| Full name: nucleoporin 43 | Alias Symbol: bA350J20.1|FLJ13287 | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 348995 | HGNC ID: HGNC:21182 | Ensembl Gene: ENSG00000120253 | OMIM ID: 608141 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUP43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP43 | 348995 | 219007_at | 0.9630 | 0.0136 | |
| GSE20347 | NUP43 | 348995 | 219007_at | 0.5071 | 0.0015 | |
| GSE23400 | NUP43 | 348995 | 219007_at | 0.6454 | 0.0000 | |
| GSE26886 | NUP43 | 348995 | 219007_at | 1.2176 | 0.0000 | |
| GSE29001 | NUP43 | 348995 | 219007_at | 0.8066 | 0.0016 | |
| GSE38129 | NUP43 | 348995 | 219007_at | 0.5391 | 0.0000 | |
| GSE45670 | NUP43 | 348995 | 219007_at | 0.3521 | 0.0259 | |
| GSE53622 | NUP43 | 348995 | 10626 | 0.3468 | 0.0000 | |
| GSE53624 | NUP43 | 348995 | 3471 | 0.5987 | 0.0000 | |
| GSE63941 | NUP43 | 348995 | 219007_at | 0.3816 | 0.3200 | |
| GSE77861 | NUP43 | 348995 | 219007_at | 0.2874 | 0.0522 | |
| GSE97050 | NUP43 | 348995 | A_33_P3273063 | 0.3519 | 0.3345 | |
| SRP007169 | NUP43 | 348995 | RNAseq | 0.9260 | 0.0226 | |
| SRP008496 | NUP43 | 348995 | RNAseq | 0.6825 | 0.0178 | |
| SRP064894 | NUP43 | 348995 | RNAseq | 0.2302 | 0.1661 | |
| SRP133303 | NUP43 | 348995 | RNAseq | 0.3063 | 0.0851 | |
| SRP159526 | NUP43 | 348995 | RNAseq | 0.2921 | 0.1158 | |
| SRP193095 | NUP43 | 348995 | RNAseq | 0.0300 | 0.7389 | |
| SRP219564 | NUP43 | 348995 | RNAseq | 0.2744 | 0.3901 | |
| TCGA | NUP43 | 348995 | RNAseq | 0.0199 | 0.6984 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NUP43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP43 | 348995 | 2 | 4 | 24 | |
| GSE20123 | NUP43 | 348995 | 1 | 3 | 26 | |
| GSE43470 | NUP43 | 348995 | 4 | 0 | 39 | |
| GSE46452 | NUP43 | 348995 | 3 | 10 | 46 | |
| GSE47630 | NUP43 | 348995 | 9 | 4 | 27 | |
| GSE54993 | NUP43 | 348995 | 3 | 2 | 65 | |
| GSE54994 | NUP43 | 348995 | 8 | 8 | 37 | |
| GSE60625 | NUP43 | 348995 | 0 | 1 | 10 | |
| GSE74703 | NUP43 | 348995 | 4 | 0 | 32 | |
| GSE74704 | NUP43 | 348995 | 0 | 1 | 19 | |
| TCGA | NUP43 | 348995 | 10 | 22 | 64 |
Total number of gains: 44; Total number of losses: 55; Total Number of normals: 389.
Somatic mutations of NUP43:
Generating mutation plots.
Highly correlated genes for NUP43:
Showing top 20/1769 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP43 | PDCD2L | 0.832046 | 3 | 0 | 3 |
| NUP43 | TRMT61A | 0.794221 | 3 | 0 | 3 |
| NUP43 | MAP3K11 | 0.780192 | 5 | 0 | 5 |
| NUP43 | SURF6 | 0.778339 | 4 | 0 | 4 |
| NUP43 | PHF5A | 0.775395 | 3 | 0 | 3 |
| NUP43 | MIER2 | 0.768645 | 3 | 0 | 3 |
| NUP43 | SLC25A29 | 0.764448 | 3 | 0 | 3 |
| NUP43 | KDM6B | 0.761506 | 3 | 0 | 3 |
| NUP43 | FHL3 | 0.755362 | 3 | 0 | 3 |
| NUP43 | MRPL50 | 0.747129 | 4 | 0 | 4 |
| NUP43 | KLHL8 | 0.746916 | 4 | 0 | 4 |
| NUP43 | C2orf69 | 0.744164 | 4 | 0 | 4 |
| NUP43 | MRPL55 | 0.739214 | 5 | 0 | 4 |
| NUP43 | SFR1 | 0.738735 | 5 | 0 | 5 |
| NUP43 | DHX37 | 0.734329 | 5 | 0 | 4 |
| NUP43 | ZC3H3 | 0.733823 | 4 | 0 | 4 |
| NUP43 | NAF1 | 0.732408 | 4 | 0 | 4 |
| NUP43 | TRPC4AP | 0.731239 | 3 | 0 | 3 |
| NUP43 | DYRK2 | 0.730468 | 3 | 0 | 3 |
| NUP43 | RHBDF2 | 0.727574 | 3 | 0 | 3 |
For details and further investigation, click here
