0.1480 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UGP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of UGP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UGP2 | 7360 | 12 | 0 | 18 | |
| GSE20123 | UGP2 | 7360 | 12 | 0 | 18 | |
| GSE43470 | UGP2 | 7360 | 7 | 0 | 36 | |
| GSE46452 | UGP2 | 7360 | 2 | 3 | 54 | |
| GSE47630 | UGP2 | 7360 | 8 | 0 | 32 | |
| GSE54993 | UGP2 | 7360 | 0 | 6 | 64 | |
| GSE54994 | UGP2 | 7360 | 12 | 0 | 41 | |
| GSE60625 | UGP2 | 7360 | 0 | 3 | 8 | |
| GSE74703 | UGP2 | 7360 | 7 | 0 | 29 | |
| GSE74704 | UGP2 | 7360 | 10 | 0 | 10 | |
| TCGA | UGP2 | 7360 | 36 | 2 | 58 |
Total number of gains: 106; Total number of losses: 14; Total Number of normals: 368.
Somatic mutations of UGP2:
Generating mutation plots.
Highly correlated genes for UGP2:
Showing top 20/1480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UGP2 | STK38 | 0.821298 | 3 | 0 | 3 |
| UGP2 | ALG14 | 0.804597 | 3 | 0 | 3 |
| UGP2 | USP38 | 0.787985 | 3 | 0 | 3 |
| UGP2 | HERPUD1 | 0.771709 | 3 | 0 | 3 |
| UGP2 | BLOC1S2 | 0.771233 | 3 | 0 | 3 |
| UGP2 | CCNDBP1 | 0.770471 | 6 | 0 | 6 |
| UGP2 | PLEKHF2 | 0.769893 | 4 | 0 | 4 |
| UGP2 | STXBP5 | 0.7692 | 4 | 0 | 4 |
| UGP2 | PCBD2 | 0.769198 | 4 | 0 | 4 |
| UGP2 | ZNF564 | 0.767807 | 3 | 0 | 3 |
| UGP2 | SPRYD4 | 0.767223 | 3 | 0 | 3 |
| UGP2 | COMMD1 | 0.767084 | 4 | 0 | 4 |
| UGP2 | ABLIM2 | 0.763903 | 3 | 0 | 3 |
| UGP2 | MED8 | 0.761965 | 4 | 0 | 4 |
| UGP2 | BRK1 | 0.76174 | 5 | 0 | 4 |
| UGP2 | PTGR1 | 0.760982 | 5 | 0 | 5 |
| UGP2 | SLTM | 0.757713 | 4 | 0 | 3 |
| UGP2 | HOOK3 | 0.757121 | 4 | 0 | 4 |
| UGP2 | LMBRD1 | 0.756768 | 10 | 0 | 10 |
| UGP2 | GRPEL2 | 0.755396 | 3 | 0 | 3 |
For details and further investigation, click here
