| Full name: surfeit 6 | Alias Symbol: FLJ30322|RRP14 | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 6838 | HGNC ID: HGNC:11478 | Ensembl Gene: ENSG00000148296 | OMIM ID: 185642 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SURF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SURF6 | 6838 | 225038_s_at | 0.4957 | 0.1717 | |
| GSE26886 | SURF6 | 6838 | 225038_s_at | 0.6322 | 0.0004 | |
| GSE45670 | SURF6 | 6838 | 225038_s_at | 0.4036 | 0.0023 | |
| GSE53622 | SURF6 | 6838 | 24118 | 0.0451 | 0.6855 | |
| GSE53624 | SURF6 | 6838 | 24118 | 0.5238 | 0.0000 | |
| GSE63941 | SURF6 | 6838 | 225038_s_at | 0.6072 | 0.0405 | |
| GSE77861 | SURF6 | 6838 | 225038_s_at | 0.3474 | 0.0764 | |
| GSE97050 | SURF6 | 6838 | A_24_P21447 | -0.2996 | 0.3440 | |
| SRP007169 | SURF6 | 6838 | RNAseq | 0.7892 | 0.0854 | |
| SRP008496 | SURF6 | 6838 | RNAseq | 0.9557 | 0.0578 | |
| SRP064894 | SURF6 | 6838 | RNAseq | 0.6008 | 0.0100 | |
| SRP133303 | SURF6 | 6838 | RNAseq | -0.0315 | 0.7868 | |
| SRP159526 | SURF6 | 6838 | RNAseq | 0.4976 | 0.0867 | |
| SRP193095 | SURF6 | 6838 | RNAseq | 0.1720 | 0.0955 | |
| SRP219564 | SURF6 | 6838 | RNAseq | 0.1845 | 0.6531 | |
| TCGA | SURF6 | 6838 | RNAseq | 0.0842 | 0.1333 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SURF6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SURF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SURF6 | 6838 | 5 | 7 | 18 | |
| GSE20123 | SURF6 | 6838 | 5 | 7 | 18 | |
| GSE43470 | SURF6 | 6838 | 4 | 7 | 32 | |
| GSE46452 | SURF6 | 6838 | 6 | 13 | 40 | |
| GSE47630 | SURF6 | 6838 | 4 | 15 | 21 | |
| GSE54993 | SURF6 | 6838 | 3 | 3 | 64 | |
| GSE54994 | SURF6 | 6838 | 12 | 9 | 32 | |
| GSE60625 | SURF6 | 6838 | 0 | 0 | 11 | |
| GSE74703 | SURF6 | 6838 | 4 | 5 | 27 | |
| GSE74704 | SURF6 | 6838 | 3 | 5 | 12 | |
| TCGA | SURF6 | 6838 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of SURF6:
Generating mutation plots.
Highly correlated genes for SURF6:
Showing top 20/1203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SURF6 | ZNF584 | 0.847826 | 3 | 0 | 3 |
| SURF6 | ANKRD17 | 0.836226 | 3 | 0 | 3 |
| SURF6 | FIP1L1 | 0.833412 | 3 | 0 | 3 |
| SURF6 | PACSIN3 | 0.820911 | 3 | 0 | 3 |
| SURF6 | SFSWAP | 0.795856 | 3 | 0 | 3 |
| SURF6 | ZNF567 | 0.795778 | 3 | 0 | 3 |
| SURF6 | PPP1R37 | 0.794034 | 3 | 0 | 3 |
| SURF6 | SIPA1L2 | 0.784918 | 3 | 0 | 3 |
| SURF6 | NUP43 | 0.778339 | 4 | 0 | 4 |
| SURF6 | RLIM | 0.771306 | 3 | 0 | 3 |
| SURF6 | SLC25A28 | 0.76642 | 3 | 0 | 3 |
| SURF6 | EID2 | 0.76598 | 3 | 0 | 3 |
| SURF6 | FGF12 | 0.760796 | 3 | 0 | 3 |
| SURF6 | VGLL4 | 0.760769 | 3 | 0 | 3 |
| SURF6 | MAP2K7 | 0.757917 | 4 | 0 | 4 |
| SURF6 | ZBTB11 | 0.756345 | 3 | 0 | 3 |
| SURF6 | DDB1 | 0.751367 | 3 | 0 | 3 |
| SURF6 | RPL19 | 0.750135 | 3 | 0 | 3 |
| SURF6 | ULK1 | 0.749276 | 3 | 0 | 3 |
| SURF6 | PJA1 | 0.746554 | 3 | 0 | 3 |
For details and further investigation, click here
